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hey2 | Hairy/enhancer-of-split related with YRPW motif protein 2; Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation; Belongs to the HEY family. (324 aa) | ||||
gfi1aa | Growth factor-independent 1A transcription repressor a. (385 aa) | ||||
noto | Notochord homeobox. (241 aa) | ||||
pkd2 | Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel (By similarity). Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades. May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...] (904 aa) | ||||
lbx2 | Ladybird homeobox homolog 2 (Drosophila). (257 aa) | ||||
prrx1a | Paired-related homeobox 1a. (245 aa) | ||||
gdf3 | Protein DVR-1; Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment. (355 aa) | ||||
cftr | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1485 aa) | ||||
DNAH10 | Dynein axonemal heavy chain 10. (4626 aa) | ||||
jam3b | Junctional adhesion molecule 3B; Junctional adhesion protein that mediates heterotypic cell- cell interactions to regulate different cellular processes (By similarity). During myogenesis, it is involved in myocyte fusion through the binding of jam2a on neighboring myocytes. (333 aa) | ||||
rnf115 | Ring finger protein 115. (310 aa) | ||||
galnt11 | Polypeptide N-acetylgalactosaminyltransferase. (590 aa) | ||||
slc25a25b | Calcium-binding mitochondrial carrier protein SCaMC-2-B; Calcium-dependent mitochondrial solute carrier. Belongs to the mitochondrial carrier (TC 2.A.29) family. (524 aa) | ||||
numb | NUMB endocytic adaptor protein. (680 aa) | ||||
pbx4 | Pre-B-cell leukemia transcription factor 4. (343 aa) | ||||
cdx4 | Caudal type homeo box transcription factor 4. (270 aa) | ||||
pacrg | PARK2 co-regulated. (236 aa) | ||||
bmp2b | Bone morphogenetic protein 2b. (411 aa) | ||||
atp6ap1b | ATPase H+-transporting accessory protein 1b. (459 aa) | ||||
tctn2 | Tectonic family member 2. (709 aa) | ||||
wnt8a | Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis; Belongs to the Wnt family. (387 aa) | ||||
atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa) | ||||
cntrob | Centrobin, centrosomal BRCA2-interacting protein. (77 aa) | ||||
mespbb | Mesoderm posterior bb. (244 aa) | ||||
lamb1a | Laminin, beta 1a. (1785 aa) | ||||
scube1 | Signal peptide, CUB domain, EGF-like 1. (1067 aa) | ||||
tbxta | T-box transcription factor T-A; Involved in the transcriptional regulation of genes required for mesoderm differentiation, including itself. Indispensable for the formation of the notochord and the tail structure. Functions together with tbx16/spadetail in development of trunk and tail mesoderm. Functions by itself early in development to repress medial floor plate and promote notochord fate but at later times, functions together with tbx16/spadetail to promote medial floor plate formation. Acts in a parallel pathway to, but cooperates with, non-canonical wnt-signaling during tail form [...] (423 aa) | ||||
mmp21 | Matrix metallopeptidase-21; Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway; Belongs to the peptidase M10A family. (599 aa) | ||||
npas4l | Neuronal PAS domain-containing protein 4-like; Transcription factor specifically expressed in endothelial and hematopoietic precursor cells that acts as a key regulator of the endothelial differentiation cascade. Acts as an early-response transcription factor that regulates the expression of early regulators of endothelial and haematopoietic differentiation, such as etv2 and tal1. (658 aa) | ||||
ripply1 | Protein ripply1; Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites. (140 aa) |