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cdh2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
jag2b | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1254 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
pink1 | PTEN-induced kinase 1. (574 aa) | ||||
prdm12b | PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (366 aa) | ||||
bmp7a | Bone morphogenetic protein 7a. (432 aa) | ||||
vldlr | Very low density lipoprotein receptor. (866 aa) | ||||
scn8aa | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1949 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) | ||||
mdga2a | MAM domain-containing glycosylphosphatidylinositol anchor 2a. (957 aa) | ||||
vangl2 | Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] (526 aa) | ||||
sim1a | Single-minded homolog 1-A; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult. (745 aa) | ||||
ift88 | Intraflagellar transport 88 homolog. (824 aa) | ||||
llgl2 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. (1020 aa) | ||||
pax3a | Transcription factor PAX3. (509 aa) | ||||
brd2a | Bromodomain-containing protein 2a. (836 aa) | ||||
dicer1 | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] (1865 aa) | ||||
hdac1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (480 aa) | ||||
cxcl12a | Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) | ||||
marcksl1a | MARCKS-related protein 1-A; Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. (213 aa) | ||||
arl6ip1 | ADP-ribosylation factor-like 6-interacting protein 1. (203 aa) | ||||
olig2 | Oligodendrocyte lineage transcription factor 2. (273 aa) | ||||
cxcr4b | Chemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa) | ||||
ackr3b | Atypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family. (362 aa) | ||||
gdf6a | Growth/differentiation factor 6-A; Growth factor that controls proliferation and cellular differentiation in the retina. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Functions maternally in dorsal/ventral patterning to induce the expression of the zygotic bmp2b and bmp4 genes and ventralize embryos. Zygotic expression does not appear to regulate axis specification, but instead functions to establish the integrity of the axial vessels during embryon [...] (404 aa) | ||||
bves | Blood vessel epicardial substance; Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in skeletal muscle and heart development as well as in the maintenance of heart function. May play a role in vamp3-mediated vesicular transport and recycling of receptor molecules. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. May induce primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)- independent manner. May be involved in epithelial movement during [...] (352 aa) | ||||
ogg1 | 8-oxoguanine DNA glycosylase. (391 aa) | ||||
ctnnd2b | Catenin (cadherin-associated protein), delta 2b. (1210 aa) | ||||
nrg2a | Zgc:162973 protein. (488 aa) | ||||
pbx4 | Pre-B-cell leukemia transcription factor 4. (343 aa) | ||||
meox1 | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] (253 aa) | ||||
her3 | Hairy-related 3. (253 aa) | ||||
ttn.2 | Titin, tandem duplicate 2. (26265 aa) | ||||
ascc1 | Activating signal cointegrator 1 complex subunit 1. (249 aa) | ||||
sox10 | HMG-box transcription factor Sox10. (485 aa) | ||||
hoxb1a | Homeobox protein Hox-B1a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (316 aa) | ||||
her8a | Hairy-related 8a. (221 aa) | ||||
pax5 | Paired box 5. (396 aa) | ||||
ppp1r12a | Protein phosphatase 1 regulatory subunit 12A; Regulates myosin phosphatase activity. (1117 aa) | ||||
prickle1b | Prickle homolog 1b. (863 aa) | ||||
nhsl1b | NHS-like 1b. (1527 aa) | ||||
hnf1ba | Hepatocyte nuclear factor 1-beta-A; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity). Required for induction of rhombomere r5/r6 gene expression in the hindbrain. (555 aa) | ||||
hoxb1b | Homeobox protein Hox-B1b; Sequence-specific transcription factor. Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments; Belongs to the Antp homeobox family. Labial subfamily. (229 aa) | ||||
epb41l5 | Erythrocyte membrane protein band 4.1-like 5. (461 aa) | ||||
cyfip2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa) | ||||
cib2 | Calcium and integrin-binding family member 2. (187 aa) | ||||
znf644b | Zinc finger protein 644b. (1267 aa) | ||||
nrg1 | Neuregulin 1. (730 aa) | ||||
znf644a | Zinc finger protein 644a. (1169 aa) | ||||
tsc2 | TSC complex subunit 2. (1674 aa) | ||||
pcdh10b | Protocadherin 10b. (1026 aa) | ||||
lama1 | Laminin, alpha 1. (3075 aa) | ||||
axin1 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. (835 aa) | ||||
trip4 | Thyroid hormone receptor interactor 4. (564 aa) | ||||
cdh1 | Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa) | ||||
notch1a | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2438 aa) | ||||
dab1a | DAB adaptor protein 1a. (586 aa) | ||||
sox32 | SRY-box transcription factor 32. (307 aa) | ||||
Reln | Reelin domain-containing protein. (259 aa) | ||||
dctn1a | Dynactin 1a. (1257 aa) | ||||
cntn2 | Contactin 2. (1040 aa) | ||||
cc2d2a | Coiled-coil and C2 domain-containing 2A. (1675 aa) | ||||
ndnf | Neuron-derived neurotrophic factor. (585 aa) | ||||
nkx2.2a | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). (273 aa) | ||||
adgrl3.1 | Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family. (1540 aa) |