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nrdR | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (162 aa) | ||||
EHM01466.1 | Protein hit; KEGG: lsl:LSL_0477 3.4e-48 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) K02503; Psort location: Cytoplasmic, score: 9.26. (144 aa) | ||||
EHM01232.1 | Hydrolase, NUDIX family; KEGG: hsl:OE1648R 1.3e-14 apa; putative bis(5'-nucleosyl)-tetraphosphatase (asymmetrical). (143 aa) | ||||
EHM01233.1 | Guanylate kinase; KEGG: lme:LEUM_1839 9.3e-55 guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. (185 aa) | ||||
guaA | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. (538 aa) | ||||
EHM01269.1 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (287 aa) | ||||
EHM00937.1 | KEGG: lbr:LVIS_0449 1.3e-87 exopolyphosphatase; K01514 exopolyphosphatase; Psort location: Cytoplasmic, score: 9.97. (313 aa) | ||||
EHM00952.1 | KEGG: lsg:lse_0169 1.7e-78 purR; Pur operon transcriptional repressor K09685; Psort location: Cytoplasmic, score: 9.97. (280 aa) | ||||
prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) | ||||
EHM00857.1 | Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; KEGG: lac:LBA0041 0. ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.96. (757 aa) | ||||
EHM00863.1 | KEGG: lhe:lhv_1918 7.9e-81 adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96. (185 aa) | ||||
prs-2 | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa) | ||||
EHM00743.1 | KEGG: lbr:LVIS_1439 9.7e-60 NUDIX family hydrolase; K01515 ADP-ribose pyrophosphatase. (180 aa) | ||||
EHM00769.1 | RelA/SpoT domain protein; KEGG: lpj:JDM1_1860 4.9e-81 GTP pyrophosphokinase (putative); K07816 putative GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (217 aa) | ||||
EHM00478.1 | Phosphopentomutase; KEGG: lsa:LSA0796 8.4e-35 deoB; phosphopentomutase K01839; Psort location: Cytoplasmic, score: 8.96. (278 aa) | ||||
EHM00481.1 | Putative cytidine/uridine-specific hydrolase; KEGG: lbr:LVIS_2069 1.1e-131 ribonucleoside hydrolase RihC; K01239 purine nucleosidase; Psort location: Cytoplasmic, score: 8.96. (305 aa) | ||||
ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) | ||||
EHM00491.1 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (383 aa) | ||||
EHM00398.1 | Lyase; KEGG: stc:str1345 1.0e-151 purB2; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97. (434 aa) | ||||
EHM00243.1 | Putative pyrimidine-specific ribonucleoside hydrolase RihB; KEGG: lpl:lp_2591 8.1e-111 purine nucleosidase K01239. (323 aa) | ||||
EHM00263.1 | LysM domain protein; KEGG: lfe:LAF_1820 2.3e-13 hypothetical protein; K01185 lysozyme; Psort location: Extracellular, score: 9.65. (207 aa) | ||||
guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (323 aa) | ||||
purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) | ||||
EHM00272.1 | Adenylosuccinate lyase; KEGG: lpj:JDM1_2623 2.7e-174 purB; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97. (431 aa) | ||||
EHM00162.1 | Putative guanine deaminase; KEGG: lca:LSEI_1136 1.2e-43 cytosine/adenosine deaminase; K01487 guanine deaminase; Psort location: Cytoplasmic, score: 9.26. (160 aa) | ||||
EHM00197.1 | Macro domain protein; KEGG: noc:Noc_1830 7.5e-21 Appr-1-p processing; Psort location: Cytoplasmic, score: 8.96. (264 aa) | ||||
EHM00079.1 | Phosphopentomutase; KEGG: lcb:LCABL_25260 1.1e-92 deoB; phosphopentomutase K01839; Psort location: Cytoplasmic, score: 9.26. (401 aa) | ||||
EHM00098.1 | Class I glutamine amidotransferase; KEGG: lsl:LSL_0339 7.2e-71 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.26. (232 aa) | ||||
EHL99725.1 | KEGG: lbr:LVIS_2142 2.0e-137 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (518 aa) | ||||
EHL99328.1 | Ser/Thr phosphatase family protein; KEGG: lpl:lp_3251 3.4e-57 3',5'-cyclic-nucleotide phosphodiesterase K01120; Psort location: Cytoplasmic, score: 9.97. (313 aa) | ||||
adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) | ||||
truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (268 aa) | ||||
xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa) | ||||
EHL99219.1 | ATP-grasp domain protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (386 aa) | ||||
EHL99273.1 | Hypothetical protein; KEGG: tbd:Tbd_2668 4.7e-29 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: CytoplasmicMembrane, score: 10.00. (369 aa) | ||||
EHL99055.1 | Deoxyguanosine kinase; KEGG: lbr:LVIS_1520 1.5e-93 deoxynucleoside kinase; K00904 deoxyguanosine kinase. (217 aa) | ||||
EHL98560.1 | Amidase, hydantoinase/carbamoylase family; KEGG: bcl:ABC3738 4.8e-74 pucH; allantoate amidohydrolase K02083. (405 aa) | ||||
EHL98576.1 | Putative nrdI protein; KEGG: sds:SDEG_0228 3.1e-31 nrdI; flavoprotein NrdI K03647; Psort location: Cytoplasmic, score: 8.96; Belongs to the NrdI family. (151 aa) | ||||
EHL98578.1 | Hypothetical protein; KEGG: hpa:HPAG1_1423 3.4e-48 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 10.00. (474 aa) | ||||
EHL98517.1 | EDD domain protein, DegV family; KEGG: mga:MGA_1184 2.0e-12 DegV-like protein. (287 aa) | ||||
EHL98518.1 | Putative phosphoglucomutase; KEGG: lbr:LVIS_1907 3.1e-205 phosphomannomutase; K01835 phosphoglucomutase; Psort location: Cytoplasmic, score: 9.97. (581 aa) | ||||
EHL98521.1 | EDD domain protein, DegV family. (280 aa) | ||||
EHL98266.1 | TIGR00730 family protein; KEGG: mct:MCR_0842 1.7e-32 putative lysine decarboxylase K06966; Belongs to the LOG family. (194 aa) | ||||
allB | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. (461 aa) | ||||
EHL97998.1 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (284 aa) | ||||
EHL98021.1 | RelA/SpoT domain protein; KEGG: bde:BDP_1431 5.8e-46 relA2; relA2 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (230 aa) | ||||
EHL98034.1 | KEGG: ppe:PEPE_0484 0. anaerobic ribonucleoside triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97. (726 aa) | ||||
EHL97899.1 | Hypothetical protein; KEGG: lbu:LBUL_1272 2.9e-32 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase; K01081 5'-nucleotidase. (206 aa) | ||||
tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (466 aa) | ||||
EHL97842.1 | KEGG: lbr:LVIS_0522 1.0e-62 hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) | ||||
EHL97518.1 | Hydrolase, NUDIX family; KEGG: lpj:JDM1_2216 6.0e-44 ADP-ribose pyrophosphatase; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 9.97; Belongs to the Nudix hydrolase family. (183 aa) | ||||
EHL97361.1 | Hypothetical protein; KEGG: stc:str1345 1.7e-32 purB2; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.26. (213 aa) | ||||
EHL97362.1 | Hypothetical protein; KEGG: bcg:BCG9842_B4374 0.00071 purB_1; adenylosuccinate lyase K01857. (55 aa) | ||||
EHL97346.1 | Hypothetical protein. (57 aa) | ||||
EHL97263.1 | Hypothetical protein; KEGG: ldb:Ldb1363 4.3e-50 putative secreted 5'-nucleotidase K01081; Psort location: Periplasmic, score: 9.44. (291 aa) | ||||
apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) | ||||
EHL96839.1 | EDD domain protein, DegV family; KEGG: mga:MGA_1184 5.3e-16 DegV-like protein. (288 aa) | ||||
EHL96803.1 | Hypothetical protein; KEGG: tbd:Tbd_2668 0.00064 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: CytoplasmicMembrane, score: 10.00. (320 aa) | ||||
EHL96713.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (248 aa) | ||||
EHL96641.1 | KEGG: lbr:LVIS_0595 3.7e-147 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526. (318 aa) | ||||
EHL96642.1 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (721 aa) | ||||
tadA | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (157 aa) | ||||
EHL96286.1 | Phage hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (122 aa) | ||||
EHL96188.1 | Phage hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (131 aa) | ||||
gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa) | ||||
EHL95873.1 | EDD domain protein, DegV family; KEGG: mga:MGA_1184 1.4e-19 DegV-like protein; Psort location: Cytoplasmic, score: 8.96. (301 aa) | ||||
EHL95912.1 | EDD domain protein, DegV family; KEGG: mga:MGA_1184 1.8e-14 DegV-like protein; Psort location: Cytoplasmic, score: 8.96. (282 aa) | ||||
EHL95917.1 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (296 aa) | ||||
EHL95919.1 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) | ||||
EHL95934.1 | Pyruvate kinase; KEGG: lbr:LVIS_0765 7.0e-263 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 9.97. (607 aa) | ||||
EHL95962.1 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (291 aa) | ||||
EHL95969.1 | RelA/SpoT family protein; KEGG: lbr:LVIS_0728 1.9e-166 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (443 aa) | ||||
EHL95970.1 | HD domain protein; KEGG: lbr:LVIS_0728 2.1e-121 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (295 aa) | ||||
EHL95798.1 | Ser/Thr phosphatase family protein; KEGG: ldb:Ldb1591 1.1e-108 putative 5'-nucleotidase K01081; Belongs to the 5'-nucleotidase family. (463 aa) | ||||
EHL95578.1 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (201 aa) | ||||
EHL95406.1 | Deoxyguanosine kinase; KEGG: lbr:LVIS_1711 5.3e-75 deoxynucleoside kinase; K00904 deoxyguanosine kinase. (212 aa) | ||||
EHL95119.1 | Lyase; KEGG: stc:str1345 2.2e-62 purB2; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97. (459 aa) | ||||
EHL95121.1 | Macro domain protein; KEGG: noc:Noc_1830 1.8e-44 Appr-1-p processing. (168 aa) | ||||
EHL95168.1 | Hypothetical protein; KEGG: lpl:lp_0843 1.2e-47 ppx3; exopolyphosphatase K01514. (227 aa) | ||||
EHL95169.1 | Hypothetical protein; KEGG: lpl:lp_0843 7.1e-80 ppx3; exopolyphosphatase K01514; Psort location: Cytoplasmic, score: 9.97. (278 aa) | ||||
EHL95171.1 | KEGG: lpl:lp_0841 1.3e-96 ppx2; exopolyphosphatase K01514; Psort location: Cytoplasmic, score: 9.26. (316 aa) | ||||
purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) | ||||
EHL95217.1 | Putative phosphoribosylaminoimidazole carboxylase, ATPase subunit; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (273 aa) | ||||
EHL95218.1 | Hypothetical protein; KEGG: lpj:JDM1_2187 1.1e-44 purK1; phosphoribosylaminoimidazole carboxylase ATPase subunit; K01589 5-(carboxyamino)imidazole ribonucleotide synthase. (109 aa) | ||||
purC | KEGG: lpj:JDM1_2186 5.9e-76 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the SAICAR synthetase family. (246 aa) | ||||
purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (87 aa) | ||||
purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (228 aa) | ||||
purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (744 aa) | ||||
EHL95223.1 | Amidophosphoribosyltransferase; KEGG: lpl:lp_2723 2.0e-162 purF; amidophosphoribosyltransferase K00764; Psort location: Cytoplasmic, score: 9.97. (407 aa) | ||||
purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: lpl:lp_2722 4.4e-103 purM; phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 9.97. (336 aa) | ||||
purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (185 aa) | ||||
purH | KEGG: lpl:lp_2720 1.5e-191 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 9.97. (509 aa) | ||||
purD | KEGG: lpl:lp_2719 3.5e-110 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family. (414 aa) |