STRINGSTRING
hspd1 hspd1 opn1mw4 opn1mw4 opn1mw1 opn1mw1 nr4a1 nr4a1 opn1mw3 opn1mw3 cd74a cd74a ndel1a ndel1a cct7 cct7 sirt2 sirt2 rpl3 rpl3 cct3 cct3 rpl5a rpl5a psma8 psma8 zap70 zap70 per1b per1b atp5l atp5l pou4f1 pou4f1 gria1a gria1a hsp70.3 hsp70.3 gad2 gad2 psmc2 psmc2 rho rho psmb1 psmb1 opn1mw2 opn1mw2 slc18a3a slc18a3a psmb3 psmb3 rpe65a rpe65a sdha sdha snx5 snx5 fabp7a fabp7a snap25a snap25a opn1sw2 opn1sw2 foxn4 foxn4 hes6 hes6 sucla2 sucla2 fabp11a fabp11a stmn1a stmn1a psmb6 psmb6 cct4 cct4 chata chata psmd3 psmd3 hmgcl hmgcl rbpms2b rbpms2b neurod1 neurod1 atp5fa1 atp5fa1 tuba8l4 tuba8l4 gatad2ab gatad2ab gsto1 gsto1 eno2 eno2 rprmb rprmb rtn4r rtn4r foxo3a foxo3a aqp1a.1 aqp1a.1 ptgdsb.1 ptgdsb.1 grin1b grin1b socs3a socs3a add3a add3a psmb2 psmb2 cacng2a cacng2a pfkfb3 pfkfb3 cx52.6 cx52.6 dctn2 dctn2 ciarta ciarta ephb2b ephb2b gria1b gria1b atp2a2b atp2a2b gria3a gria3a notch1b notch1b cdk7 cdk7 marcksl1b marcksl1b mdka mdka ccnb2 ccnb2 ndufv1 ndufv1 cd74b cd74b slc3a2b slc3a2b aurkb aurkb tubb5 tubb5 ndufa6 ndufa6 her15.1 her15.1 marcksl1a marcksl1a tefa tefa bbs5 bbs5 acta1b acta1b rgs16 rgs16 calb2a calb2a rpl4 rpl4 sdhb sdhb cyp51 cyp51 sesn1 sesn1 sod1 sod1 opn1lw1 opn1lw1 rdh10a rdh10a cct5 cct5 opn1sw1 opn1sw1 rlbp1b rlbp1b rbpms2a rbpms2a hyal6 hyal6 suclg1 suclg1 gria2b gria2b ppifb ppifb hsf2 hsf2 slc6a9 slc6a9 tuba1c tuba1c nr4a3 nr4a3 pfkfb4b pfkfb4b sik2b sik2b prodha prodha apc2 apc2 tmco1 tmco1 per1a per1a rpl6 rpl6 atoh7 atoh7 camsap1a camsap1a gria2a gria2a nsfa nsfa rhol rhol atp1a3a atp1a3a ptgdsb.2 ptgdsb.2 psmc5 psmc5 adh5 adh5 myca myca tjp1b tjp1b mertka mertka chgb chgb mtor mtor lamp2 lamp2 xbp1 xbp1 nrxn3b nrxn3b pgam1b pgam1b pfn1 pfn1 junba junba prdx5 prdx5 bada bada dct dct rac3b rac3b cx52.9 cx52.9 psmb7 psmb7 nr1d2b nr1d2b cry1a cry1a calb1 calb1 atp1b1b atp1b1b cacna1c cacna1c nxph2a nxph2a grin2aa grin2aa sqstm1 sqstm1 nxnl1 nxnl1 saga saga shank2b shank2b SDHB SDHB camsap1b camsap1b rpgrip1 rpgrip1 eno3 eno3 arl13a arl13a apoc1 apoc1 dnajb1b dnajb1b neurod4 neurod4 pde6b pde6b aco2 aco2 tulp1b tulp1b per2 per2 cep290 cep290 oxr1b oxr1b opn6b opn6b cnga1b cnga1b dgkzb dgkzb got1 got1 pik3r2 pik3r2 pik3r3a pik3r3a mapk6 mapk6 rlbp1a rlbp1a auts2b auts2b junbb junbb hspa5 hspa5 ubl3a ubl3a ctnna1 ctnna1 rims2b rims2b lrp1aa lrp1aa psmd7 psmd7 glula glula crabp2a crabp2a psma1 psma1 eps8a eps8a polr2a polr2a ctsa ctsa cct2 cct2 rtn4b rtn4b ccl34b.1 ccl34b.1 hmgcs1 hmgcs1 sptbn1 sptbn1 pik3ca pik3ca ccl36.1 ccl36.1 kif5aa kif5aa sagb sagb ctnnb1 ctnnb1 top2a top2a Exorh Exorh TULP1 TULP1 ccnd1 ccnd1 capzb capzb ccne2 ccne2 rbp4 rbp4 mesd mesd cct2-2 cct2-2 atf4a atf4a ccna2 ccna2 cxxc5a cxxc5a kras kras park7 park7 gcdha gcdha Aqp9a Aqp9a dscama dscama cngb1a cngb1a gpx4b gpx4b prkcaa prkcaa cry3b cry3b tjp1a tjp1a synpo synpo
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hspd1Heat shock 60kD protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (575 aa)
opn1mw4Green-sensitive opsin-4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (349 aa)
opn1mw1Green-sensitive opsin-1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (349 aa)
nr4a1Nuclear receptor subfamily 4, group A, member 1. (574 aa)
opn1mw3Green-sensitive opsin-3; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (349 aa)
cd74aCD74 molecule, major histocompatibility complex, class II invariant chain a. (237 aa)
ndel1aNuclear distribution protein nudE-like 1-A; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end (By similarity). (344 aa)
cct7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (547 aa)
sirt2NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] (379 aa)
rpl3Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (403 aa)
cct3T-complex protein 1 subunit gamma. (543 aa)
rpl5aRibosomal protein L5a. (297 aa)
psma8Proteasome subunit alpha type. (251 aa)
zap70Tyrosine-protein kinase. (604 aa)
per1bPeriod homolog 1b (Drosophila). (1398 aa)
atp5lATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
pou4f1POU domain protein. (368 aa)
gria1aGlutamate receptor, ionotropic, AMPA 1a. (914 aa)
hsp70.3Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family. (643 aa)
gad2Glutamate decarboxylase 2. (583 aa)
psmc2Proteasome (Prosome, macropain) 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
rhoRhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (354 aa)
psmb1Proteasome subunit beta. (237 aa)
opn1mw2Green-sensitive opsin-2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (349 aa)
slc18a3aProbable vesicular acetylcholine transporter-A; Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. (513 aa)
psmb3Proteasome subunit beta. (205 aa)
rpe65aRetinoid isomerohydrolase; Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). (531 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (661 aa)
snx5Sorting nexin; Involved in several stages of intracellular trafficking. Belongs to the sorting nexin family. (399 aa)
fabp7aFatty acid-binding protein 7, brain, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
snap25aSynaptosomal-associated protein 25-A; May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion; Belongs to the SNAP-25 family. (204 aa)
opn1sw2Opsin-1, short-wave-sensitive 2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (354 aa)
foxn4Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] (550 aa)
hes6Hes family bHLH transcription factor 6. (226 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (466 aa)
fabp11aFatty acid-binding protein H6-isoform; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
stmn1aStathmin; Belongs to the stathmin family. (148 aa)
psmb6Proteasome subunit beta. (232 aa)
cct4T-complex protein 1 subunit delta. (533 aa)
chataCholine O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Belongs to the carnitine/choline acetyltransferase family. (637 aa)
psmd3Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (503 aa)
hmgcl3-hydroxy-3-methylglutaryl-CoA lyase. (340 aa)
rbpms2bRNA-binding protein, mRNA-processing factor 2b. (200 aa)
neurod1Neurogenic differentiation factor 1; May act as a transcriptional activator. Differentiation factor required for neurogenesis. Acts as an upstream activator of isl1. (350 aa)
atp5fa1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
tuba8l4Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
gatad2abGATA zinc finger domain-containing 2Ab. (632 aa)
gsto1Glutathione S-transferase omega 1; Belongs to the GST superfamily. (240 aa)
eno2Eno2 protein. (434 aa)
rprmbProtein reprimo B; May be involved in the regulation of p53-dependent G2 arrest of the cell cycle; Belongs to the reprimo family. (102 aa)
rtn4rReticulon 4 receptor. (479 aa)
foxo3aForkhead box O3A. (643 aa)
aqp1a.1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (260 aa)
ptgdsb.1Lipocalin-type prostaglandin D synthase-like protein; Belongs to the calycin superfamily. Lipocalin family. (184 aa)
grin1bGlutamate receptor, ionotropic, N-methyl D-aspartate 1b. (937 aa)
socs3aSuppressor of cytokine-signaling 3a. (207 aa)
add3aAdducin 3 (gamma) a. (672 aa)
psmb2Proteasome subunit beta. (199 aa)
cacng2aVoltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (324 aa)
pfkfb36-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3. (536 aa)
cx52.6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (474 aa)
dctn2Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity). (405 aa)
ciartaCircadian-associated repressor of transcription a. (358 aa)
ephb2bEph receptor B2b. (989 aa)
gria1bGlutamate receptor, ionotropic, AMPA 1b. (917 aa)
atp2a2bCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1035 aa)
gria3aGlutamate receptor, ionotropic, AMPA 3a. (886 aa)
notch1bNotch receptor 1b. (2465 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (345 aa)
marcksl1bMARCKS-related protein 1-B; Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. (207 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
ccnb2Cyclin B2; Belongs to the cyclin family. (386 aa)
ndufv1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (492 aa)
cd74bCD74 molecule, major histocompatibility complex, class II invariant chain b. (198 aa)
slc3a2bSolute carrier family 3 member 2b. (504 aa)
aurkbAurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] (320 aa)
tubb5Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ndufa6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
her15.1Hairy and enhancer of split-related 15, tandem duplicate 1. (149 aa)
marcksl1aMARCKS-related protein 1-A; Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. (213 aa)
tefaTEF transcription factor, PAR bZIP family member a. (300 aa)
bbs5Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family. (342 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
rgs16Regulator of G protein-signaling 16. (209 aa)
calb2aCalbindin 2, like. (271 aa)
rpl4Ribosomal protein L4. (375 aa)
sdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
cyp51Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. (499 aa)
sesn1Sestrin 1. (488 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
opn1lw1Red-sensitive opsin-1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (357 aa)
rdh10aRetinol dehydrogenase 10-A; Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
cct5Chaperonin-containing TCP1, subunit 5 (epsilon). (541 aa)
opn1sw1Opsin-1, short-wave-sensitive 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (336 aa)
rlbp1bCellular retinaldehyde-binding protein b. (307 aa)
rbpms2aRNA-binding protein, mRNA-processing factor 2a; RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (By similarity). RNA-binding protein localized in Balbiani body (electron-dense aggregates in the oocyte) and germ plasm during oogenesis, and may be required to maintain germ plasm mRNA translational repression. Translational regulator during topographic map formation in the visual system. Establishes oocyte polarity through interaction with Bucky ball (BUC) (Probable). ECO:0000250|UniProtKB:Q9W6I1. (199 aa)
hyal6Hyaluronidase. (486 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
gria2bGlutamate receptor, ionotropic, AMPA 2b. (897 aa)
ppifbPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (192 aa)
hsf2Heat shock transcription factor 2. (489 aa)
slc6a9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (653 aa)
tuba1cTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
nr4a3Nuclear receptor subfamily 4, group A, member 3. (594 aa)
pfkfb4b6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (504 aa)
sik2bSalt-inducible kinase 2b. (896 aa)
prodhaProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (629 aa)
apc2APC regulator of WNT-signaling pathway 2. (2105 aa)
tmco1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (By similarity); Belongs to the TMCO1 family. (188 aa)
per1aPeriod circadian clock 1a. (1352 aa)
rpl6Ribosomal protein L6. (265 aa)
atoh7Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. (134 aa)
camsap1aCalmodulin-regulated spectrin-associated protein 1a. (1458 aa)
gria2aGlutamate receptor, ionotropic, AMPA 2a. (875 aa)
nsfaN-ethylmaleimide-sensitive factor a. (744 aa)
rholRhodopsin. (355 aa)
atp1a3aSodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ptgdsb.2Prostaglandin D2 synthase b, tandem duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (184 aa)
psmc5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa)
adh5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (376 aa)
mycaTranscriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa)
tjp1bTight junction protein 1b; Belongs to the MAGUK family. (1689 aa)
mertkaC-mer proto-oncogene tyrosine kinase a. (952 aa)
chgbChromogranin B. (676 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
lamp2Lysosomal-associated membrane protein 2. (355 aa)
xbp1Transcription factor Treb5. (263 aa)
nrxn3bNeurexin-3b; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. (1687 aa)
pgam1bPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
pfn1Profilin; Belongs to the profilin family. (141 aa)
junbaJunB proto-oncogene, AP-1 transcription factor subunit a. (325 aa)
prdx5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
badaBCL2-associated agonist of cell death a. (145 aa)
dctDopachrome tautomerase. (513 aa)
rac3bRac family small GTPase 3b. (192 aa)
cx52.9Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (476 aa)
psmb7Proteasome subunit beta. (277 aa)
nr1d2bNuclear receptor subfamily 1, group D, member 2b. (578 aa)
cry1aCryptochrome circadian regulator 1a. (619 aa)
calb1Calbindin 1. (260 aa)
atp1b1bSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (317 aa)
cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2196 aa)
nxph2aNeurexophilin; May be signaling molecules that resemble neuropeptides. (267 aa)
grin2aaGlutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1460 aa)
sqstm1Sequestosome 1. (452 aa)
nxnl1Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. Belongs to the nucleoredoxin family. (215 aa)
sagaS-antigen; retina and pineal gland (arrestin) a. (392 aa)
shank2bSH3 and multiple ankyrin repeat domains 2b. (1800 aa)
SDHBSi:dkey-31b16.7. (185 aa)
camsap1bCalmodulin-regulated spectrin-associated protein 1-B; Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and stabilizes microtubules. Acts on free microtubule minus- ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In contrast to camsap2 and camsap3, tracks along the growing tips of minus-end microtubules without significantly affecting the polyme [...] (1558 aa)
rpgrip1RPGR-interacting protein 1. (1342 aa)
eno3Enolase 3, (beta, muscle). (433 aa)
arl13aADP-ribosylation factor-like 13A. (434 aa)
apoc1Apolipoprotein C-I. (85 aa)
dnajb1bDnaJ heat shock protein family (Hsp40) member B1b. (340 aa)
neurod4Neurogenic differentiation factor. (348 aa)
pde6bPhosphodiesterase. (854 aa)
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (790 aa)
tulp1bTUB-like protein 1b; Belongs to the TUB family. (504 aa)
per2Period circadian clock 2. (1399 aa)
cep290Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity and in ciliary targeting of selected BBSome cargos. Required for the correct localization of ciliary and photot [...] (2439 aa)
oxr1bOxidation resistance 1b. (841 aa)
opn6bOpsin 6, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (391 aa)
cnga1bCyclic nucleotide-gated channel subunit alpha 1b. (645 aa)
dgkzbDiacylglycerol kinase. (1057 aa)
got1Aspartate aminotransferase. (410 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
pik3r3aPhosphoinositide-3-kinase, regulatory subunit 3a (gamma). (333 aa)
mapk6Extracellular signal-regulated kinase 3. (729 aa)
rlbp1aRetinaldehyde-binding protein 1a. (312 aa)
auts2bActivator of transcription and developmental regulator AUTS2 b. (748 aa)
junbbJunB proto-oncogene, AP-1 transcription factor subunit b. (310 aa)
hspa5Immunoglobulin binding protein; Belongs to the heat shock protein 70 family. (650 aa)
ubl3aUbiquitin-like protein. (117 aa)
ctnna1Catenin (cadherin-associated protein), alpha 1. (907 aa)
rims2bRegulating synaptic membrane exocytosis 2b. (858 aa)
lrp1aaLow density lipoprotein receptor-related protein 1Aa. (4505 aa)
psmd7Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog). (327 aa)
glulaGlutamine synthetase. (371 aa)
crabp2aCellular retinoic acid binding protein type II; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (142 aa)
psma1Proteasome subunit alpha type. (262 aa)
eps8aEpidermal growth factor receptor pathway substrate 8a. (804 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1965 aa)
ctsaCarboxypeptidase; Belongs to the peptidase S10 family. (471 aa)
cct2Chaperonin-containing TCP1, subunit 2 (beta); Belongs to the TCP-1 chaperonin family. (286 aa)
rtn4bReticulon. (876 aa)
ccl34b.1Chemokine (C-C motif) ligand 34b, duplicate 1. (97 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (519 aa)
sptbn1Spectrin beta chain; Belongs to the spectrin family. (2272 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
ccl36.1C-C motif chemokine. (93 aa)
kif5aaKinesin family member 5A, a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
sagbS-antigen; retina and pineal gland (arrestin) b. (385 aa)
ctnnb1Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1570 aa)
ExorhRhodopsin. (168 aa)
TULP1Tubby-related protein 1-like. (318 aa)
ccnd1G1/S-specific cyclin-D1; May play a role in transcriptional regulation (By similarity). Essential for the control of the cell cycle at the G1/S (start) transition. (291 aa)
capzbF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (392 aa)
rbp4Retinol-binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family. (192 aa)
mesdLRP chaperone MESD; Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway (By similarity). Belongs to the MESD family. (206 aa)
cct2-2Chaperonin-containing TCP1, subunit 2 (beta); Belongs to the TCP-1 chaperonin family. (110 aa)
atf4aCyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. May play a role in the regulation of the circadian clock (By similarity). (339 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (454 aa)
cxxc5aCXXC finger protein 5a. (284 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
park7Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] (189 aa)
gcdhaGlutaryl-Coenzyme A dehydrogenase. (441 aa)
Aqp9aUncharacterized protein. (68 aa)
dscamaDown syndrome cell adhesion molecule a. (2036 aa)
cngb1aCyclic nucleotide-gated channel subunit beta 1a. (822 aa)
gpx4bGlutathione peroxidase; Belongs to the glutathione peroxidase family. (170 aa)
prkcaaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
cry3bCryptochrome circadian regulator 3b. (650 aa)
tjp1aTight junction protein 1a; Belongs to the MAGUK family. (1689 aa)
synpoUncharacterized protein. (873 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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