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fam20b | Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases (By similarity). Belongs to the FAM20 family. (409 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) | ||||
panx3 | Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (444 aa) | ||||
tmem165 | GDT1 family protein. (305 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
ihha | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa) | ||||
xylt1 | Xylosyltransferase I. (919 aa) | ||||
gba | Glucosylceramidase. (518 aa) |