node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gpx1a | gsr | ENSDARP00000020656 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.997 |
gpx1a | tomt | ENSDARP00000020656 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.571 |
gpx1b | gpx4b | ENSDARP00000011398 | ENSDARP00000154635 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.858 |
gpx1b | gpx7 | ENSDARP00000011398 | ENSDARP00000123903 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.657 |
gpx1b | gpx8 | ENSDARP00000011398 | ENSDARP00000011955 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. | 0.598 |
gpx1b | gsr | ENSDARP00000011398 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.997 |
gpx1b | tomt | ENSDARP00000011398 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.545 |
gpx3 | gsr | ENSDARP00000063624 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.992 |
gpx3 | tomt | ENSDARP00000063624 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.546 |
gpx4a | gpx4b | ENSDARP00000089830 | ENSDARP00000154635 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.902 |
gpx4a | gsr | ENSDARP00000089830 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.996 |
gpx4a | tomt | ENSDARP00000089830 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.544 |
gpx4b | gpx1b | ENSDARP00000154635 | ENSDARP00000011398 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.858 |
gpx4b | gpx4a | ENSDARP00000154635 | ENSDARP00000089830 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.902 |
gpx4b | gsr | ENSDARP00000154635 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.995 |
gpx4b | tomt | ENSDARP00000154635 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.545 |
gpx7 | gpx1b | ENSDARP00000123903 | ENSDARP00000011398 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.657 |
gpx7 | gsr | ENSDARP00000123903 | ENSDARP00000047049 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.996 |
gpx7 | tomt | ENSDARP00000123903 | ENSDARP00000145949 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. | 0.545 |
gpx8 | gpx1b | ENSDARP00000011955 | ENSDARP00000011398 | Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.598 |