STRINGSTRING
lipA lipA AGB30160.1 AGB30160.1 AGB30161.1 AGB30161.1 AGB30162.1 AGB30162.1 AGB30163.1 AGB30163.1 AGB30361.1 AGB30361.1 AGB30569.1 AGB30569.1 AGB30583.1 AGB30583.1 AGB30712.1 AGB30712.1 AGB31125.1 AGB31125.1 AGB31127.1 AGB31127.1 gcvH gcvH gcvT gcvT AGB31481.1 AGB31481.1 AGB31482.1 AGB31482.1 gdh gdh eno eno tpiA tpiA AGB32088.1 AGB32088.1 AGB32248.1 AGB32248.1 AGB32250.1 AGB32250.1 AGB32308.1 AGB32308.1 thyA thyA folD folD glyA glyA pgk pgk AGB32662.1 AGB32662.1 fbp fbp gpmI gpmI AGB32932.1 AGB32932.1 AGB32999.1 AGB32999.1 AGB33074.1 AGB33074.1 aroA-2 aroA-2 aroB aroB deoC deoC pgi pgi AGB33163.1 AGB33163.1 AGB33200.1 AGB33200.1 AGB33226.1 AGB33226.1 AGB33261.1 AGB33261.1 gap gap AGB33465.1 AGB33465.1 AGB33481.1 AGB33481.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (322 aa)
AGB30160.1PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (369 aa)
AGB30161.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (329 aa)
AGB30162.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme. (546 aa)
AGB30163.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (489 aa)
AGB30361.1Folate-binding protein YgfZ; PFAM: Aminomethyltransferase folate-binding domain; Glycine cleavage T-protein C-terminal barrel domain; TIGRFAM: folate-binding protein YgfZ. (362 aa)
AGB30569.1PFAM: Triosephosphate isomerase. (230 aa)
AGB30583.1Transcriptional regulator/sugar kinase; PFAM: ROK family. (325 aa)
AGB30712.1PFAM: Biotin/lipoate A/B protein ligase family. (278 aa)
AGB31125.1Cytidine deaminase, homotetrameric; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric. (129 aa)
AGB31127.1PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); uridine phosphorylase. (273 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa)
AGB31481.1PFAM: Glycine cleavage system P-protein. (445 aa)
AGB31482.1Glycine cleavage system protein P; PFAM: Aminotransferase class-V. (500 aa)
gdhTheronine dehydrogenase-like Zn-dependent dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway. (374 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa)
AGB32088.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. (403 aa)
AGB32248.1PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (489 aa)
AGB32250.1Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (319 aa)
AGB32308.1PFAM: Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (184 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (338 aa)
folD5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
glyAGlycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
pgkPFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa)
AGB32662.1DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme; PFAM: DeoC/LacD family aldolase. (264 aa)
fbpFructose-1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase. (289 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (524 aa)
AGB32932.1Formyltetrahydrofolate hydrolase; PFAM: ACT domain; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; formyltetrahydrofolate deformylase. (319 aa)
AGB32999.1Putative glycerate kinase; PFAM: MOFRL family. (442 aa)
AGB33074.1Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (339 aa)
aroA-2Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa)
aroBPutative alternative 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (401 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (211 aa)
pgiPFAM: Phosphoglucose isomerase; Belongs to the GPI family. (431 aa)
AGB33163.1glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase. (397 aa)
AGB33200.1Nucleoside-diphosphate-sugar epimerase; Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (257 aa)
AGB33226.1Lipoate-protein ligase A. (235 aa)
AGB33261.1PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); uridine phosphorylase. (242 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. (337 aa)
AGB33465.1Threonine aldolase; PFAM: Beta-eliminating lyase. (338 aa)
AGB33481.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (484 aa)
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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