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sycp3 sycp3 sox9a sox9a amh amh sult1st6 sult1st6 star star cyp11a1 cyp11a1 cldn11a cldn11a vangl1 vangl1 cyp17a1 cyp17a1 lama5 lama5 hsd3b7 hsd3b7 cyp11c1 cyp11c1 foxl2a foxl2a sox9b sox9b cyp17a2 cyp17a2 tnn tnn dmc1 dmc1 esr1 esr1 nanos3 nanos3 foxl2b foxl2b hsd20b2 hsd20b2 si:dkey-7e14.3 si:dkey-7e14.3 dmrt1 dmrt1 esr2a esr2a cyp19a1a cyp19a1a cyp11a2 cyp11a2 esr2b esr2b gldn gldn irx3a irx3a anxa1b anxa1b nanos1 nanos1 nanos2 nanos2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sycp3Synaptonemal complex protein 3 like. (240 aa)
sox9aHMG box transcription factor Sox9a. (462 aa)
amhAnti-Mullerian hormone. (549 aa)
sult1st6Sulfotransferase; Belongs to the sulfotransferase 1 family. (308 aa)
starSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). (285 aa)
cyp11a1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (509 aa)
cldn11aClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
vangl1Vang-like protein. (527 aa)
cyp17a1Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
lama5Laminin, alpha 5. (3664 aa)
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (368 aa)
cyp11c1Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (628 aa)
foxl2aForkhead box L2-1. (306 aa)
sox9bHMG box transcription factor Sox9b. (407 aa)
cyp17a2Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (495 aa)
tnnTenascin N. (932 aa)
dmc1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (569 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (159 aa)
foxl2bForkhead box L2-like protein. (285 aa)
hsd20b220beta-hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (329 aa)
si:dkey-7e14.3Si:dkey-7e14.3. (220 aa)
dmrt1Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in sex determination and differentiation by controlling gonad development and germ cell proliferation. Acts both as a transcription repressor and activator (By similarity); Belongs to the DMRT family. (268 aa)
esr2aEstrogen receptor beta2. (553 aa)
cyp19a1aAromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (517 aa)
cyp11a2Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
esr2bEstrogen receptor 2b. (592 aa)
gldnGliomedin. (564 aa)
irx3aIroquois 3 homeobox protein. (454 aa)
anxa1bAnnexin. (342 aa)
nanos1Nanos homolog 1; Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES- driven, polyadenylated RNAs or nonpolyadenylated RNAs (By similarity). Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival. (228 aa)
nanos2Nanos homolog 2; Belongs to the nanos family. (146 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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