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gad1a gad1a rimkla rimkla glud1a glud1a gad2 gad2 cps1 cps1 glsb glsb agxtb agxtb adsl adsl got2b got2b adss2 adss2 asrgl1 asrgl1 asl asl glulc glulc got2a got2a agxta agxta aspa aspa got1l1 got1l1 gfpt2 gfpt2 ppat ppat gfpt1 gfpt1 zgc:163121 zgc:163121 gpt2 gpt2 asns asns gad1b gad1b nat8l nat8l aldh5a1 aldh5a1 gls2b gls2b F1R0Q9_DANRE F1R0Q9_DANRE adssl adssl gpt2l gpt2l nit2 nit2 gls2a gls2a glsa glsa abat abat cad cad E7FA20_DANRE E7FA20_DANRE F1QRA1_DANRE F1QRA1_DANRE glsl glsl got1 got1 glula glula ENSDARP00000134476 ENSDARP00000134476 glud1b glud1b adss1 adss1 agxt2 agxt2 glulb glulb zgc:172341 zgc:172341 aldh4a1 aldh4a1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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gad1aGlutamate decarboxylase 1a. (595 aa)
rimklaBeta-citrylglutamate synthase B; Catalyzes the synthesis of beta-citryl-L-glutamate and N- acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate. Belongs to the RimK family. (405 aa)
glud1aGlutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (544 aa)
gad2Glutamate decarboxylase 2. (583 aa)
cps1Carbamoyl-phosphate synthase 1, mitochondrial. (1482 aa)
glsbGlutaminase b. (566 aa)
agxtbSerine--pyruvate aminotransferase. (423 aa)
adslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
got2bAspartate aminotransferase. (428 aa)
adss2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (455 aa)
asrgl1Isoaspartyl peptidase/L-asparaginase alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. (310 aa)
aslArgininosuccinate lyase. (465 aa)
glulcGlutamine synthetase. (371 aa)
got2aAspartate aminotransferase. (428 aa)
agxtaSerine--pyruvate aminotransferase. (391 aa)
aspaAspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (315 aa)
got1l1Glutamic-oxaloacetic transaminase 1-like 1. (423 aa)
gfpt2Glutamine-fructose-6-phosphate transaminase 2. (681 aa)
ppatAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
gfpt1Glutamine--fructose-6-phosphate transaminase 1. (682 aa)
zgc:163121Zgc:163121. (546 aa)
gpt2Glutamic pyruvate transaminase (alanine aminotransferase) 2. (545 aa)
asnsAsparagine synthetase [glutamine-hydrolyzing]. (560 aa)
gad1bGlutamate decarboxylase 1b. (613 aa)
nat8lN-acetylaspartate synthetase; May play a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. May promote dopamine uptake by regulating TNF-alpha expression (By similarity). (282 aa)
aldh5a1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
gls2bGlutaminase 2b (liver, mitochondrial). (627 aa)
F1R0Q9_DANRESi:dkey-103j14.5. (307 aa)
adsslAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (468 aa)
gpt2lAlanine aminotransferase 2-like; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. (562 aa)
nit2Omega-amidase NIT2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha- ketoglutarate and oxaloacetate, respectively. (284 aa)
gls2aGlutaminase 2a (liver, mitochondrial). (605 aa)
glsaGlutaminase a. (591 aa)
abat4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
cadCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2230 aa)
E7FA20_DANRESi:ch211-256m1.8. (1574 aa)
F1QRA1_DANREAmine oxidase. (504 aa)
glslGlutaminase-like. (643 aa)
got1Aspartate aminotransferase. (410 aa)
glulaGlutamine synthetase. (371 aa)
ENSDARP00000134476Si:ch211-217a12.1. (488 aa)
glud1bGlutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
adss1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (456 aa)
agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
glulbGlutamine synthetase. (372 aa)
zgc:172341Zgc:172341. (338 aa)
aldh4a1Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. (556 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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