STRINGSTRING
gapdh gapdh myh7 myh7 vclb vclb vcla vcla nrap nrap grna grna tbx16l tbx16l tnnt3b tnnt3b tnnt2a tnnt2a mybpc2a mybpc2a tln1 tln1 tln2a tln2a smyhc2-2 smyhc2-2 csrp3 csrp3 mybpc3 mybpc3 tln2b tln2b lmna lmna tbx6 tbx6 isl1 isl1 mybpc1 mybpc1 tnni2a.4 tnni2a.4 nkx2.5 nkx2.5 gapdhs gapdhs acta1b acta1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
myh7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
vclbVinculin b. (987 aa)
vclaVinculin a. (1131 aa)
nrapNebulin-related-anchoring protein. (1861 aa)
grnaGranulin a. (1049 aa)
tbx16lT-box transcription factor TBX6L; Probable transcriptional regulator involved in developmental processes. (488 aa)
tnnt3bTroponin T type 3b (skeletal, fast). (284 aa)
tnnt2aTroponin T type 2a (cardiac). (282 aa)
mybpc2aMyosin-binding protein Ca. (1131 aa)
tln1Talin 1. (2544 aa)
tln2aTalin 2a. (2543 aa)
smyhc2-2Slow myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (184 aa)
csrp3Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
mybpc3Myosin-binding protein C3. (1287 aa)
tln2bTalin 2b. (1537 aa)
lmnaLamin A; Belongs to the intermediate filament family. (675 aa)
tbx6T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm. (874 aa)
isl1Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). (349 aa)
mybpc1Myosin-binding protein C1. (1167 aa)
tnni2a.4Troponin I type 2a (skeletal, fast), tandem duplicate 4. (176 aa)
nkx2.5NK2 homeobox 5. (314 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.