STRINGSTRING
gli2a gli2a barx1 barx1 pitx2 pitx2 ext2 ext2 eda eda clcn7 clcn7 acvr2aa acvr2aa acvr2ba acvr2ba smoc2 smoc2 sp7 sp7 vps4b vps4b edar edar
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gli2aGLI family zinc finger 2a. (1439 aa)
barx1Homeobox protein BarH-like 1; Transcription factor, is involved in craniofacial development, and in stomach organogenesis; Belongs to the BAR homeobox family. (248 aa)
pitx2Pituitary homeobox 2; Isoform a and isoform c differentially regulate mesendoderm formation and asymmetric organ development. Both isoforms regulate left-right development, but isoform a has a stronger effect on heart laterality; Belongs to the paired homeobox family. Bicoid subfamily. (314 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
edaEctodysplasin A; Belongs to the tumor necrosis factor family. (359 aa)
clcn7Chloride channel protein. (795 aa)
acvr2aaSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
acvr2baSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
smoc2SPARC-related modular calcium-binding 2. (437 aa)
sp7Sp7 transcription factor. (528 aa)
vps4bVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (437 aa)
edarEctodysplasin A receptor. (460 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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