STRINGSTRING
sod2 sod2 jun jun il10 il10 tlr4al tlr4al tlr4ba tlr4ba nos2a nos2a got1 got1 nos1 nos1 il1b il1b pparg pparg tnfb tnfb got2b got2b tlr4bb tlr4bb mpx mpx nos2b nos2b got2a got2a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa)
il10Interleukin-10. (180 aa)
tlr4alToll-like receptor 4a, like. (816 aa)
tlr4baToll-like receptor 4b, duplicate a. (787 aa)
nos2aNitric oxide synthase; Produces nitric oxide (NO). (1079 aa)
got1Aspartate aminotransferase. (410 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
il1bInterleukin-1. (284 aa)
ppargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (116 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
got2bAspartate aminotransferase. (428 aa)
tlr4bbToll-like receptor 4b, duplicate b. (819 aa)
mpxMyeloid-specific peroxidase. (893 aa)
nos2bNitric oxide synthase; Produces nitric oxide (NO). (1077 aa)
got2aAspartate aminotransferase. (428 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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