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| | zmat2 | Zinc finger, matrin-type 2. (198 aa) |
| | dhx16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16. (1054 aa) |
| | sart1 | Spliceosome-associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (777 aa) |
| | u2af2a | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (465 aa) |
| | srsf9 | Serine and arginine-rich-splicing factor 9. (245 aa) |
| | sf3a2 | Splicing factor 3a, subunit 2. (278 aa) |
| | rbm22 | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity). Required for normal early embryogenesis. (425 aa) |
| | u2af1 | U2 small nuclear RNA auxiliary factor 1. (250 aa) |
| | rbm25b | RNA-binding motif protein 25b. (830 aa) |
| | sf3b6 | Splicing factor 3b, subunit 6. (125 aa) |
| | sf3b2 | Splicing factor 3b, subunit 2. (825 aa) |
| | ddx23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (807 aa) |
| | xab2 | Similar to Xab2 protein. (851 aa) |
| | snrpc | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa) |
| | hsp70.3 | Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family. (643 aa) |
| | tra2a | Transformer 2 alpha homolog. (297 aa) |
| | snrpd3 | Small nuclear ribonucleoprotein Sm D3. (127 aa) |
| | bud31 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. (144 aa) |
| | tra2b | Transformer 2 beta homolog. (278 aa) |
| | sf3b5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | hnrnpua | Heterogeneous nuclear ribonucleoprotein Ua. (760 aa) |
| | ncbp2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (155 aa) |
| | srsf6b | Serine and arginine-rich-splicing factor 6b. (355 aa) |
| | cwc15 | Protein CWC15 homolog; Involved in pre-mRNA splicing as component of the spliceosome. (244 aa) |
| | sf3b4 | Splicing factor 3b, subunit 4. (400 aa) |
| | snrpb | Small nuclear ribonucleoprotein-associated protein. (239 aa) |
| | u2af2b | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa) |
| | hnrnpa1a | Heterogeneous nuclear ribonucleoprotein A1a. (388 aa) |
| | rbm8a | RNA-binding protein 8A; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain [...] (174 aa) |
| | snrpd1 | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa) |
| | snrpa | Small nuclear ribonucleoprotein polypeptide A. (281 aa) |
| | eftud2 | Elongation factor Tu GTP-binding domain-containing 2. (973 aa) |
| | ccdc12 | Coiled-coil domain-containing 12. (163 aa) |
| | acin1b | Apoptotic chromatin condensation inducer 1b. (1259 aa) |
| | cherp | Calcium homeostasis endoplasmic reticulum protein. (909 aa) |
| | srsf3a | Serine and arginine-rich-splicing factor 3a. (174 aa) |
| | lsm4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (143 aa) |
| | smndc1 | Survival of motor neuron-related-splicing factor 30; Necessary for spliceosome assembly; Belongs to the SMN family. (237 aa) |
| | snu13b | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | snrnp40 | Small nuclear ribonucleoprotein 40 (U5). (347 aa) |
| | hsc70 | Heat shock cognate 70; Belongs to the heat shock protein 70 family. (647 aa) |
| | srsf5a | Serine and arginine-rich-splicing factor 5a. (259 aa) |
| | hspa8b | Si:dkey-4p15.3; Belongs to the heat shock protein 70 family. (647 aa) |
| | rbm17 | RNA-binding motif protein 17. (418 aa) |
| | tcerg1b | Uncharacterized protein. (992 aa) |
| | pqbp1 | Polyglutamine binding protein 1-like. (261 aa) |
| | snrpe | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) |
| | snrnp27 | U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein; May play a role in mRNA splicing. (158 aa) |
| | ddx39b | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B. (435 aa) |
| | hnrnpa1b | Heterogeneous nuclear ribonucleoprotein A1b. (403 aa) |
| | lsm6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation-associated. (80 aa) |
| | plrg1 | Pleiotropic regulator 1. (511 aa) |
| | snrnp70 | Small nuclear ribonucleoprotein 70 (U1). (495 aa) |
| | fus | FUS RNA-binding protein. (541 aa) |
| | ddx5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family. (617 aa) |
| | magoh | Protein mago nashi homolog; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby infl [...] (147 aa) |
| | prpf38a | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. (313 aa) |
| | snrpb2 | Small nuclear ribonucleoprotein polypeptide B2. (220 aa) |
| | snrpd2 | Small nuclear ribonucleoprotein Sm D2. (118 aa) |
| | cdc40 | Cell division cycle 40 homolog (S. cerevisiae). (578 aa) |
| | ppih | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (181 aa) |
| | usp39 | Ubiquitin-specific peptidase 39. (497 aa) |
| | bcas2 | Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. (225 aa) |
| | cdc5l | CDC5 cell division cycle 5-like (S. pombe). (800 aa) |
| | dhx8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1210 aa) |
| | phf5a | PHD finger protein 5A. (110 aa) |
| | prpf38b | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing; Belongs to the PRP38 family. (501 aa) |
| | hnrnpc | Heterogeneous nuclear ribonucleoprotein C. (313 aa) |
| | sf3b1 | Splicing factor 3b, subunit 1. (1315 aa) |
| | thoc3 | THO complex 3. (322 aa) |
| | srsf2a | Serine and arginine-rich-splicing factor 2a. (225 aa) |
| | srsf1a | Serine/arginine-rich splicing factor 1A; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Belongs to the splicing factor SR family. (257 aa) |
| | prpf18 | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. (342 aa) |
| | lsm7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation-associated. (103 aa) |
| | dhx15 | DEAH (Asp-Glu-Ala-His) box helicase 15. (769 aa) |
| | prpf40a | PRP40 pre-mRNA processing factor 40 homolog A (Yeast). (851 aa) |
| | u2surp | U2 snRNP-associated SURP domain-containing. (968 aa) |
| | snu13a | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | isy1 | ISY1-splicing factor homolog. (285 aa) |
| | prpf4 | PRP4 pre-mRNA-processing factor 4 homolog (yeast). (507 aa) |
| | syf2 | Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome. (238 aa) |
| | hspa8 | Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (649 aa) |
| | srsf10b | Serine and arginine-rich-splicing factor 10b. (248 aa) |
| | taf15 | TAF15 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (434 aa) |
| | hnrnpa3 | Heterogeneous nuclear ribonucleoprotein A3. (339 aa) |
| | srsf6a | Serine and arginine-rich-splicing factor 6a. (347 aa) |
| | lsm5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | prpf19 | PRP19/PSO4 homolog (S. cerevisiae). (505 aa) |
| | thoc2 | THO complex 2. (1560 aa) |
| | snrnp200 | Small nuclear ribonucleoprotein 200 (U5). (2134 aa) |
| | snrpd3l | Small nuclear ribonucleoprotein Sm D3. (128 aa) |
| | crnkl1 | Crooked neck pre-mRNA-splicing factor 1. (753 aa) |
| | zgc:163098 | Zgc:163098. (874 aa) |
| | hsp70.2 | Heat shock cognate 70-kd protein, tandem duplicate 2; Belongs to the heat shock protein 70 family. (643 aa) |
| | lsm3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | lsm8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa) |
| | thoc1 | THO complex 1. (655 aa) |
| | prpf3 | PRP3 pre-mRNA-processing factor 3 homolog (yeast). (699 aa) |
| | snrpa1 | Small nuclear ribonucleoprotein polypeptide A. (277 aa) |
| | ddx42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42. (908 aa) |
| | hsp70.1 | Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. (643 aa) |
| | aqr | Aquarius intron-binding spliceosomal factor. (1524 aa) |
| | rbmx | RNA-binding motif protein, X chromosome; RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue- specific regulation of gene transcription and alternative splicing of pre-mRNAs. Associates with chromatin. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Binds non-specifically to pre-mRNAs (By similarity). Required for embryonic development, in particular of the brain. (379 aa) |
| | hnrnpub | Heterogeneous nuclear ribonucleoprotein Ub. (796 aa) |
| | slu7 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. (619 aa) |
| | hspa1b | Si:ch211-199o1.2; Belongs to the heat shock protein 70 family. (639 aa) |
| | hnrpkl | Heterogeneous nuclear ribonucleoprotein K,-like. (431 aa) |
| | srsf1b | Serine/arginine-rich splicing factor 1B; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Belongs to the splicing factor SR family. (245 aa) |
| | acin1a | Apoptotic chromatin condensation inducer 1a. (572 aa) |
| | srsf3b | Serine and arginine-rich-splicing factor 3b. (164 aa) |
| | prpf31 | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. (508 aa) |
| | txnl4a | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | prpf8 | Pre-mRNA-processing factor 8. (2342 aa) |
| | puf60a | Poly-U-binding-splicing factor a. (519 aa) |
| | hnrnpm | Heterogeneous nuclear ribonucleoprotein M. (715 aa) |
| | srsf7a | Serine and arginine-rich-splicing factor 7a. (258 aa) |
| | srsf5b | Serine and arginine-rich-splicing factor 5b. (285 aa) |
| | ppil1 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa) |
| | ppie | Peptidylprolyl isomerase E (cyclophilin E). (333 aa) |
| | srsf2b | Serine and arginine-rich-splicing factor 2b. (220 aa) |
| | srsf4 | Serine and arginine-rich-splicing factor 4. (366 aa) |
| | dhx38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1258 aa) |
| | smx5 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | snrpg | Small nuclear ribonucleoprotein G. (76 aa) |
| | sf3b3 | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] (1217 aa) |
| | snrpf | Small nuclear ribonucleoprotein polypeptide F. (88 aa) |
| | ddx46 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation; Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1018 aa) |
| | eif4a3 | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the [...] (406 aa) |
| | ctnnbl1 | Catenin, beta-like 1. (563 aa) |
| | srsf7b | Serine and arginine-rich-splicing factor 7b. (178 aa) |
| | snw1 | SNW domain-containing 1. (536 aa) |
| | alyref | Aly/REF export factor. (291 aa) |
| | sf3a3 | Splicing factor 3a, subunit 3. (501 aa) |
| | zgc:55733 | Zgc:55733. (289 aa) |
| | hnrnpk | Heterogeneous nuclear ribonucleoprotein K. (429 aa) |
| | prpf6 | PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae). (974 aa) |
| | sf3a1 | Novel protein similar to human splicing factor 3a, subunit 1, 120kD (SF3A1). (780 aa) |
| | puf60b | Poly(U)-binding-splicing factor PUF60-B; DNA- and RNA-binding protein, involved in transcription repression and pre-mRNA splicing. (520 aa) |
