STRINGSTRING
dmrt1 dmrt1 dmrt2a dmrt2a slc11a2 slc11a2 dmrt3a dmrt3a sox8b sox8b dmrta2 dmrta2 foxl2a foxl2a sox9b sox9b sox10 sox10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dmrt1Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in sex determination and differentiation by controlling gonad development and germ cell proliferation. Acts both as a transcription repressor and activator (By similarity); Belongs to the DMRT family. (268 aa)
dmrt2aDoublesex and mab-3-related transcription factor 2a. (507 aa)
slc11a2Solute carrier family 11 member 2. (231 aa)
dmrt3aDoublesex- and mab-3-related transcription factor 3a; Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements. May regulate transcription (By similarity); Belongs to the DMRT family. (448 aa)
sox8bSRY-box transcription factor 8b. (356 aa)
dmrta2Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development; Belongs to the DMRT family. (440 aa)
foxl2aForkhead box L2-1. (306 aa)
sox9bHMG box transcription factor Sox9b. (407 aa)
sox10HMG-box transcription factor Sox10. (485 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]