Your Input: | |
| | ppp1caa | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa) |
| | gadd45bb | Growth arrest and DNA-damage-inducible, beta like. (158 aa) |
| | map2k1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa) |
| | foxm1 | Forkhead box M1. (623 aa) |
| | gadd45gb.1 | Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (155 aa) |
| | calm2a | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa) |
| | mycb | Transcriptional regulator Myc-B; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (396 aa) |
| | zfp36l1b | Zinc finger protein 36, C3H type-like 1 like. (348 aa) |
| | mapk12a | Mitogen-activated protein kinase 12; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAP [...] (363 aa) |
| | rras | Related RAS viral (R-ras) oncogene homolog. (196 aa) |
| | vdac2 | Voltage-dependent anion channel 2. (283 aa) |
| | map2k2a | Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa) |
| | atm | Non-specific serine/threonine protein kinase. (3091 aa) |
| | mapkapk2b | MAPK-activated protein kinase 2b; Belongs to the protein kinase superfamily. (397 aa) |
| | hrasb | -Ha-ras Harvey rat sarcoma viral oncogene homolog, like. (189 aa) |
| | fbxw11b | F-box and WD repeat domain-containing 11b. (531 aa) |
| | pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | mapk12b | Mitogen-activated protein kinase. (364 aa) |
| | mapkapk2a | Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily. (382 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (391 aa) |
| | rb1 | Retinoblastoma 1. (903 aa) |
| | slc25a6 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | zgc:55558 | Zgc:55558 protein. (187 aa) |
| | akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | gadd45ga | Growth arrest and DNA-damage-inducible, gamma a. (159 aa) |
| | ppp3ca | Serine/threonine-protein phosphatase. (521 aa) |
| | zfp36l1a | Zinc finger protein 36, C3H type-like 1a. (374 aa) |
| | tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa) |
| | gadd45ba | Growth arrest and DNA-damage-inducible, beta a. (159 aa) |
| | slc25a4 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ppp3cb | Serine/threonine-protein phosphatase. (511 aa) |
| | itpr1b | Inositol 1,4,5-trisphosphate receptor, type 1b. (2782 aa) |
| | ets1 | V-ets avian erythroblastosis virus E26 oncogene homolog 1. (266 aa) |
| | mapk11 | Mitogen-activated protein kinase. (361 aa) |
| | tsc1a | TSC complex subunit 1a. (1128 aa) |
| | mapk14b | Mitogen-activated protein kinase 14B; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Mapk14b is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are [...] (361 aa) |
| | foxo3a | Forkhead box O3A. (643 aa) |
| | chek2 | Checkpoint kinase 2. (503 aa) |
| | ccnd3 | Cyclin D3; Belongs to the cyclin family. (277 aa) |
| | mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa) |
| | tgfbr2b | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa) |
| | pik3r3b | Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma). (464 aa) |
| | mapk14a | Mitogen-activated protein kinase 14A; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Mapk14a is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are [...] (361 aa) |
| | smad3b | Mothers against decapentaplegic homolog. (423 aa) |
| | capn2l | Calpain 2, (m/II) large subunit,-like; Belongs to the peptidase C2 family. (700 aa) |
| | smad3a | Mothers against decapentaplegic homolog. (425 aa) |
| | capn1a | Calpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (704 aa) |
| | zgc:171775 | Mitogen-activated protein kinase. (359 aa) |
| | rbbp4 | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. (424 aa) |
| | cdk21 | Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (305 aa) |
| | nfatc1 | Nuclear factor of-activated T cells 1. (867 aa) |
| | ccnb2 | Cyclin B2; Belongs to the cyclin family. (386 aa) |
| | rras2 | Related RAS viral (R-ras) oncogene homolog 2. (202 aa) |
| | mhc1zba | MHC class I antigen ZBA transcript variant 1; Belongs to the MHC class I family. (398 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (381 aa) |
| | nras | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (188 aa) |
| | pik3r1 | Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa) |
| | e2f5 | E2F transcription factor 5. (363 aa) |
| | rhebl1 | Ras homolog, mTORC1-binding-like 1. (184 aa) |
| | nbn | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity (By similarity). (818 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) |
| | tgfbr1b | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | foxo3b | Forkhead box O3b. (651 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (397 aa) |
| | gadd45aa | Growth arrest and DNA-damage-inducible, alpha, a. (157 aa) |
| | eif4ebp1 | Eukaryotic translation initiation factor 4E-binding protein 1. (120 aa) |
| | vdac1 | Voltage-dependent anion channel 1. (283 aa) |
| | nfatc3a | Nuclear factor of-activated T cells 3a. (1074 aa) |
| | ccnd2a | Cyclin D2, a; Belongs to the cyclin family. (298 aa) |
| | rbl2 | Retinoblastoma-like 2 (p130). (1079 aa) |
| | rbl1 | Retinoblastoma-like 1 (p107). (1058 aa) |
| | F1Q9Z1_DANRE | Si:ch211-202f3.3; Belongs to the peptidase C2 family. (736 aa) |
| | lin37 | Lin-37 DREAM MuvB core complex component. (236 aa) |
| | F1QAH4_DANRE | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (590 aa) |
| | E9QFN0_DANRE | Si:dkeyp-50d11.2; Belongs to the peptidase C2 family. (704 aa) |
| | mdm2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. (475 aa) |
| | capn2b | Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (696 aa) |
| | serpine1 | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (392 aa) |
| | ppp3ccb | Serine/threonine-protein phosphatase. (506 aa) |
| | RASSF5 | Si:dkey-85p17.3. (482 aa) |
| | mapk13 | Mitogen-activated protein kinase. (362 aa) |
| | raf1b | Raf-1 proto-oncogene, serine/threonine kinase b. (629 aa) |
| | foxo1b | Forkhead box protein O1-B; Transcriptional regulator of cell cycle arrest required for cellular stress responses. (629 aa) |
| | hipk2 | Homeodomain-interacting protein kinase 2. (1220 aa) |
| | lin54 | Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA; Belongs to the lin-54 family. (771 aa) |
| | cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (297 aa) |
| | ppp1cab | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (332 aa) |
| | E7F551_DANRE | Si:ch211-160o17.4. (1081 aa) |
| | sirt1 | Sirtuin 1. (710 aa) |
| | LOC100334443 | Sb:cb81. (361 aa) |
| | ppp3r1b | Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa) |
| | ccnd2b | Cyclin D2, b; Belongs to the cyclin family. (295 aa) |
| | mapk3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa) |
| | capn1b | Calpain 1, (mu/I) large subunit b; Belongs to the peptidase C2 family. (700 aa) |
| | slc25a5 | Solute carrier family 25 member 5 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | A2CEZ0_DANRE | Si:dkey-251i10.1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa) |
| | tgfb5 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | LOC571865 | Nuclear factor of-activated T cells 2b. (792 aa) |
| | calml4a | Calmodulin-like 4a. (153 aa) |
| | E7FFJ8_DANRE | Si:ch211-160f23.5. (438 aa) |
| | myca | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa) |
| | zgc:55262 | Zgc:55262; Belongs to the peptidase C2 family. (704 aa) |
| | nfatc4 | Nuclear factor of-activated T cells 4. (865 aa) |
| | ccnb3 | Cyclin B3; Belongs to the cyclin family. (398 aa) |
| | mtor | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa) |
| | ptena | Phosphatase and tensin homolog A; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (467 aa) |
| | smad2 | Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. (469 aa) |
| | ppid | Peptidylprolyl isomerase D (Cyclophilin D). (371 aa) |
| | rheb | Ras homolog, mTORC1-binding. (93 aa) |
| | cdk1 | Cell division control protein 2; Belongs to the protein kinase superfamily. (302 aa) |
| | mybl2b | V-myb avian myeloblastosis viral oncogene homolog-like 2b. (633 aa) |
| | ppp1cb | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | e2f3 | E2F transcription factor 3. (429 aa) |
| | tgfbr1a | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | akt3b | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | zfp36l2 | Zinc finger protein 36, C3H type-like 2. (373 aa) |
| | cdkn1a | Cyclin-dependent kinase inhibitor 1A. (154 aa) |
| | lin52 | Protein lin-52 homolog. (112 aa) |
| | ppp3r1a | Protein phosphatase 3, regulatory subunit B, alpha a. (170 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa) |
| | sqstm1 | Sequestosome 1. (452 aa) |
| | hipk3a | Homeodomain-interacting protein kinase 3a. (1229 aa) |
| | rbb4l | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. (426 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa) |
| | hipk3b | Homeodomain-interacting protein kinase 3b. (1261 aa) |
| | tsc1b | TSC complex subunit 1b. (1228 aa) |
| | nfatc3b | Nuclear factor of-activated T cells 3b. (923 aa) |
| | vdac3 | Voltage-dependent anion channel 3. (318 aa) |
| | ppp3cca | Serine/threonine-protein phosphatase. (499 aa) |
| | trpv4 | Transient receptor potential cation channel, subfamily V, member 4. (856 aa) |
| | rad9b | Cell cycle checkpoint control protein; Belongs to the rad9 family. (402 aa) |
| | tgfb1b | Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa) |
| | zgc:114130 | Zgc:114130. (394 aa) |
| | tgfb2 | Transforming growth factor, beta 2. (413 aa) |
| | MRAS | Si:ch73-116o1.2. (208 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | map2k2b | Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily. (395 aa) |
| | lin9 | Protein lin-9 homolog; Belongs to the lin-9 family. (543 aa) |
| | calml4b | Calmodulin-like 4b. (169 aa) |
| | pik3cb | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1080 aa) |
| | itpr2 | Inositol 1,4,5-trisphosphate receptor, type 2. (2008 aa) |
| | pik3r2 | Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa) |
| | raf1a | Raf-1 proto-oncogene, serine/threonine kinase a. (654 aa) |
| | il6 | Interleukin 6 (interferon, beta 2). (231 aa) |
| | ppp1cbl | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (231 aa) |
| | akt1 | Non-specific serine/threonine protein kinase. (247 aa) |
| | tsc2 | TSC complex subunit 2. (1674 aa) |
| | capn2a | Calpain 2, (m/II) large subunit a; Belongs to the peptidase C2 family. (698 aa) |
| | e2f4 | E2F transcription factor 4. (404 aa) |
| | rela | V-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa) |
| | itpr3 | Inositol 1,4,5-trisphosphate receptor, type 3. (2634 aa) |
| | chek1 | CHK1 checkpoint homolog (S. pombe); Belongs to the protein kinase superfamily. (410 aa) |
| | mcu | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex). Activity is regulated by micu1 and micu2. At low Ca(2+) levels mcu activity is down-regulated by micu1 and micu2; at higher Ca(2+) levels micu1 increases mcu activity. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Involved in buffe [...] (376 aa) |
| | foxo1a | Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye. (652 aa) |
| | igfbp3 | Insulin-like growth factor-binding protein 3. (292 aa) |
| | gata4 | GATA-binding protein 4. (352 aa) |
| | capn8 | Calpain 8; Belongs to the peptidase C2 family. (701 aa) |
| | cxcl19 | Chemokine (C-X-C motif) ligand 19. (101 aa) |
| | nfkb1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (540 aa) |
| | gadd45ab | Growth arrest and DNA-damage-inducible, alpha, b. (156 aa) |
| | cxcl8a | Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa) |
| | e2f1 | E2F transcription factor 1. (429 aa) |
| | cacna1da | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2082 aa) |
| | cacna1db-3 | Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (207 aa) |
| | nfatc2a | Nuclear factor of-activated T cells 2a. (894 aa) |
| | pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | mre11a | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (700 aa) |
| | akt3a | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ccnd1 | G1/S-specific cyclin-D1; May play a role in transcriptional regulation (By similarity). Essential for the control of the cell cycle at the G1/S (start) transition. (291 aa) |
| | akt2l | V-akt murine thymoma viral oncogene homolog 2,-like. (478 aa) |
| | ccne2 | Cyclin E2; Belongs to the cyclin family. (392 aa) |
| | ccne1 | G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition; Belongs to the cyclin family. Cyclin E subfamily. (410 aa) |
| | HUS1B | Checkpoint protein; Belongs to the HUS1 family. (284 aa) |
| | ppp1cc | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa) |
| | hrasa | HRas proto-oncogene, GTPase a. (189 aa) |
| | map2k6 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] (363 aa) |
| | mras | Muscle RAS oncogene homolog. (209 aa) |
| | zgc:56235 | Zgc:56235. (281 aa) |
| | itpr1a | Inositol 1,4,5-trisphosphate receptor, type 1a. (2745 aa) |
