STRINGSTRING
ednraa ednraa prkacab prkacab ppiaa ppiaa ppifa ppifa p2rx2 p2rx2 htr2cl1 htr2cl1 bdkrb1 bdkrb1 F1QPB4_DANRE F1QPB4_DANRE agtr1a agtr1a htr7b htr7b erbb2 erbb2 calm2a calm2a adra1d adra1d camk1gb camk1gb casq1b casq1b stim2b stim2b vdac2 vdac2 mylkb mylkb p2rx3a p2rx3a gnaq gnaq casq2 casq2 adra1ba adra1ba slc25a6 slc25a6 orai1b orai1b cacna1aa cacna1aa prkacba prkacba ppp3ca ppp3ca p2rx5 p2rx5 prkcba prkcba tacr3l tacr3l tnnc1a tnnc1a slc25a4 slc25a4 ppp3cb ppp3cb ryr1b ryr1b itpr1b itpr1b adra1aa adra1aa grin1b grin1b p2rx8 p2rx8 prkcbb prkcbb camk2a camk2a camk1b camk1b cacna1fb cacna1fb atp2a2a atp2a2a atp2a1 atp2a1 gna11b gna11b phkg1a phkg1a plcd1b plcd1b LOC567498 LOC567498 mylka mylka atp2a2b atp2a2b cacna1ba cacna1ba nos2b nos2b oxtr oxtr tacr1a tacr1a trhrb trhrb slc8a4b slc8a4b tnnc1b tnnc1b drd1b drd1b ptk2bb ptk2bb drd6b drd6b adra1bb adra1bb cxcr4b cxcr4b p2rx7 p2rx7 cacna1sb cacna1sb itpka itpka si:dkey-63b1.1 si:dkey-63b1.1 LOC100333270 LOC100333270 oxtrl oxtrl camk1ga camk1ga vdac1 vdac1 gnal gnal avpr1ab avpr1ab CCKAR CCKAR egf egf pdgfc pdgfc ppifb ppifb ltb4r2b ltb4r2b phkg2 phkg2 atp2b1a atp2b1a phka2 phka2 drd7 drd7 grpr grpr htr7a htr7a plcd3b plcd3b ppp3ccb ppp3ccb hrh2b hrh2b cxcr4a cxcr4a plcg2 plcg2 mcoln1b mcoln1b prkacbb prkacbb F2R F2R phka1a phka1a f2r f2r adcy2a adcy2a ptger3 ptger3 pde1a pde1a adcy8 adcy8 slc8a1a slc8a1a cacna1bb cacna1bb cacna1e cacna1e ENSDARP00000086547 ENSDARP00000086547 erbb4a erbb4a atp2b3a atp2b3a lhcgr lhcgr plcb3 plcb3 p2rx4b p2rx4b htr5ab htr5ab adcy1a adcy1a slc8a3 slc8a3 ppp3r1b ppp3r1b phkg1b phkg1b chrm5b chrm5b grin1a grin1a plcd3a plcd3a pdgfra pdgfra grin2ab grin2ab LOC100149482 LOC100149482 tnnc2 tnnc2 atp2b1b atp2b1b camk1db camk1db camk1da camk1da pdgfaa pdgfaa camk2g1 camk2g1 slc25a5 slc25a5 A2CEZ0_DANRE A2CEZ0_DANRE cacna1sa cacna1sa atp2a1l atp2a1l drd1a drd1a ntsr1 ntsr1 calml4a calml4a mcoln3a mcoln3a stim2a stim2a avpr1aa avpr1aa pdgfd pdgfd adcy3a adcy3a si:dkey-1h24.2 si:dkey-1h24.2 mylk3 mylk3 ptger1c ptger1c ptgfr ptgfr phkb phkb Plcb2 Plcb2 erbb3b erbb3b F2R-2 F2R-2 nos2a nos2a adcy1b adcy1b F2R-3 F2R-3 adrb3a adrb3a p2rx4a p2rx4a adrb3b adrb3b camk4 camk4 F2R-4 F2R-4 adrb1 adrb1 F2R-5 F2R-5 stim1a stim1a slc8a1b slc8a1b ednrba ednrba pde1cb pde1cb plce1 plce1 adrb2b adrb2b htr2aa htr2aa grin2ca grin2ca trhr2 trhr2 adora2b adora2b cysltr1 cysltr1 Q5RHR2_DANRE Q5RHR2_DANRE tacr3a tacr3a slc8a4a slc8a4a ppp3r1a ppp3r1a htr6 htr6 mylk2 mylk2 cacna1c cacna1c grin2aa grin2aa E9QFE7_DANRE E9QFE7_DANRE tacr2 tacr2 itpkcb itpkcb slc8a2a slc8a2a tpcn1 tpcn1 mcoln1a mcoln1a cacna1eb cacna1eb p2rx3b p2rx3b si:dkey-28b4.8 si:dkey-28b4.8 camk2d1 camk2d1 itpkca itpkca adcy2b adcy2b ryr1a ryr1a cacna1ia cacna1ia plcg1 plcg1 Chrna11 Chrna11 gna15.4 gna15.4 vdac3 vdac3 orai2 orai2 ppp3cca ppp3cca gna14a gna14a itpkb itpkb grm1a grm1a prkcg prkcg cacna1fa cacna1fa gna15.1 gna15.1 gna14 gna14 erbb3a erbb3a ednrab ednrab ednrbb ednrbb agtr1b agtr1b egfra egfra ighv4-5 ighv4-5 F2R-6 F2R-6 htr2ab htr2ab ptk2ba ptk2ba hrc hrc grin2cb grin2cb chrm3b chrm3b cacna1ha cacna1ha atp2b3b atp2b3b ptafr ptafr calml4b calml4b itpr2 itpr2 mylk4a mylk4a E7FC63_DANRE E7FC63_DANRE chrm3a chrm3a atp2b2 atp2b2 chrm5a chrm5a adrb2a adrb2a htr4 htr4 adra1ab adra1ab Gnal2 Gnal2 ryr3 ryr3 sphk2 sphk2 tacr1b tacr1b tbxa2r tbxa2r stim1b stim1b grm5b grm5b ENSDARP00000132437 ENSDARP00000132437 slc8a2b slc8a2b SPHK1 SPHK1 cacna1ab cacna1ab itpr3 itpr3 mcu mcu tpcn2 tpcn2 PLCB4 PLCB4 htr7c htr7c htr5aa htr5aa casq1a casq1a ryr2b ryr2b chrm2a chrm2a prkacaa prkacaa nos1 nos1 adcy9 adcy9 ptger1b ptger1b cacna1da cacna1da prkcab prkcab Trdn Trdn ENSDARP00000138362 ENSDARP00000138362 cacna1db-3 cacna1db-3 HTR7 HTR7 mcoln2 mcoln2 chrna7 chrna7 pdgfab pdgfab grm1b grm1b LOC101882451 LOC101882451 cysltr3 cysltr3 orai1a orai1a chrm1a chrm1a ltb4r2a ltb4r2a camk2b camk2b plcd4a plcd4a ENSDARP00000144302 ENSDARP00000144302 grm5a grm5a pdgfba pdgfba pdgfbb pdgfbb trhra trhra ENSDARP00000147508 ENSDARP00000147508 htr2b htr2b ENSDARP00000148213 ENSDARP00000148213 camk1a camk1a zgc:56235 zgc:56235 grin2da grin2da MCOLN3 MCOLN3 hrh2a hrh2a itpr1a itpr1a unm_hu7910 unm_hu7910 pdgfrb pdgfrb p2rx1 p2rx1 adora2aa adora2aa plcd1a plcd1a atp2a3 atp2a3 LOC101886891 LOC101886891 prkcaa prkcaa erbb4b erbb4b ptger1a ptger1a CCKBR CCKBR
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ednraaEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (422 aa)
prkacabProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
ppiaaPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
ppifaPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (189 aa)
p2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
htr2cl15-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (518 aa)
bdkrb1Bradykinin receptor B1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
F1QPB4_DANRESi:dkey-247m21.3; Belongs to the G-protein coupled receptor 1 family. (390 aa)
agtr1aAngiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family. (358 aa)
htr7b5-hydroxytryptamine (serotonin) receptor 7b. (369 aa)
erbb2Receptor protein-tyrosine kinase. (1275 aa)
calm2aCalmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
adra1dAdrenoceptor alpha 1D. (491 aa)
camk1gbCalcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily. (433 aa)
casq1bCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (454 aa)
stim2bStromal interaction molecule 2b. (727 aa)
vdac2Voltage-dependent anion channel 2. (283 aa)
mylkbMyosin light chain kinase b. (966 aa)
p2rx3aP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (410 aa)
gnaqGuanine nucleotide-binding protein (G protein), q polypeptide. (359 aa)
casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
adra1baAdrenoceptor alpha 1Ba. (486 aa)
slc25a6Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
orai1bCalcium release-activated calcium channel protein 1; Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores; Belongs to the Orai family. (222 aa)
cacna1aaCalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2265 aa)
prkacbaProtein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. (395 aa)
ppp3caSerine/threonine-protein phosphatase. (521 aa)
p2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (480 aa)
prkcbaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
tacr3lTachykinin receptor 3-like; Belongs to the G-protein coupled receptor 1 family. (395 aa)
tnnc1aTroponin C type 1a (slow). (161 aa)
slc25a4Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ppp3cbSerine/threonine-protein phosphatase. (511 aa)
ryr1bRyanodine receptor 1b (skeletal). (5078 aa)
itpr1bInositol 1,4,5-trisphosphate receptor, type 1b. (2782 aa)
adra1aaAdrenoceptor alpha 1Aa. (485 aa)
grin1bGlutamate receptor, ionotropic, N-methyl D-aspartate 1b. (937 aa)
p2rx8P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
prkcbbProtein kinase C beta type; Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation. Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell survival. Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of card11/carma1, leading to activate the NF-kappa-B signaling. Involved in apoptosis following oxidative damage: in case of oxidative [...] (670 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
camk1bCalcium/calmodulin-dependent protein kinase Ib; Belongs to the protein kinase superfamily. (382 aa)
cacna1fbVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa)
atp2a2aCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
gna11bGuanine nucleotide-binding protein (G protein), alpha 11b (Gq class). (359 aa)
phkg1aPhosphorylase kinase, gamma 1a (muscle); Belongs to the protein kinase superfamily. (394 aa)
plcd1bPhosphoinositide phospholipase C. (749 aa)
LOC567498G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (403 aa)
mylkaMyosin, light chain kinase a. (899 aa)
atp2a2bCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1035 aa)
cacna1baVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2312 aa)
nos2bNitric oxide synthase; Produces nitric oxide (NO). (1077 aa)
oxtrIsotocin receptor-like 2; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (388 aa)
tacr1aNeurokinin 1a receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
trhrbThyrotropin-releasing hormone receptor b; Belongs to the G-protein coupled receptor 1 family. (399 aa)
slc8a4bSolute carrier family 8 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (925 aa)
tnnc1bTroponin C type 1b (slow). (161 aa)
drd1bDopamine receptor D1b; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ptk2bbProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
drd6bDopamine receptor D6b; Belongs to the G-protein coupled receptor 1 family. (426 aa)
adra1bbAdrenoceptor alpha 1Bb. (481 aa)
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
cacna1sbVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1847 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (448 aa)
si:dkey-63b1.1Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
LOC100333270G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (393 aa)
oxtrlIsotocin receptor-like 1. (382 aa)
camk1gaCalcium/calmodulin-dependent protein kinase IGa; Belongs to the protein kinase superfamily. (426 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
gnalGuanine nucleotide-binding protein G(olf) subunit alpha. (379 aa)
avpr1abArginine vasopressin receptor 1Ab. (410 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
egfEpidermal growth factor. (1114 aa)
pdgfcPlatelet-derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (343 aa)
ppifbPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (192 aa)
ltb4r2bLeukotriene B4 receptor 2b. (339 aa)
phkg2Phosphorylase kinase, gamma 2 (testis); Belongs to the protein kinase superfamily. (390 aa)
atp2b1aCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1228 aa)
phka2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1216 aa)
drd7Dopamine receptor D7; Belongs to the G-protein coupled receptor 1 family. (443 aa)
grprGastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (376 aa)
htr7a5-hydroxytryptamine (serotonin) receptor 7a; Belongs to the G-protein coupled receptor 1 family. (479 aa)
plcd3bPhosphoinositide phospholipase C. (769 aa)
ppp3ccbSerine/threonine-protein phosphatase. (506 aa)
hrh2bHistamine receptor H2b; Belongs to the G-protein coupled receptor 1 family. (335 aa)
cxcr4aChemokine (C-X-C motif) receptor 4a; Belongs to the G-protein coupled receptor 1 family. (360 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1240 aa)
mcoln1bMucolipin 1.2. (565 aa)
prkacbbProtein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
F2RSi:dkey-163m14.2. (462 aa)
phka1aPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1219 aa)
f2rCoagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
adcy2aAdenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1151 aa)
ptger3Prostaglandin E receptor 3 (subtype EP3). (401 aa)
pde1aPhosphodiesterase. (611 aa)
adcy8Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (892 aa)
slc8a1aSolute carrier family 8 member 1a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (969 aa)
cacna1bbVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2314 aa)
cacna1eCalcium channel, voltage-dependent, R type, alpha 1E subunit a. (1793 aa)
ENSDARP00000086547Receptor protein-tyrosine kinase. (1392 aa)
erbb4aReceptor protein-tyrosine kinase. (1388 aa)
atp2b3aCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1176 aa)
lhcgrLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (708 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1244 aa)
p2rx4bP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (394 aa)
htr5ab5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b. (346 aa)
adcy1aAdenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
slc8a3Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (917 aa)
ppp3r1bProtein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa)
phkg1bPhosphorylase kinase, gamma 1b (muscle); Belongs to the protein kinase superfamily. (394 aa)
chrm5bMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (457 aa)
grin1aGlutamate receptor, ionotropic, N-methyl D-aspartate 1a. (901 aa)
plcd3a1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores (By similarity). (784 aa)
pdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...] (1456 aa)
grin2abGlutamate receptor, ionotropic, N-methyl D-aspartate 2A, b. (1445 aa)
LOC100149482Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1676 aa)
tnnc2Fast skeletal muscle troponin C. (160 aa)
atp2b1bCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1240 aa)
camk1dbCalcium/calmodulin-dependent protein kinase I delta long; Belongs to the protein kinase superfamily. (392 aa)
camk1daCalcium/calmodulin-dependent protein kinase 1Da; Belongs to the protein kinase superfamily. (433 aa)
pdgfaaPlatelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (194 aa)
camk2g1Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1. (560 aa)
slc25a5Solute carrier family 25 member 5 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
A2CEZ0_DANRESi:dkey-251i10.1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
cacna1saVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1777 aa)
atp2a1lCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (991 aa)
drd1aDopamine receptor D1a; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ntsr1Neurotensin receptor 1 (high affinity); Belongs to the G-protein coupled receptor 1 family. (400 aa)
calml4aCalmodulin-like 4a. (153 aa)
mcoln3aMucolipin 3a. (541 aa)
stim2aTromal interaction molecule 2a. (992 aa)
avpr1aaArginine vasopressin receptor 1Aa; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (379 aa)
pdgfdPlatelet-derived growth factor d. (372 aa)
adcy3aAdenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
si:dkey-1h24.2Si:dkey-1h24.2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
mylk3Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart. (716 aa)
ptger1cProstaglandin E2 receptor subtype EP1-like protein. (376 aa)
ptgfrProstaglandin F receptor (FP); Belongs to the G-protein coupled receptor 1 family. (390 aa)
phkbPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1087 aa)
Plcb2Phosphoinositide phospholipase C. (694 aa)
erbb3bErb-b2 receptor tyrosine kinase 3b. (1429 aa)
F2R-2Si:dkey-163m14.7. (393 aa)
nos2aNitric oxide synthase; Produces nitric oxide (NO). (1079 aa)
adcy1bAdenylate cyclase 1b; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (834 aa)
F2R-3Si:dkey-163m14.4. (438 aa)
adrb3aAdrenoceptor beta 3a; Belongs to the G-protein coupled receptor 1 family. (413 aa)
p2rx4aP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
adrb3bBeta-3-adrenergic receptor b; Belongs to the G-protein coupled receptor 1 family. (405 aa)
camk4Calcium/calmodulin-dependent protein kinase IV; Belongs to the protein kinase superfamily. (364 aa)
F2R-4Si:dkey-163m14.10. (371 aa)
adrb1Adrenergic, beta-1-, receptor. (390 aa)
F2R-5Si:dkey-163m14.6. (411 aa)
stim1aStromal interaction molecule 1a. (676 aa)
slc8a1bSolute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (944 aa)
ednrbaEndothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (426 aa)
pde1cbPhosphodiesterase. (613 aa)
plce1Phospholipase C, epsilon 1. (2248 aa)
adrb2bAdrenoceptor beta 2, surface b. (409 aa)
htr2aa5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (402 aa)
grin2caGlutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1400 aa)
trhr2Novel protein similar to vertebrate thyrotropin-releasing hormone receptor (TRHR); Belongs to the G-protein coupled receptor 1 family. (497 aa)
adora2bAdenosine A2b receptor. (351 aa)
cysltr1Cysteinyl leukotriene receptor 1. (342 aa)
Q5RHR2_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1187 aa)
tacr3aTachykinin receptor 3a; Belongs to the G-protein coupled receptor 1 family. (396 aa)
slc8a4aSodium/calcium exchanger 4 isoform a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (939 aa)
ppp3r1aProtein phosphatase 3, regulatory subunit B, alpha a. (170 aa)
htr65-hydroxytryptamine (serotonin) receptor 6; Belongs to the G-protein coupled receptor 1 family. (472 aa)
mylk2Myosin light chain kinase 2. (777 aa)
cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2196 aa)
grin2aaGlutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1460 aa)
E9QFE7_DANRESi:rp71-17i16.4. (161 aa)
tacr2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
itpkcbKinase; Belongs to the inositol phosphokinase (IPK) family. (474 aa)
slc8a2aSolute carrier family 8 member 2a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (894 aa)
tpcn1Two pore segment channel 1. (805 aa)
mcoln1aMucolipin 1a. (581 aa)
cacna1ebCalcium channel, voltage-dependent, R type, alpha 1E subunit b. (2164 aa)
p2rx3bP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
si:dkey-28b4.8Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1056 aa)
camk2d1Calcium/calmodulin-dependent protein kinase type II delta 1 chain; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system. (476 aa)
itpkcaKinase; Belongs to the inositol phosphokinase (IPK) family. (417 aa)
adcy2bAdenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1139 aa)
ryr1aRyanodine receptor 1a (skeletal). (5062 aa)
cacna1iaCalcium voltage-gated channel subunit alpha1 Ia. (2188 aa)
plcg1Phosphoinositide phospholipase C. (1020 aa)
Chrna11Si:ch211-39a7.1. (589 aa)
gna15.4Guanine nucleotide-binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (361 aa)
vdac3Voltage-dependent anion channel 3. (318 aa)
orai2ORAI calcium release-activated calcium modulator 2. (267 aa)
ppp3ccaSerine/threonine-protein phosphatase. (499 aa)
gna14aGuanine nucleotide-binding protein (G protein), alpha 14a. (365 aa)
itpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (657 aa)
grm1aGlutamate receptor, metabotropic 1a. (1153 aa)
prkcgProtein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (654 aa)
cacna1faVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (659 aa)
gna15.1Guanine nucleotide-binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1. (367 aa)
gna14Guanine nucleotide-binding protein (G protein), alpha 14. (354 aa)
erbb3aErb-b2 receptor tyrosine kinase 3a. (1319 aa)
ednrabEndothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (408 aa)
ednrbbEndothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (365 aa)
agtr1bAngiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (359 aa)
egfraEpidermal growth factor receptor precursor. (625 aa)
ighv4-5Immunoglobulin heavy variable 5-3. (121 aa)
F2R-6Zgc:171965. (391 aa)
htr2ab5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b. (458 aa)
ptk2baProtein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (933 aa)
hrcHistidine-rich calcium-binding protein. (380 aa)
grin2cbUncharacterized protein. (1328 aa)
chrm3bMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (494 aa)
cacna1haVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2173 aa)
atp2b3bCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1180 aa)
ptafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (365 aa)
calml4bCalmodulin-like 4b. (169 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2008 aa)
mylk4aMyosin light chain kinase family, member 4a. (572 aa)
E7FC63_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
chrm3aMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (595 aa)
atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1253 aa)
chrm5aMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (490 aa)
adrb2aAdrenoceptor beta 2, surface a. (405 aa)
htr45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (454 aa)
adra1abAdrenoceptor alpha 1Ab. (431 aa)
Gnal2Uncharacterized protein. (135 aa)
ryr3Ryanodine receptor 3. (4987 aa)
sphk2Sphingosine kinase 2. (869 aa)
tacr1bTachykinin receptor 1b; Belongs to the G-protein coupled receptor 1 family. (412 aa)
tbxa2rThromboxane A2 receptor. (202 aa)
stim1bStromal interaction molecule 1b. (668 aa)
grm5bGlutamate receptor, metabotropic 5b. (1195 aa)
ENSDARP00000132437Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (340 aa)
slc8a2bSodium/calcium exchanger 2 isoform b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (961 aa)
SPHK1Sphingosine kinase 1. (342 aa)
cacna1abCalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. (2319 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2634 aa)
mcuCalcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex). Activity is regulated by micu1 and micu2. At low Ca(2+) levels mcu activity is down-regulated by micu1 and micu2; at higher Ca(2+) levels micu1 increases mcu activity. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Involved in buffe [...] (376 aa)
tpcn2Two pore calcium channel protein 2; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction (By similarity). (774 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1143 aa)
htr7c5-hydroxytryptamine (serotonin) receptor 7c. (400 aa)
htr5aa5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a. (345 aa)
casq1aCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (553 aa)
ryr2bRyanodine receptor 2b (cardiac). (4878 aa)
chrm2aMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (495 aa)
prkacaaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (352 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
adcy9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1364 aa)
ptger1bProstaglandin E receptor 1 subtype EP1a-like protein; Belongs to the G-protein coupled receptor 1 family. (390 aa)
cacna1daVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2082 aa)
prkcabProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (635 aa)
TrdnSi:ch211-199i15.5. (118 aa)
ENSDARP00000138362G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
cacna1db-3Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (207 aa)
HTR75-hydroxytryptamine receptor 7. (410 aa)
mcoln2Mucolipin 2. (434 aa)
chrna7Cholinergic receptor, nicotinic, alpha 7 (neuronal). (510 aa)
pdgfabPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (230 aa)
grm1bGlutamate receptor, metabotropic 1b. (1158 aa)
LOC101882451Uncharacterized protein. (545 aa)
cysltr3Cysteinyl leukotriene receptor 3. (385 aa)
orai1aORAI calcium release-activated calcium modulator 1a. (225 aa)
chrm1aMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (465 aa)
ltb4r2aLeukotriene B4 receptor 2a. (402 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (388 aa)
plcd4aPhosphoinositide phospholipase C. (761 aa)
ENSDARP00000144302Si:ch73-380n15.2. (509 aa)
grm5aGlutamate receptor, metabotropic 5a. (1173 aa)
pdgfbaPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (463 aa)
pdgfbbPlatelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (483 aa)
trhraThyrotropin-releasing hormone receptor a; Belongs to the G-protein coupled receptor 1 family. (397 aa)
ENSDARP00000147508G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (443 aa)
ENSDARP00000148213PH_14 domain-containing protein. (208 aa)
camk1aCalcium/calmodulin-dependent protein kinase Ia; Belongs to the protein kinase superfamily. (386 aa)
zgc:56235Zgc:56235. (281 aa)
grin2daGlutamate receptor, ionotropic, N-methyl D-aspartate 2D, a. (1916 aa)
MCOLN3Mucolipin 3. (595 aa)
hrh2aHistamine receptor H2a; Belongs to the G-protein coupled receptor 1 family. (369 aa)
itpr1aInositol 1,4,5-trisphosphate receptor, type 1a. (2745 aa)
unm_hu7910Un-named hu7910. (600 aa)
pdgfrbPlatelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1072 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
adora2aaAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (442 aa)
plcd1aPhosphoinositide phospholipase C. (781 aa)
atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
LOC101886891Uncharacterized protein. (259 aa)
prkcaaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
erbb4bReceptor protein-tyrosine kinase. (857 aa)
ptger1aProstaglandin E receptor 1a (subtype EP1). (373 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (393 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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