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rpl38 rpl38 bmp7a bmp7a rpl35 rpl35 fgf8a fgf8a rplp2l rplp2l smad1 smad1 pax8 pax8 rps19 rps19 rps3a rps3a smad5 smad5 rps29 rps29 rpl11 rpl11 rplp0 rplp0 sox3 sox3 pax2a pax2a rps8a rps8a rpl36a rpl36a rpl6 rpl6 rps15 rps15 sox2 sox2 chsy1 chsy1 bmp2b bmp2b rps4x rps4x rps15a rps15a tmem67 tmem67 vdrb vdrb rpl35a rpl35a foxi1 foxi1 rpl24 rpl24 rpl28 rpl28 rps3 rps3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
bmp7aBone morphogenetic protein 7a. (432 aa)
rpl3560S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family. (123 aa)
fgf8aFibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa)
rplp2lRibosomal protein, large P2,-like; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
smad1Mothers against decapentaplegic homolog 1; Involved in ventralization. May mediate Bmp2b signaling during embryonic dorsal-ventral pattern formation, and may itself be a transcriptional target for Smad5-mediated Bmp2b signaling. Belongs to the dwarfin/SMAD family. (472 aa)
pax8Paired box 8. (448 aa)
rps19Ribosomal protein S19. (146 aa)
rps3a40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (267 aa)
smad5Mothers against decapentaplegic homolog 5; Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation. Belongs to the dwarfin/SMAD family. (464 aa)
rps29Ribosomal protein S29. (56 aa)
rpl1160S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
rplp060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family. (316 aa)
sox3Transcription factor Sox-3; Transcriptional activator. (300 aa)
pax2aPaired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. (391 aa)
rps8a40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
rpl36a60S ribosomal protein L36a. (106 aa)
rpl6Ribosomal protein L6. (265 aa)
rps15Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
sox2Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). (315 aa)
chsy1Hexosyltransferase. (801 aa)
bmp2bBone morphogenetic protein 2b. (411 aa)
rps4x40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
rps15a40S ribosomal protein S15a; Structural component of the ribosome (By similarity). Required for erythropoiesis during embryonic development. (130 aa)
tmem67Transmembrane protein 67. (982 aa)
vdrbVitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. (422 aa)
rpl35aRibosomal protein L35a. (110 aa)
foxi1Forkhead box I1. (377 aa)
rpl2460S ribosomal protein L24; Plays an essential role in early embryonic development. Belongs to the eukaryotic ribosomal protein eL24 family. (157 aa)
rpl28Ribosomal protein L28. (151 aa)
rps3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (245 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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