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mtpn | Myotrophin; Regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity); Belongs to the myotrophin family. (118 aa) | ||||
sirt2 | NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] (379 aa) | ||||
chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. (758 aa) | ||||
hsp90ab1 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (725 aa) | ||||
nfkbiab | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (312 aa) | ||||
slc35b2 | Solute carrier family 35, member B2. (435 aa) | ||||
INSM2 | INSM transcriptional repressor 2. (449 aa) | ||||
pold1 | DNA polymerase. (1105 aa) | ||||
rps5 | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa) | ||||
rel | V-rel avian reticuloendotheliosis viral oncogene homolog. (596 aa) | ||||
il10 | Interleukin-10. (180 aa) | ||||
fam177a1 | Family with sequence similarity 177 member A1. (206 aa) | ||||
pola1 | DNA polymerase. (1468 aa) | ||||
nfkbiaa | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa) | ||||
eef1a1b | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa) | ||||
rab6a | RAB6A, member RAS oncogene family. (208 aa) | ||||
eed | Polycomb protein eed; Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). (443 aa) | ||||
rela | V-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa) | ||||
fxyd6 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (99 aa) | ||||
cxcl8a | Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa) | ||||
il1b | Interleukin-1. (284 aa) | ||||
ccr2-2 | Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
ccr2 | Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (354 aa) | ||||
gjd1a | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (299 aa) |