STRINGSTRING
eno1a eno1a LOC100001620 LOC100001620 pgam1a pgam1a prps1a prps1a pycr3 pycr3 tha1 tha1 pah pah cps1 cps1 tktb tktb aldoaa aldoaa phgdh phgdh psat1 psat1 pfkma pfkma idh1 idh1 rpe rpe got2b got2b idh2 idh2 pfkpa pfkpa eno2 eno2 tpi1a tpi1a asl asl aldoab aldoab glulc glulc aco1 aco1 tkta tkta cbsa cbsa mat2ab mat2ab prps1b prps1b acy1 acy1 arg2 arg2 mat1a mat1a psph psph tpi1b tpi1b got2a got2a gapdh gapdh bcat1 bcat1 pcxb pcxb shmt1 shmt1 pklr pklr got1l1 got1l1 aldob aldob pgk1 pgk1 rpia rpia pgam2 pgam2 aldoca aldoca pfkmb pfkmb pfkla pfkla otc otc mat2al mat2al idh3a idh3a eno4 eno4 idh3g idh3g arg1 arg1 nags nags gpt2 gpt2 pfkpb pfkpb mat2aa mat2aa asns asns pgam1b pgam1b cbsb cbsb eno1b eno1b cth cth cthl cthl eno3 eno3 gpt2l gpt2l bcat2 bcat2 mat2b mat2b aco2 aco2 idh3b idh3b sdsl sdsl got1 got1 pfklb pfklb pcxa pcxa shmt2 shmt2 pycr1a pycr1a glula glula ENSDARP00000134476 ENSDARP00000134476 cs cs glulb glulb aldh18a1 aldh18a1 pkma pkma pycr1b pycr1b taldo1 taldo1 pkmb pkmb aldocb aldocb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
eno1aEnolase 1a, (alpha). (432 aa)
LOC100001620Aminoacylase 1. (420 aa)
pgam1aPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
prps1aPhosphoribosyl pyrophosphate synthetase 1A. (320 aa)
pycr3Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. (288 aa)
tha1Threonine aldolase 1. (413 aa)
pahPhenylalanine hydroxylase. (449 aa)
cps1Carbamoyl-phosphate synthase 1, mitochondrial. (1482 aa)
tktbTransketolase b. (625 aa)
aldoaaFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
psat1Phosphoserine aminotransferase. (368 aa)
pfkmaATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (429 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
got2bAspartate aminotransferase. (428 aa)
idh2Isocitrate dehydrogenase (NADP(+)) 2. (225 aa)
pfkpaATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (787 aa)
eno2Eno2 protein. (434 aa)
tpi1aTriosephosphate isomerase A; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (248 aa)
aslArgininosuccinate lyase. (465 aa)
aldoabFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
glulcGlutamine synthetase. (371 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (890 aa)
tktaTransketolase a. (628 aa)
cbsaCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (571 aa)
mat2abS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (363 aa)
prps1bPhosphoribosyl pyrophosphate synthetase 1B. (318 aa)
acy1Aminoacylase 1. (420 aa)
arg2Arginase. (347 aa)
mat1aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
psphPhosphoserine phosphatase. (249 aa)
tpi1bTriosephosphate isomerase B; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (248 aa)
got2aAspartate aminotransferase. (428 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
bcat1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (385 aa)
pcxbPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1181 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (481 aa)
pklrPyruvate kinase; Belongs to the pyruvate kinase family. (538 aa)
got1l1Glutamic-oxaloacetic transaminase 1-like 1. (423 aa)
aldobFructose-bisphosphate aldolase B; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
pgk1Phosphoglycerate kinase. (417 aa)
rpiaRibose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (275 aa)
pgam2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (255 aa)
aldocaFructose-bisphosphate aldolase C-A. (364 aa)
pfkmbATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (776 aa)
pfklaATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
otcOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (352 aa)
mat2alS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (365 aa)
eno4Enolase 4; Belongs to the enolase family. (576 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (391 aa)
arg1Arginase. (341 aa)
nagsN-acetylglutamate synthase, conserved domain form; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (cps1) activity. Belongs to the acetyltransferase family. (527 aa)
gpt2Glutamic pyruvate transaminase (alanine aminotransferase) 2. (545 aa)
pfkpbATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa)
mat2aaS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
asnsAsparagine synthetase [glutamine-hydrolyzing]. (560 aa)
pgam1bPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
cbsbCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (597 aa)
eno1bEnolase 1b, (alpha). (433 aa)
cthCystathionase (cystathionine gamma-lyase). (404 aa)
cthlCystathionase (cystathionine gamma-lyase),-like. (404 aa)
eno3Enolase 3, (beta, muscle). (433 aa)
gpt2lAlanine aminotransferase 2-like; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. (562 aa)
bcat2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (391 aa)
mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro). (334 aa)
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (790 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
sdslSerine dehydratase-like. (322 aa)
got1Aspartate aminotransferase. (410 aa)
pfklbATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (779 aa)
pcxaPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1181 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (492 aa)
pycr1aPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
glulaGlutamine synthetase. (371 aa)
ENSDARP00000134476Si:ch211-217a12.1. (488 aa)
csCitrate synthase, mitochondrial. (468 aa)
glulbGlutamine synthetase. (372 aa)
aldh18a1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (782 aa)
pkmaPyruvate kinase; Belongs to the pyruvate kinase family. (532 aa)
pycr1bPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (329 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (286 aa)
pkmbPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
aldocbFructose-bisphosphate aldolase C-B. (363 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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