node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
disp1 | dzip1 | ENSDARP00000065230 | ENSDARP00000105423 | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | 0.774 |
disp1 | gli1 | ENSDARP00000065230 | ENSDARP00000129932 | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | GLI family zinc finger 1. | 0.415 |
disp1 | gli2a | ENSDARP00000065230 | ENSDARP00000010693 | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | GLI family zinc finger 2a. | 0.644 |
disp1 | ptch2 | ENSDARP00000065230 | ENSDARP00000071771 | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. | 0.723 |
dzip1 | disp1 | ENSDARP00000105423 | ENSDARP00000065230 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | 0.774 |
dzip1 | gli1 | ENSDARP00000105423 | ENSDARP00000129932 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | GLI family zinc finger 1. | 0.580 |
dzip1 | gli2a | ENSDARP00000105423 | ENSDARP00000010693 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | GLI family zinc finger 2a. | 0.824 |
dzip1 | ptch2 | ENSDARP00000105423 | ENSDARP00000071771 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. | 0.453 |
gli1 | disp1 | ENSDARP00000129932 | ENSDARP00000065230 | GLI family zinc finger 1. | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | 0.415 |
gli1 | dzip1 | ENSDARP00000129932 | ENSDARP00000105423 | GLI family zinc finger 1. | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | 0.580 |
gli1 | gli2a | ENSDARP00000129932 | ENSDARP00000010693 | GLI family zinc finger 1. | GLI family zinc finger 2a. | 0.604 |
gli1 | ptch2 | ENSDARP00000129932 | ENSDARP00000071771 | GLI family zinc finger 1. | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. | 0.979 |
gli2a | disp1 | ENSDARP00000010693 | ENSDARP00000065230 | GLI family zinc finger 2a. | Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (By similarity); Belongs to the dispatched family. | 0.644 |
gli2a | dzip1 | ENSDARP00000010693 | ENSDARP00000105423 | GLI family zinc finger 2a. | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. | 0.824 |
gli2a | gli1 | ENSDARP00000010693 | ENSDARP00000129932 | GLI family zinc finger 2a. | GLI family zinc finger 1. | 0.604 |
gli2a | ptch2 | ENSDARP00000010693 | ENSDARP00000071771 | GLI family zinc finger 2a. | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. | 0.964 |
lama1 | lamb1a | ENSDARP00000135371 | ENSDARP00000131540 | Laminin, alpha 1. | Laminin, beta 1a. | 0.688 |
lama1 | lamc1 | ENSDARP00000135371 | ENSDARP00000024860 | Laminin, alpha 1. | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.740 |
lamb1a | lama1 | ENSDARP00000131540 | ENSDARP00000135371 | Laminin, beta 1a. | Laminin, alpha 1. | 0.688 |
lamb1a | lamc1 | ENSDARP00000131540 | ENSDARP00000024860 | Laminin, beta 1a. | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.937 |