node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alkal2a | ltk | ENSDARP00000111041 | ENSDARP00000061546 | ALK and LTK ligand 2a. | Tyrosine-protein kinase receptor. | 0.800 |
csf1ra | gja5b | ENSDARP00000148187 | ENSDARP00000091879 | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.567 |
csf1ra | kcnj13 | ENSDARP00000148187 | ENSDARP00000126942 | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | Potassium inwardly rectifying channel subfamily J member 13. | 0.542 |
csf1ra | mpv17 | ENSDARP00000148187 | ENSDARP00000114374 | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.569 |
gja5b | csf1ra | ENSDARP00000091879 | ENSDARP00000148187 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | 0.567 |
gja5b | igsf11 | ENSDARP00000091879 | ENSDARP00000155976 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Immunoglobulin superfamily member 11. | 0.863 |
gja5b | kcnj13 | ENSDARP00000091879 | ENSDARP00000126942 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Potassium inwardly rectifying channel subfamily J member 13. | 0.834 |
gja5b | mpv17 | ENSDARP00000091879 | ENSDARP00000114374 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.561 |
gja5b | tspan36 | ENSDARP00000091879 | ENSDARP00000032359 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Tetraspanin-36; Plays a role in migration and segregation of pigment cells (melanophores and xanthophores). Contributes to pigment stripe patterning in the epidermis; Belongs to the tetraspanin (TM4SF) family. | 0.462 |
igsf11 | gja5b | ENSDARP00000155976 | ENSDARP00000091879 | Immunoglobulin superfamily member 11. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.863 |
igsf11 | kcnj13 | ENSDARP00000155976 | ENSDARP00000126942 | Immunoglobulin superfamily member 11. | Potassium inwardly rectifying channel subfamily J member 13. | 0.802 |
igsf11 | mpv17 | ENSDARP00000155976 | ENSDARP00000114374 | Immunoglobulin superfamily member 11. | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.485 |
igsf11 | tspan36 | ENSDARP00000155976 | ENSDARP00000032359 | Immunoglobulin superfamily member 11. | Tetraspanin-36; Plays a role in migration and segregation of pigment cells (melanophores and xanthophores). Contributes to pigment stripe patterning in the epidermis; Belongs to the tetraspanin (TM4SF) family. | 0.586 |
kcnj13 | csf1ra | ENSDARP00000126942 | ENSDARP00000148187 | Potassium inwardly rectifying channel subfamily J member 13. | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | 0.542 |
kcnj13 | gja5b | ENSDARP00000126942 | ENSDARP00000091879 | Potassium inwardly rectifying channel subfamily J member 13. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.834 |
kcnj13 | igsf11 | ENSDARP00000126942 | ENSDARP00000155976 | Potassium inwardly rectifying channel subfamily J member 13. | Immunoglobulin superfamily member 11. | 0.802 |
ltk | alkal2a | ENSDARP00000061546 | ENSDARP00000111041 | Tyrosine-protein kinase receptor. | ALK and LTK ligand 2a. | 0.800 |
mpv17 | csf1ra | ENSDARP00000114374 | ENSDARP00000148187 | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] | 0.569 |
mpv17 | gja5b | ENSDARP00000114374 | ENSDARP00000091879 | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.561 |
mpv17 | igsf11 | ENSDARP00000114374 | ENSDARP00000155976 | Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family. | Immunoglobulin superfamily member 11. | 0.485 |