STRINGSTRING
gli2a gli2a robo2 robo2 slc35b2 slc35b2 rb1 rb1 lamc1 lamc1 pigk pigk disp1 disp1 ext2 ext2 boc boc dzip1 dzip1 lhx2b lhx2b extl3 extl3 cyfip2 cyfip2 gli1 gli1 lamb1a lamb1a lama1 lama1 slbp slbp ndr2 ndr2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gli2aGLI family zinc finger 2a. (1439 aa)
robo2Roundabout, axon guidance receptor, homolog 2 (Drosophila). (1387 aa)
slc35b2Solute carrier family 35, member B2. (435 aa)
rb1Retinoblastoma 1. (903 aa)
lamc1Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. (1593 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (389 aa)
disp1Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. (1464 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
bocBOC cell adhesion-associated, oncogene-regulated. (1032 aa)
dzip1Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. (897 aa)
lhx2bLIM homeobox 2b. (427 aa)
extl3Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (917 aa)
cyfip2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
gli1GLI family zinc finger 1. (1404 aa)
lamb1aLaminin, beta 1a. (1785 aa)
lama1Laminin, alpha 1. (3075 aa)
slbpStem-loop-binding protein. (302 aa)
ndr2Nodal-related 2. (505 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.