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adgb adgb myhb myhb invs invs myo3b myo3b myo7ab myo7ab scn8aa scn8aa myo9ab myo9ab myo9aa myo9aa myh11a myh11a camta1b camta1b iqcd iqcd myo1ca myo1ca nrgna nrgna myo6b myo6b MYO1D MYO1D MYO9B MYO9B myo9b myo9b cep131 cep131 rnf32 rnf32 rasgrf2b rasgrf2b rasgrf2a rasgrf2a spata17 spata17 myo10l3 myo10l3 myo18ab myo18ab ube3b ube3b myo5ab myo5ab myh9b myh9b wu:fd14a01 wu:fd14a01 myh7 myh7 LOC556989 LOC556989 iqgap1 iqgap1 spa17 spa17 iqck iqck RASGRF1 RASGRF1 myo7bb myo7bb myhz1.1 myhz1.1 myhc4 myhc4 scn12aa scn12aa myhz2 myhz2 myh6 myh6 iqca1 iqca1 myh7l myh7l iqce iqce myhz1.3 myhz1.3 myo6a myo6a myo3a myo3a mbd3b mbd3b lrriq1 lrriq1 myh14 myh14 myh7bb myh7bb myo16 myo16 myhz1.2 myhz1.2 LOC108190403 LOC108190403 iqch iqch myha myha ube3c ube3c myo10 myo10 myo1hb myo1hb myo1ha myo1ha myo18aa myo18aa myo1b myo1b myo1g myo1g myo15ab myo15ab iqgap2 iqgap2 myo5aa myo5aa zgc:153738 zgc:153738 myh9a myh9a myo15aa myo15aa scn1lab scn1lab myh10 myh10 scn8ab scn8ab myo10l1 myo10l1 camta1a camta1a myo1cb myo1cb cep97 cep97 iqgap3 iqgap3 iqcb1-2 iqcb1-2 iqcb1 iqcb1 myh11b myh11b scn4aa scn4aa iqub iqub Camta2 Camta2 aspm aspm gap43 gap43 scn5lab scn5lab smyhc3 smyhc3 myo5b myo5b smyhc1 smyhc1 LOC100329748 LOC100329748 LOC100329813 LOC100329813 myo5c myo5c smyhc2 smyhc2 myo7aa myo7aa iqcg iqcg ppef1 ppef1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adgbAndroglobin; Belongs to the peptidase C2 family. (1471 aa)
myhbMyosin, heavy chain b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
invsInversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. (1025 aa)
myo3bMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1272 aa)
myo7abMyosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
scn8aaSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1949 aa)
myo9abUnconventional myosin-IXAb; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons (By similarity). Required for the regulation of neurite branching and motor neuron axon guidance. (2286 aa)
myo9aaUnconventional myosin-IXAa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons (By similarity). Required for the regulation of neurite branching and motor neuron axon guidance. (2522 aa)
myh11aMyosin, heavy polypeptide 11, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
camta1bCalmodulin-binding transcription activator 1b. (1626 aa)
iqcdIQ motif-containing D. (402 aa)
myo1caUnconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). (1045 aa)
nrgnaNeurogranin (protein kinase C substrate, RC3) a. (60 aa)
myo6bMyosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1267 aa)
MYO1DUnconventional myosin-Id; Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in the formation of Kupffer's vesicle, an organ that functions as left-right organizer during embryogenesis. Plays a role in vesicular trafficking events that are required for normal lumen expansion of Kupffer's vesicle. Required for normal orientation of cilia in Kupffer's vesicle, and thus for normal, unidirectional circular flow and normal angular flow velocity, which then mediates asymmetric gene expression and left-right asymmetric developm [...] (1004 aa)
MYO9BSi:zfos-588f8.1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2085 aa)
myo9bMyosin IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
cep131Centrosomal protein of 131 kDa; Cilium-specific protein required for the regulation of cilium/flagellum formation. Involved in centriole duplication (By similarity). May play a role in melanosome trafficking ; Belongs to the CEP131 family. (1111 aa)
rnf32Ring finger protein 32. (363 aa)
rasgrf2bRas-specific guanine nucleotide-releasing factor 2; Functions as a calcium-regulated nucleotide exchange factor activating both Ras and rac1 through the exchange of bound GDP for GTP. May function in synaptic plasticity. (1244 aa)
rasgrf2aRas protein-specific guanine nucleotide-releasing factor 2a. (1243 aa)
spata17Spermatogenesis-associated 17. (357 aa)
myo10l3Myosin X,-like 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1537 aa)
myo18abMyosin XVIIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2557 aa)
ube3bUbiquitin protein ligase E3B. (1069 aa)
myo5abMyosin VAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1823 aa)
myh9bMyosin, heavy chain 9b, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1749 aa)
wu:fd14a01Myosin, heavy polypeptide 1.1, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1631 aa)
myh7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
LOC556989Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1124 aa)
iqgap1IQ motif-containing GTPase-activating protein 1. (1655 aa)
spa17Sperm autoantigenic protein 17. (646 aa)
iqckSimilar to IQ motif containing K. (225 aa)
RASGRF1Si:ch211-234p18.3. (1256 aa)
myo7bbMyosin VIIBb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2196 aa)
myhz1.1Myosin, heavy polypeptide 1.1, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
myhc4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
scn12aaSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1932 aa)
myhz2Myosin, heavy polypeptide 2, fast muscle-specific; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
myh6Myosin, heavy chain 6, cardiac muscle, alpha; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
iqca1IQ motif-containing with AAA domain 1. (406 aa)
myh7lMyosin heavy chain 7-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
iqceIQ motif-containing E. (680 aa)
myhz1.3Myosin, heavy polypeptide 1.3, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
myo6aMyosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1288 aa)
myo3aMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1775 aa)
mbd3bMethyl-CpG-binding domain protein 3b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1031 aa)
lrriq1Leucine-rich repeats and IQ motif-containing 1. (1291 aa)
myh14Myosin, heavy chain 14, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2020 aa)
myh7bbMyosin, heavy chain 7B, cardiac muscle, beta b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
myo16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1471 aa)
myhz1.2Myosin, heavy polypeptide 1.2, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
LOC108190403Si:ch73-194h10.2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2220 aa)
iqchIQ motif-containing protein H. (1059 aa)
myhaMyosin, heavy chain a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1933 aa)
ube3cUbiquitin protein ligase E3C. (1081 aa)
myo10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2069 aa)
myo1hbMyosin IHb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (993 aa)
myo1haMyosin IHa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1027 aa)
myo18aaMyosin XVIIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2454 aa)
myo1bMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1107 aa)
myo1gMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (998 aa)
myo15abMyosin XVAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2375 aa)
iqgap2IQ motif-containing GTPase-activating protein 2. (1680 aa)
myo5aaMyosin VAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1890 aa)
zgc:153738Zgc:153738. (357 aa)
myh9aMyosin, heavy chain 9a, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
myo15aaMyosin XVAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (4115 aa)
scn1labSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1996 aa)
myh10Myosin, heavy chain 10, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1992 aa)
scn8abSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1958 aa)
myo10l1Myosin X,-like 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2041 aa)
camta1aCalmodulin-binding transcription activator 1a. (1716 aa)
myo1cbMyosin Ic, paralog b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1028 aa)
cep97Centrosomal protein 97. (599 aa)
iqgap3IQ motif-containing GTPase-activating protein 3. (1639 aa)
iqcb1-2IQ motif-containing B1. (421 aa)
iqcb1IQ motif-containing B1. (595 aa)
myh11bMyosin, heavy chain 11b, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
scn4aaSodium channel protein type 4 subunit alpha A; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles. Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily. (1829 aa)
iqubIQ motif and ubiquitin domain-containing. (750 aa)
Camta2Uncharacterized protein. (330 aa)
aspmAbnormal spindle microtubule assembly. (3391 aa)
gap43Growth-associated protein 43. (194 aa)
scn5labSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1954 aa)
smyhc3Slow myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
myo5bMyosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1839 aa)
smyhc1Slow myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
LOC100329748Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1390 aa)
LOC100329813Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1946 aa)
myo5cMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1746 aa)
smyhc2Slow myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
myo7aaMyosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
iqcgDynein regulatory complex protein 9; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (camk4) activity; contributes to the regulation of camk4 signaling cascades. Plays a role in the regulation of definitive hematopoiesis via its effects on camk4. Belo [...] (346 aa)
ppef1Serine/threonine-protein phosphatase with EF-hands. (729 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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