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mmp2 | Matrix metalloproteinase 2. (657 aa) | ||||
cdh11 | Cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (800 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
robo2 | Roundabout, axon guidance receptor, homolog 2 (Drosophila). (1387 aa) | ||||
fgf8a | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa) | ||||
mmp14a | Matrix metallopeptidase 14a (membrane-inserted). (574 aa) | ||||
slc35b2 | Solute carrier family 35, member B2. (435 aa) | ||||
rb1 | Retinoblastoma 1. (903 aa) | ||||
mycbp2 | E3 ubiquitin-protein ligase MYCBP2; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (By similarity). Plays a key role in neural development, probabl [...] (4574 aa) | ||||
pigk | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (389 aa) | ||||
disp1 | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. (1464 aa) | ||||
col4a5 | Collagen, type IV, alpha 5 (Alport syndrome). (1679 aa) | ||||
gdf6a | Growth/differentiation factor 6-A; Growth factor that controls proliferation and cellular differentiation in the retina. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Functions maternally in dorsal/ventral patterning to induce the expression of the zygotic bmp2b and bmp4 genes and ventralize embryos. Zygotic expression does not appear to regulate axis specification, but instead functions to establish the integrity of the axial vessels during embryon [...] (404 aa) | ||||
pax2a | Paired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. (391 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
ext2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa) | ||||
adcy8 | Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (892 aa) | ||||
slc17a6b | Vesicular glutamate transporter 2.1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity. (584 aa) | ||||
alcamb | Activated leukocyte cell adhesion molecule b. (562 aa) | ||||
atoh7 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. (134 aa) | ||||
boc | BOC cell adhesion-associated, oncogene-regulated. (1032 aa) | ||||
dzip1 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. (897 aa) | ||||
col4a6 | Collagen, type IV, alpha 6. (1714 aa) | ||||
top2b | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1618 aa) | ||||
lhx2b | LIM homeobox 2b. (427 aa) | ||||
ahi1 | Abelson helper integration site 1. (1193 aa) | ||||
extl3 | Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (917 aa) | ||||
cyfip2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
gli1 | GLI family zinc finger 1. (1404 aa) | ||||
cpsf1 | Cleavage and polyadenylation-specific factor 1. (1451 aa) | ||||
cdh4 | Cadherin 4, type 1, R-cadherin (retinal); Cadherins are calcium-dependent cell adhesion proteins. (931 aa) | ||||
lama1 | Laminin, alpha 1. (3075 aa) | ||||
fgf19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) | ||||
apc | APC regulator of WNT-signaling pathway. (2754 aa) | ||||
slbp | Stem-loop-binding protein. (302 aa) | ||||
ndr2 | Nodal-related 2. (505 aa) |