STRINGSTRING
lft1 lft1 mcamb mcamb net1 net1 pitx2 pitx2 dand5 dand5 hsbp1b hsbp1b coasy coasy ctsba ctsba rpl22l1 rpl22l1 smad2 smad2 cep128 cep128
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lft1Left-right determination factor; Belongs to the TGF-beta family. (358 aa)
mcambMelanoma cell adhesion molecule b. (617 aa)
net1Neuroepithelial cell-transforming 1. (551 aa)
pitx2Pituitary homeobox 2; Isoform a and isoform c differentially regulate mesendoderm formation and asymmetric organ development. Both isoforms regulate left-right development, but isoform a has a stronger effect on heart laterality; Belongs to the paired homeobox family. Bicoid subfamily. (314 aa)
dand5DAN domain family, member 5. (243 aa)
hsbp1bHeat shock factor-binding protein 1b. (76 aa)
coasyCoA synthase. (554 aa)
ctsbaCathepsin B, a; Belongs to the peptidase C1 family. (330 aa)
rpl22l1Ribosomal protein L22-like 1. (126 aa)
smad2Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. (469 aa)
cep128Centrosomal protein 128. (533 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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