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| | nr4a1 | Nuclear receptor subfamily 4, group A, member 1. (574 aa) |
| | prkacab | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa) |
| | cdc25b | Cell division cycle 25B. (563 aa) |
| | fgf13b | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (257 aa) |
| | cacna2d4b | Calcium channel, voltage-dependent, alpha 2/delta subunit 4b. (1087 aa) |
| | map3k7 | Mitogen-activated protein kinase kinase kinase 7. (551 aa) |
| | fgf20a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | map2k1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase. (982 aa) |
| | tnfb | Tumor necrosis factor b (TNF superfamily, member 2). (242 aa) |
| | fgf6a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa) |
| | bdnf | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (270 aa) |
| | tnfrsf1a | Tumor necrosis factor receptor superfamily, member 1a. (389 aa) |
| | ppm1bb | Protein phosphatase 1A, magnesium dependent, alpha isoform. (382 aa) |
| | fgfr3 | Fibroblast growth factor receptor 3; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Phosphorylates PLCG1, CBL and FRS2. Ligand binding l [...] (819 aa) |
| | chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. (758 aa) |
| | rras | Related RAS viral (R-ras) oncogene homolog. (196 aa) |
| | map2k2a | Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa) |
| | stk3 | Serine/threonine-protein kinase 3 20kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein stk3/mst2 and stk4/mst1, in complex with its regulatory protein sav1, phosphorylates and activates lats1/2 in complex with its regul [...] (492 aa) |
| | fgf8a | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa) |
| | ntrk1 | Tyrosine-protein kinase receptor. (797 aa) |
| | mapkapk5 | Mitogen-activated protein kinase-activated protein kinase 5. (471 aa) |
| | rap1b | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa) |
| | cacng3a | Calcium channel, voltage-dependent, gamma subunit 3a. (309 aa) |
| | ppp3r1a | Protein phosphatase 3, regulatory subunit B, alpha a. (170 aa) |
| | cacna1c | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2196 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa) |
| | lamtor3 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). (138 aa) |
| | ikbkb | Inhibitor of nuclear factor kappa B kinase subunit beta. (779 aa) |
| | cfap74 | Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (1568 aa) |
| | cacng8a | Calcium channel, voltage-dependent, gamma subunit 8a. (432 aa) |
| | mapk7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1080 aa) |
| | cacng7b | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (373 aa) |
| | rasgrp4 | RAS guanyl-releasing protein 4. (687 aa) |
| | cacna1ia | Calcium voltage-gated channel subunit alpha1 Ia. (2188 aa) |
| | nfkb2 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (902 aa) |
| | ppp3cca | Serine/threonine-protein phosphatase. (499 aa) |
| | cacng6a | Calcium channel, voltage-dependent, gamma subunit 6a. (277 aa) |
| | fgf7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (180 aa) |
| | prkcg | Protein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (654 aa) |
| | cdc42l2 | Cell division cycle 42-like 2. (209 aa) |
| | lrrk2 | Leucine-rich repeat kinase 2. (2532 aa) |
| | tgfb2 | Transforming growth factor, beta 2. (413 aa) |
| | MRAS | Si:ch73-116o1.2. (208 aa) |
| | fgfr2 | Fibroblast growth factor receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in kerati [...] (838 aa) |
| | fgf11b | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa) |
| | ecsit | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B. (452 aa) |
| | egfra | Epidermal growth factor receptor precursor. (625 aa) |
| | map3k2 | Mitogen-activated protein kinase kinase kinase 2. (623 aa) |
| | map3k14a | Mitogen-activated protein kinase kinase kinase 14a. (825 aa) |
| | cacna1ha | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2173 aa) |
| | map4k3b | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (897 aa) |
| | maptb | Microtubule-associated protein. (309 aa) |
| | pla2g4f.1 | Phospholipase A2. (837 aa) |
| | nf1a | Neurofibromin 1a. (2759 aa) |
| | cacng5b | Calcium channel, voltage-dependent, gamma subunit 5b. (275 aa) |
| | relb | V-rel avian reticuloendotheliosis viral oncogene homolog B. (582 aa) |
| | prkcdb | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa) |
| | map3k12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (856 aa) |
| | raf1a | Raf-1 proto-oncogene, serine/threonine kinase a. (654 aa) |
| | mapk8ip1a | Mitogen-activated protein kinase 8-interacting protein 1a. (759 aa) |
| | dusp7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (374 aa) |
| | fgf3 | Fibroblast growth factor 3; Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Belongs to the heparin-binding growth factors family. (256 aa) |
| | fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa) |
| | ENSDARP00000133096 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | rela | V-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa) |
| | dusp2 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (333 aa) |
| | taok2b | TAO kinase 2b. (1121 aa) |
| | grb2a | Growth factor receptor-bound protein 2a. (217 aa) |
| | map3k4 | Mitogen-activated protein kinase kinase kinase 4. (1540 aa) |
| | mapk10 | Mitogen-activated protein kinase. (472 aa) |
| | fgf19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | nfkb1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (540 aa) |
| | fgf4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa) |
| | faslg | Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (268 aa) |
| | map3k1 | Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1334 aa) |
| | pak2a | Non-specific serine/threonine protein kinase. (518 aa) |
| | dusp1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa) |
| | dusp16 | Dual-specificity phosphatase 16. (539 aa) |
| | fgf17 | Fibroblast growth factor 17; Involved in dorsal-ventral embryonic patterning, by promoting expression of bone morphogenetic protein (BMP) antagonists such as chd. Also involved in anterior-posterior neural patterning and in mesoderm induction; Belongs to the heparin-binding growth factors family. (215 aa) |
| | taok1b | TAO kinase 1b. (1001 aa) |
| | prkcab | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (635 aa) |
| | LOC101883703 | PLA2c domain-containing protein. (565 aa) |
| | pdgfab | Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (230 aa) |
| | ntrk2b | Tyrosine-protein kinase receptor. (801 aa) |
| | il1b | Interleukin-1. (284 aa) |
| | il1rl1 | Uncharacterized protein. (342 aa) |
| | hrasa | HRas proto-oncogene, GTPase a. (189 aa) |
| | sos1 | Son of sevenless homolog 1 (Drosophila). (714 aa) |
| | ptprr | Protein tyrosine phosphatase receptor type R. (395 aa) |
| | map2k6 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] (363 aa) |
| | fgfr4 | Fibroblast growth factor receptor 4; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down- regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation o [...] (923 aa) |
| | mapk8a | Mitogen-activated protein kinase. (427 aa) |
| | pdgfba | Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (463 aa) |
| | ENSDARP00000146561 | Si:ch211-1i11.3. (1356 aa) |
| | rasa1b | RAS p21 protein activator (GTPase-activating protein) 1b. (1080 aa) |
| | pdgfrb | Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1072 aa) |
| | rapgef2 | Rap guanine nucleotide exchange factor (GEF) 2. (1619 aa) |
| | mknk2b | MAPK-interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa) |
| | tab2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development. (711 aa) |
| | mapk12b | Mitogen-activated protein kinase. (364 aa) |
| | mapkapk2a | Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily. (382 aa) |
| | cacnb4a | Voltage-gated calcium channel beta-4 subunit variant 2. (519 aa) |
| | akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | stmn1a | Stathmin; Belongs to the stathmin family. (148 aa) |
| | cacna1aa | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2265 aa) |
| | prkacba | Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. (395 aa) |
| | arrb2b | Arrestin, beta 2b. (408 aa) |
| | tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa) |
| | cacna2d1a | Calcium channel, voltage-dependent, alpha 2/delta subunit 1a. (1069 aa) |
| | ikbkg | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (586 aa) |
| | mapk11 | Mitogen-activated protein kinase. (361 aa) |
| | traf6 | TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. (542 aa) |
| | crkl | V-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (305 aa) |
| | mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa) |
| | hsc70 | Heat shock cognate 70; Belongs to the heat shock protein 70 family. (647 aa) |
| | tgfbr2b | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa) |
| | mapk14a | Mitogen-activated protein kinase 14A; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Mapk14a is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are [...] (361 aa) |
| | cacng2a | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (324 aa) |
| | cacna1fb | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa) |
| | fosab | V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (349 aa) |
| | flnca | Filamin C, gamma a (actin-binding protein 280). (2719 aa) |
| | map3k5 | Mitogen-activated protein kinase kinase kinase 5. (1364 aa) |
| | map2k7 | Mitogen-activated protein kinase kinase 7. (438 aa) |
| | braf | B-Raf proto-oncogene, serine/threonine kinase. (817 aa) |
| | fgf10a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa) |
| | gna12a | Guanine nucleotide-binding protein (G protein) alpha 12a. (385 aa) |
| | rap1aa | RAP1A, member of RAS oncogene family a. (185 aa) |
| | fgf5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | map2k5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (450 aa) |
| | nfatc1 | Nuclear factor of-activated T cells 1. (867 aa) |
| | rras2 | Related RAS viral (R-ras) oncogene homolog 2. (202 aa) |
| | nras | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (188 aa) |
| | cacnb1 | Calcium channel, voltage-dependent, beta 1 subunit. (603 aa) |
| | fgf14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa) |
| | hspb1 | Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (199 aa) |
| | tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) |
| | fgf16 | Fibroblast growth factor 16; Plays a crucial role in pectoral fin bud outgrowth. Belongs to the heparin-binding growth factors family. (203 aa) |
| | cacna1sb | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1847 aa) |
| | ppm1ab | Protein phosphatase, Mg2+/Mn2+-dependent, 1Ab. (372 aa) |
| | jun | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa) |
| | gadd45aa | Growth arrest and DNA-damage-inducible, alpha, a. (157 aa) |
| | ngfb | Nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons (By similarity). (194 aa) |
| | rps6ka4 | Ribosomal protein S6 kinase. (745 aa) |
| | LOC405768 | Sterile alpha motif and leucine zipper-containing kinase AZK. (371 aa) |
| | dusp4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | fgf23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (258 aa) |
| | nfatc3a | Nuclear factor of-activated T cells 3a. (1074 aa) |
| | cacng1b | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (228 aa) |
| | dusp10 | Dual-specificity phosphatase 10. (459 aa) |
| | egf | Epidermal growth factor. (1114 aa) |
| | fgfr1b | Fibroblast growth factor receptor. (766 aa) |
| | srfa | Serum response factor a. (539 aa) |
| | casp3b | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (285 aa) |
| | crk | V-crk sarcoma virus CT10 oncogene homolog (Avian). (311 aa) |
| | fas | Fas cell surface death receptor. (293 aa) |
| | mapk13 | Mitogen-activated protein kinase. (362 aa) |
| | rasgrf2a | Ras protein-specific guanine nucleotide-releasing factor 2a. (1243 aa) |
| | ntf3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (243 aa) |
| | ddit3 | DNA-damage-inducible transcript 3. (242 aa) |
| | sos2 | Son of sevenless homolog 2 (Drosophila). (1341 aa) |
| | rps6ka5 | Ribosomal protein S6 kinase. (802 aa) |
| | dusp3a | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa) |
| | map3k8 | Mitogen-activated protein kinase kinase kinase 8. (472 aa) |
| | cacna1bb | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2314 aa) |
| | cacna1e | Calcium channel, voltage-dependent, R type, alpha 1E subunit a. (1793 aa) |
| | mapk8ip2 | Mitogen-activated protein kinase 8-interacting protein 2. (1242 aa) |
| | jund | JunD proto-oncogene, AP-1 transcription factor subunit. (283 aa) |
| | mef2ca | Myocyte enhancer factor 2ca. (465 aa) |
| | pla2g4aa | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. (741 aa) |
| | hspa8 | Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (649 aa) |
| | map4k6 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (889 aa) |
| | mos | V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily. (329 aa) |
| | elk4 | ETS transcription factor ELK4. (443 aa) |
| | mapk3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa) |
| | dusp6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa) |
| | elk1 | ETS transcription factor ELK1. (521 aa) |
| | mapk9 | Mitogen-activated protein kinase. (421 aa) |
| | cacng4b | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (322 aa) |
| | myca | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa) |
| | ptpn5 | Protein tyrosine phosphatase non-receptor type 5. (530 aa) |
| | cacnb3b | Calcium channel, voltage-dependent, beta 3b. (375 aa) |
| | rasgrp3 | RAS guanyl-releasing protein 3 (calcium and DAG-regulated). (708 aa) |
| | fgf22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | RASGRF1 | Si:ch211-234p18.3. (1256 aa) |
| | daxx | Death-domain-associated protein. (716 aa) |
| | arrb1 | Arrestin, beta 1. (418 aa) |
| | map2k4a | Mitogen-activated protein kinase kinase 4A; Belongs to the protein kinase superfamily. (404 aa) |
| | rac1b | Ras-related C3 botulinum toxin substrate 1-like protein. (192 aa) |
| | fgf18a | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ppp5c | Serine/threonine-protein phosphatase. (489 aa) |
| | rac2 | Rac family small GTPase 2. (219 aa) |
| | nlk2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (533 aa) |
| | rac3b | Rac family small GTPase 3b. (192 aa) |
| | mknk1 | MAPK-interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (459 aa) |
| | max | Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor (By similarity). (160 aa) |
| | tgfbr1a | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | akt3b | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | cacna2d2b | Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1056 aa) |
| | taok3b | TAO kinase 3b. (505 aa) |
| | flna | Filamin A, alpha (actin-binding protein 280). (2553 aa) |
