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sufu | Suppressor of fused homolog. (485 aa) | ||||
gli1 | GLI family zinc finger 1. (1404 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
ENSDARP00000125042 | Patched 1. (120 aa) | ||||
poc5 | POC5 centriolar protein homolog (Chlamydomonas). (567 aa) | ||||
krt18a.1 | Keratin, type I cytoskeletal 18; When phosphorylated, plays a role in filament reorganization. (431 aa) | ||||
vip | Vasoactive intestinal peptide. (153 aa) | ||||
dlg5a | Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1926 aa) | ||||
zgc:158846 | Zgc:158846; Belongs to the intermediate filament family. (486 aa) | ||||
ces2a | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (555 aa) | ||||
kif6 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (761 aa) | ||||
ptk7a | Protein tyrosine kinase 7a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa) | ||||
krt8 | Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. (520 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
ttc38 | Tetratricopeptide repeat protein 38; Belongs to the TTC38 family. (466 aa) | ||||
shhb | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. (416 aa) | ||||
dmd | Dystrophin. (594 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
kif7 | Kinesin-like protein kif7; Acts downstream of smo as an intracellular repressor of hedgehog signaling pathway, mainly through the suppression of gli1 activity. This negative regulatory effect is enhanced in conjunction with the suppressor of fused (sufu) protein. Positively regulates gli2a activity by promoting its dissociation from sufu. Involved in the regulation of microtubular dynamics. (1363 aa) | ||||
krt4 | Keratin 4; Belongs to the intermediate filament family. (497 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) |