node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arl13b | cc2d2a | ENSDARP00000092960 | ENSDARP00000150494 | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | Coiled-coil and C2 domain-containing 2A. | 0.897 |
arl13b | exoc5 | ENSDARP00000092960 | ENSDARP00000124604 | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | Exocyst complex component 5. | 0.542 |
arl13b | rab8a | ENSDARP00000092960 | ENSDARP00000125104 | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | RAB8A, member RAS oncogene family. | 0.807 |
arl13b | rp2 | ENSDARP00000092960 | ENSDARP00000120363 | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane (By similarity). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization (By similarity). In the retina, required for maintenance of rod and cone photoreceptor cells. May have a role in normal retinal localization of the transducins GNB1 and GNAT1, and the rhodopsin kinase GRK1. | 0.484 |
cc2d2a | arl13b | ENSDARP00000150494 | ENSDARP00000092960 | Coiled-coil and C2 domain-containing 2A. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.897 |
cc2d2a | exoc5 | ENSDARP00000150494 | ENSDARP00000124604 | Coiled-coil and C2 domain-containing 2A. | Exocyst complex component 5. | 0.440 |
cc2d2a | eys-2 | ENSDARP00000150494 | ENSDARP00000144515 | Coiled-coil and C2 domain-containing 2A. | Protein eyes shut homolog; Required to maintain the integrity of photoreceptor cells. Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone. Belongs to the EYS family. | 0.440 |
cc2d2a | rab8a | ENSDARP00000150494 | ENSDARP00000125104 | Coiled-coil and C2 domain-containing 2A. | RAB8A, member RAS oncogene family. | 0.894 |
cc2d2a | rp2 | ENSDARP00000150494 | ENSDARP00000120363 | Coiled-coil and C2 domain-containing 2A. | Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane (By similarity). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization (By similarity). In the retina, required for maintenance of rod and cone photoreceptor cells. May have a role in normal retinal localization of the transducins GNB1 and GNAT1, and the rhodopsin kinase GRK1. | 0.587 |
cerkl | eys-2 | ENSDARP00000098560 | ENSDARP00000144515 | Ceramide kinase-like. | Protein eyes shut homolog; Required to maintain the integrity of photoreceptor cells. Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone. Belongs to the EYS family. | 0.745 |
exoc5 | arl13b | ENSDARP00000124604 | ENSDARP00000092960 | Exocyst complex component 5. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.542 |
exoc5 | cc2d2a | ENSDARP00000124604 | ENSDARP00000150494 | Exocyst complex component 5. | Coiled-coil and C2 domain-containing 2A. | 0.440 |
exoc5 | rab8a | ENSDARP00000124604 | ENSDARP00000125104 | Exocyst complex component 5. | RAB8A, member RAS oncogene family. | 0.910 |
eys-2 | cc2d2a | ENSDARP00000144515 | ENSDARP00000150494 | Protein eyes shut homolog; Required to maintain the integrity of photoreceptor cells. Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone. Belongs to the EYS family. | Coiled-coil and C2 domain-containing 2A. | 0.440 |
eys-2 | cerkl | ENSDARP00000144515 | ENSDARP00000098560 | Protein eyes shut homolog; Required to maintain the integrity of photoreceptor cells. Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone. Belongs to the EYS family. | Ceramide kinase-like. | 0.745 |
rab8a | arl13b | ENSDARP00000125104 | ENSDARP00000092960 | RAB8A, member RAS oncogene family. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.807 |
rab8a | cc2d2a | ENSDARP00000125104 | ENSDARP00000150494 | RAB8A, member RAS oncogene family. | Coiled-coil and C2 domain-containing 2A. | 0.894 |
rab8a | exoc5 | ENSDARP00000125104 | ENSDARP00000124604 | RAB8A, member RAS oncogene family. | Exocyst complex component 5. | 0.910 |
rp2 | arl13b | ENSDARP00000120363 | ENSDARP00000092960 | Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane (By similarity). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization (By similarity). In the retina, required for maintenance of rod and cone photoreceptor cells. May have a role in normal retinal localization of the transducins GNB1 and GNAT1, and the rhodopsin kinase GRK1. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.484 |
rp2 | cc2d2a | ENSDARP00000120363 | ENSDARP00000150494 | Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane (By similarity). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization (By similarity). In the retina, required for maintenance of rod and cone photoreceptor cells. May have a role in normal retinal localization of the transducins GNB1 and GNAT1, and the rhodopsin kinase GRK1. | Coiled-coil and C2 domain-containing 2A. | 0.587 |