Your Input: | |
| | purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (196 aa) |
| | AGB32299.1 | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) |
| | AGB32308.1 | PFAM: Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (184 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (338 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (449 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa) |
| | AGB32417.1 | Hypothetical protein. (150 aa) |
| | AGB32425.1 | Uncharacterized protein, putative amidase; PFAM: Creatinine amidohydrolase. (256 aa) |
| | AGB32429.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (383 aa) |
| | AGB32432.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (381 aa) |
| | tfe | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] (174 aa) |
| | AGB32484.1 | acetate--CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase. (659 aa) |
| | AGB32486.1 | acetate--CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase. (666 aa) |
| | AGB32504.1 | precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. (344 aa) |
| | AGB32505.1 | precorrin-3B methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. (290 aa) |
| | AGB32506.1 | Cobalamin biosynthesis protein CbiG; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal. (329 aa) |
| | AGB32507.1 | Precorrin-4 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase. (306 aa) |
| | AGB32508.1 | Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (267 aa) |
| | AGB32509.1 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit. (201 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (456 aa) |
| | AGB32515.1 | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. (269 aa) |
| | AGB32516.1 | PFAM: Precorrin-8X methylmutase. (249 aa) |
| | AGB32517.1 | PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit. (1298 aa) |
| | AGB32518.1 | PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain. (746 aa) |
| | AGB32537.1 | NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. (283 aa) |
| | AGB32551.1 | Hypothetical protein; PFAM: CbiX. (299 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (454 aa) |
| | AGB32578.1 | DNA polymerase elongation subunit (family B); PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region. (1321 aa) |
| | AGB32589.1 | Putative sugar kinase; PFAM: ATP-NAD kinase. (267 aa) |
| | thi4 | Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (309 aa) |
| | ctaB-2 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (473 aa) |
| | AGB32654.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (381 aa) |
| | AGB32677.1 | PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. (396 aa) |
| | AGB32684.1 | Hypothetical protein; PFAM: ATP-NAD kinase. (379 aa) |
| | AGB32686.1 | PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (227 aa) |
| | AGB32689.1 | PFAM: 6-pyruvoyl tetrahydropterin synthase. (159 aa) |
| | queE | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (262 aa) |
| | queC | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (242 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (210 aa) |
| | AGB32718.1 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (577 aa) |
| | rpoP | DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (44 aa) |
| | guaAA | GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit; Catalyzes the synthesis of GMP from XMP. (184 aa) |
| | AGB32802.1 | PRPP-binding protein, adenine/guanine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (189 aa) |
| | AGB32804.1 | PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic. (390 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (140 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, PurK protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (385 aa) |
| | purE | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (213 aa) |
| | AGB32865.1 | acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. (676 aa) |
| | AGB32873.1 | Putative phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. (232 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (481 aa) |
| | tmk | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. (201 aa) |
| | cofG | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (386 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (339 aa) |
| | AGB32929.1 | Molybdopterin converting factor, small subunit; PFAM: ThiS family. (90 aa) |
| | AGB32932.1 | Formyltetrahydrofolate hydrolase; PFAM: ACT domain; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; formyltetrahydrofolate deformylase. (319 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (83 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (225 aa) |
| | AGB32943.1 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; uncharacterized domain 2. (583 aa) |
| | AGB32955.1 | PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal. (92 aa) |
| | AGB32993.1 | PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain. (172 aa) |
| | AGB33001.1 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. (560 aa) |
| | AGB33002.1 | PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa) |
| | AGB33022.1 | PFAM: RNA polymerases M/15 Kd subunit; Transcription factor S-II (TFIIS); TIGRFAM: transcription factor S, archaeal; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (102 aa) |
| | AGB33027.1 | Hypothetical protein. (167 aa) |
| | AGB33029.1 | NTP pyrophosphohydrolase; PFAM: NUDIX domain. (146 aa) |
| | AGB33037.1 | Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (393 aa) |
| | AGB33048.1 | Aminodeoxychorismate synthase, component I, clade 2; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, clade 2. (534 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (280 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (421 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (312 aa) |
| | tfb-6 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (326 aa) |
| | mfnA | Tyrosine decarboxylase MnfA; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (361 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (561 aa) |
| | guaAB | GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit; Catalyzes the synthesis of GMP from XMP. (305 aa) |
| | AGB33131.1 | PFAM: 5-formyltetrahydrofolate cyclo-ligase family. (242 aa) |
| | AGB33132.1 | Molybdopterin biosynthesis enzyme; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (188 aa) |
| | carA | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (359 aa) |
| | AGB33173.1 | PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. (346 aa) |
| | AGB33197.1 | Uncharacterized protein, putative amidase; PFAM: Creatinine amidohydrolase. (245 aa) |
| | mptD | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (118 aa) |
| | AGB33205.1 | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (241 aa) |
| | AGB33211.1 | PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (194 aa) |
| | AGB33214.1 | Histones H3 and H4; PFAM: Histone-like transcription factor (CBF/NF-Y) and archaeal histone. (143 aa) |
| | AGB33218.1 | Nicotinic acid phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain. (387 aa) |
| | AGB33229.1 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (271 aa) |
| | AGB33231.1 | Aspartate oxidase; PFAM: domain; FAD binding domain. (506 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (377 aa) |
| | AGB33242.1 | Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. (147 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (264 aa) |
| | tfb-7 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (321 aa) |
| | nadK | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa) |
| | AGB33281.1 | Hypothetical protein. (252 aa) |
| | mptA | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (308 aa) |
| | AGB33290.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (387 aa) |
| | AGB33294.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (379 aa) |
| | AGB33306.1 | Anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase. (355 aa) |
| | AGB33314.1 | Hypothetical protein. (310 aa) |
| | AGB33317.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (406 aa) |
| | AGB33339.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (398 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (459 aa) |
| | nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (141 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (398 aa) |
| | AGB33394.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (975 aa) |
| | AGB33395.1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (609 aa) |
| | AGB33396.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; Belongs to the RNA polymerase beta chain family. (526 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H, RpoH/RPB5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (75 aa) |
| | tfb-8 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (308 aa) |
| | AGB33459.1 | Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain. (105 aa) |
| | thiM | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (276 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa) |
| | AGB33525.1 | PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (527 aa) |
| | AGB33526.1 | PFAM: Aminotransferase class-III; TIGRFAM: 2,4-diaminobutyrate 4-transaminases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | AGB33531.1 | Uncharacterized protein, putative amidase; PFAM: Creatinine amidohydrolase. (257 aa) |
| | AGB33545.1 | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (337 aa) |
| | hemL | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (448 aa) |
| | AGB33552.1 | PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase. (379 aa) |
| | AGB33553.1 | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. (265 aa) |
| | hemD-2 | PFAM: Uroporphyrinogen-III synthase HemD. (246 aa) |
| | AGB33563.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa) |
| | polC | DNA polymerase type II, large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1720 aa) |
| | AGB33585.1 | Putative Zn-finger containing protein; PFAM: Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27). (239 aa) |
| | AGB33596.1 | Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain. (232 aa) |
| | thiI | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (392 aa) |
| | AGB33601.1 | Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. (464 aa) |
| | AGB33605.1 | NCAIR mutase-like protein; PFAM: AIR carboxylase. (252 aa) |
| | ribL-2 | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (163 aa) |
| | AGB32291.1 | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative. (180 aa) |
| | pyrB | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. (314 aa) |
| | pyrI | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (162 aa) |
| | AGB32278.1 | PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB. (183 aa) |
| | hemA-2 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (433 aa) |
| | AGB32259.1 | Protein with phosphotransacetylase BioD-like N-terminal domain; PFAM: DRTGG domain. (381 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. (330 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (714 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (476 aa) |
| | tfb-5 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (341 aa) |
| | AGB32163.1 | PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases. (447 aa) |
| | rpoL | DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (94 aa) |
| | AGB32105.1 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. (397 aa) |
| | mptE | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (235 aa) |
| | lig | ATP-dependent DNA ligase I; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (577 aa) |
| | AGB32052.1 | Putative nucleoside kinase, CMP and AMP kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (190 aa) |
| | cmk-2 | Cytidylate kinase, putative; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: cytidylate kinase, putative. (203 aa) |
| | guaB | Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa) |
| | tfb-4 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (324 aa) |
| | AGB31988.1 | PFAM: Cytochrome oxidase assembly protein. (292 aa) |
| | AGB31945.1 | Molybdopterin converting factor, small subunit; PFAM: ThiS family. (136 aa) |
| | ribL | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (142 aa) |
| | AGB31893.1 | PFAM: Transcription factor S-II (TFIIS); TIGRFAM: transcription factor S, archaeal; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (109 aa) |
| | dbh | nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (436 aa) |
| | AGB31877.1 | DNA-directed RNA polymerase, subunit M/transcription elongation factor TFIIS; PFAM: RNA polymerases M/15 Kd subunit. (105 aa) |
| | AGB31875.1 | DNA polymerase IV (family X); PFAM: PHP domain. (583 aa) |
| | AGB31800.1 | Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (370 aa) |
| | AGB31762.1 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (545 aa) |
| | AGB31757.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (374 aa) |
| | tbp-2 | TATA-box binding protein (TBP), component of TFIID and TFIIIB; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (186 aa) |
| | pdxS-2 | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (299 aa) |
| | hemD | PFAM: Uroporphyrinogen-III synthase HemD. (245 aa) |
| | AGB31682.1 | acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. (655 aa) |
| | AGB31673.1 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; PFAM: Transcription factor TFIIB repeat. (274 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa) |
| | rpoK | DNA-directed RNA polymerase, subunit K/omega; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | rpoN | DNA-directed RNA polymerase, subunit N (RpoN/RPB10); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (64 aa) |
| | rpoD | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (249 aa) |
| | moaA | Putative molybdenum cofactor biosynthesis protein A, archaeal; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (338 aa) |
| | priS | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] (391 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (270 aa) |
| | AGB31539.1 | Orotate phosphoribosyltransferase-like enzyme; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (217 aa) |
| | tfb-3 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (320 aa) |
| | AGB31485.1 | PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase. (177 aa) |
| | AGB31458.1 | Putative nuleotide-utilizing enzyme, moeA; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (249 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (228 aa) |
| | AGB31452.1 | 7-keto-8-aminopelargonate synthetase-like enzyme; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase. (407 aa) |
| | bioB | Biotin synthase-like enzyme; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (367 aa) |
| | AGB31392.1 | Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (397 aa) |
| | AGB31361.1 | Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (382 aa) |
| | AGB31321.1 | Hypothetical protein; PFAM: RNA polymerase Rpb4. (118 aa) |
| | AGB31302.1 | PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain. (170 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (503 aa) |
| | AGB31238.1 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. (356 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (456 aa) |
| | tfb-2 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (319 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (535 aa) |
| | AGB31148.1 | PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase. (229 aa) |
| | AGB31140.1 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. (221 aa) |
| | AGB31132.1 | PFAM: Cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain. (155 aa) |
| | AGB31131.1 | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; PFAM: Transcription factor TFIIB repeat. (102 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (169 aa) |
| | tfb | Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (325 aa) |
| | AGB31084.1 | PFAM: Ribonucleotide reductase, small chain. (299 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (355 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (218 aa) |
| | trpE | Anthranilate synthase component I, archaeal clade; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate a [...] (560 aa) |
| | AGB31060.1 | PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (215 aa) |
| | AGB31014.1 | PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (336 aa) |
| | cobS | Cobalamin 5''-phosphate synthase/cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (259 aa) |
| | AGB31007.1 | GTP:adenosylcobinamide-phosphate guanylyltransferase. (195 aa) |
| | AGB31006.1 | TIGR00303 family protein; PFAM: Phosphoribosyltransferase; TIGRFAM: TIGR00303 family protein; Belongs to the UPF0284 family. (342 aa) |
| | AGB31005.1 | PLP-dependent enzyme, histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase. (349 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (204 aa) |
| | AGB30934.1 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (239 aa) |
| | ribK | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (235 aa) |
| | AGB30906.1 | Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (429 aa) |
| | AGB30866.1 | PFAM: Protein of unknown function DUF137. (259 aa) |
| | AGB30864.1 | Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain. (275 aa) |
| | cmk | PFAM: Adenylate kinase; TIGRFAM: cytidylate kinase, putative. (192 aa) |
| | adk | Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (445 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (280 aa) |
| | pyrF | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. (265 aa) |
| | AGB30707.1 | PRPP-binding protein, adenine/guanine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. (246 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (174 aa) |
| | AGB30686.1 | 4-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa) |
| | AGB30605.1 | PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: guanosine monophosphate reductase, eukaryotic. (381 aa) |
| | AGB30563.1 | Hypothetical protein. (309 aa) |
| | AGB30543.1 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; dihydropteroate synthase. (839 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1058 aa) |
| | pdxS | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (302 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (478 aa) |
| | AGB30502.1 | TIGRFAM: siroheme synthase, N-terminal domain. (217 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa) |
| | phhB | PFAM: Pterin 4 alpha carbinolamine dehydratase. (93 aa) |
| | AGB30477.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (189 aa) |
| | AGB30475.1 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. (189 aa) |
| | AGB30471.1 | Metal-dependent hydrolase, beta-lactamase superfamily I. (274 aa) |
| | AGB30452.1 | 4-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; TIGRFAM: 2,4-diaminobutyrate 4-transaminases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | AGB30451.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (389 aa) |
| | AGB30445.1 | Deoxycytidine deaminase; PFAM: dUTPase. (160 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (383 aa) |
| | AGB30389.1 | Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain. (434 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (292 aa) |
| | AGB30373.1 | Molybdopterin converting factor, large subunit; PFAM: MoaE protein. (278 aa) |
| | pyrH | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | AGB30367.1 | Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase. (495 aa) |
| | AGB30337.1 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (201 aa) |
| | tfx | PFAM: Sigma-70, region 4; TIGRFAM: DNA-binding protein, Tfx family. (178 aa) |
| | atpE | Archaeal/vacuolar-type H+-ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (193 aa) |
| | atpC | ATP synthase A1, C subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (355 aa) |
| | atpF | Archaeal/vacuolar-type H+-ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (110 aa) |
| | atpA | ATP synthase, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (587 aa) |
| | atpB | ATP synthase, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (469 aa) |
| | atpD | H(+)-transporting ATP synthase, vacuolar type, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (237 aa) |
| | AGB30289.1 | PRPP-binding protein, adenine/guanine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (181 aa) |
| | AGB30272.1 | NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase. (296 aa) |
| | AGB30247.1 | acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (569 aa) |
| | pdxT | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (205 aa) |
| | AGB30177.1 | Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain. (121 aa) |
| | AGB30160.1 | PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (369 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (322 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (363 aa) |
| | tbp | TATA-box binding protein (TBP), component of TFIID and TFIIIB; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (186 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (285 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (225 aa) |
| | polB | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (523 aa) |
