Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC798445 | apaf1 | ENSDARP00000107531 | ENSDARP00000008347 | Uncharacterized protein; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | 0.864 |
| LOC798445 | bcl2a | ENSDARP00000107531 | ENSDARP00000120749 | Uncharacterized protein; Belongs to the peptidase C14A family. | B-cell leukemia/lymphoma 2. | 0.802 |
| LOC798445 | casp21 | ENSDARP00000107531 | ENSDARP00000072390 | Uncharacterized protein; Belongs to the peptidase C14A family. | Caspase 21, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.905 |
| LOC798445 | caspa | ENSDARP00000107531 | ENSDARP00000034228 | Uncharacterized protein; Belongs to the peptidase C14A family. | Caspase a subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form. Its subsequent activation causes the cleavage of pro-il1b into the midformed il1b, which then evetually leads to il1b maturation and secretion in the extracellular milieu. Required for the [...] | 0.644 |
| LOC798445 | cycsb | ENSDARP00000107531 | ENSDARP00000034555 | Uncharacterized protein; Belongs to the peptidase C14A family. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.842 |
| LOC798445 | tnfb | ENSDARP00000107531 | ENSDARP00000010728 | Uncharacterized protein; Belongs to the peptidase C14A family. | Tumor necrosis factor b (TNF superfamily, member 2). | 0.481 |
| apaf1 | LOC798445 | ENSDARP00000008347 | ENSDARP00000107531 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.864 |
| apaf1 | bcl2a | ENSDARP00000008347 | ENSDARP00000120749 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | B-cell leukemia/lymphoma 2. | 0.975 |
| apaf1 | casp21 | ENSDARP00000008347 | ENSDARP00000072390 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 21, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.850 |
| apaf1 | casp3a | ENSDARP00000008347 | ENSDARP00000006831 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.963 |
| apaf1 | casp3b | ENSDARP00000008347 | ENSDARP00000071815 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.938 |
| apaf1 | caspa | ENSDARP00000008347 | ENSDARP00000034228 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase a subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form. Its subsequent activation causes the cleavage of pro-il1b into the midformed il1b, which then evetually leads to il1b maturation and secretion in the extracellular milieu. Required for the [...] | 0.799 |
| apaf1 | cycsb | ENSDARP00000008347 | ENSDARP00000034555 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.999 |
| apaf1 | gapdh | ENSDARP00000008347 | ENSDARP00000063799 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.528 |
| apaf1 | gapdhs | ENSDARP00000008347 | ENSDARP00000058383 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. | 0.508 |
| apaf1 | gpx1a | ENSDARP00000008347 | ENSDARP00000020656 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.517 |
| apaf1 | gpx1b | ENSDARP00000008347 | ENSDARP00000011398 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.480 |
| apaf1 | gpx3 | ENSDARP00000008347 | ENSDARP00000063624 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.440 |
| apaf1 | gpx4a | ENSDARP00000008347 | ENSDARP00000089830 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.477 |
| apaf1 | gpx4b | ENSDARP00000008347 | ENSDARP00000154635 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.483 |
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