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pparg | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (116 aa) | ||||
pparab | Peroxisome proliferator-activated receptor alpha b. (459 aa) | ||||
pparaa | Peroxisome proliferator-activated receptor alpha a. (470 aa) | ||||
tnfb | Tumor necrosis factor b (TNF superfamily, member 2). (242 aa) | ||||
il10 | Interleukin-10. (180 aa) |