STRINGSTRING
ENSDARP00000060652 ENSDARP00000060652 ush2a ush2a TMC1 TMC1 whrna whrna whrnb whrnb rp2 rp2 pdzd7a pdzd7a adgrv1 adgrv1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSDARP00000060652Si:ch211-57i17.5. (199 aa)
ush2aUsher syndrome 2A (autosomal recessive, mild). (5236 aa)
TMC1Transmembrane channel-like protein 1; Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery ; Belongs to the TMC family. (990 aa)
whrnaWhirlin a. (939 aa)
whrnbWhirlin b. (946 aa)
rp2Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane (By similarity). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization (By similarity). In the retina, required for maintenance of rod and cone photoreceptor cells. May have a role in normal retinal localization of the transducins GNB1 and GNAT1, and the rhodopsin kinase GRK1. (376 aa)
pdzd7aPDZ domain-containing 7a. (954 aa)
adgrv1Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. (6198 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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