STRINGSTRING
C02F5.7 C02F5.7 Gyc88E-5 Gyc88E-5 CSKR_8584s CSKR_8584s PDE7A PDE7A CLF_105967 CLF_105967 Hint2 Hint2 mggB mggB Papss2 Papss2 nft-1 nft-1 ADCY9-2 ADCY9-2 PDE2A-2 PDE2A-2 PGM2 PGM2 Nudt9-2 Nudt9-2 PNP-2 PNP-2 CLF_109024 CLF_109024 AK3 AK3 CSKR_9377s CSKR_9377s PDE8B PDE8B PNP PNP AK6 AK6 apt apt ENTPD1 ENTPD1 Pde4d-2 Pde4d-2 NT5C3A NT5C3A Ampd2 Ampd2 dlg1 dlg1 slc37a3 slc37a3 Enpp5-2 Enpp5-2 AK9 AK9 GMPS GMPS Prps1 Prps1 slc37a2 slc37a2 Smarca1 Smarca1 CSKR_13342s CSKR_13342s Rrm1 Rrm1 adcy9 adcy9 Pde4d Pde4d ADK ADK yfkN yfkN TTLL5 TTLL5 Adcy1 Adcy1 pde-5 pde-5 rut rut MPP5 MPP5 PDE2A PDE2A NME1 NME1 AK7 AK7 Gyc88E Gyc88E NME7 NME7 HGPRT HGPRT ENTPD6 ENTPD6 PDE6D PDE6D Rep Rep Pde9a Pde9a ADCY9 ADCY9 CSKR_4115s CSKR_4115s Gyc88E-2 Gyc88E-2 enpp4 enpp4 PUS1 PUS1 Nudt9 Nudt9 dlg1-2 dlg1-2 Kdm1b Kdm1b PGM1 PGM1 ntp-1 ntp-1 Nudt16 Nudt16 Mpp2 Mpp2 MPP6 MPP6 rrm2 rrm2 dnc dnc Gyc88E-3 Gyc88E-3 Cnnm2 Cnnm2 Gucy2f Gucy2f AK9-2 AK9-2 AK7-2 AK7-2 ADCY3 ADCY3 NTPCR NTPCR PyK PyK Pde11 Pde11 Ampd2-2 Ampd2-2 ADA ADA ADA-2 ADA-2 PUS3 PUS3 slc37a2-2 slc37a2-2 Ppp1r8 Ppp1r8 CSKR_13842s CSKR_13842s Guk1 Guk1 CSKR_3180s CSKR_3180s dom-2 dom-2 HGPRT-2 HGPRT-2 Ak5 Ak5 Gyc32E Gyc32E ttll3 ttll3 SVOP SVOP gcy-28 gcy-28 Npr1 Npr1 PRPSAP2 PRPSAP2 CSKR_8834s CSKR_8834s PKM PKM AK8 AK8 CHD1L CHD1L ADAL ADAL nme6 nme6 punA punA FBXL2 FBXL2 NME5 NME5 Pde1c Pde1c SVOP-2 SVOP-2 Pde4b Pde4b PDE9A PDE9A HGPRT-3 HGPRT-3 IPO13 IPO13 TTLL1 TTLL1 Cnnm2-2 Cnnm2-2 PRUNE PRUNE CSKR_1558s CSKR_1558s IMPDH2 IMPDH2 Gyc88E-4 Gyc88E-4 adk adk Ttll10 Ttll10 NT5C3A-2 NT5C3A-2 Nt5c2 Nt5c2 Cask Cask Ampd2-3 Ampd2-3 Mpp7 Mpp7 dlg1-3 dlg1-3 ADSL ADSL NPR1 NPR1 Pde9a-2 Pde9a-2 Hells Hells Guk1-2 Guk1-2 CSKR_6392s CSKR_6392s
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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C02F5.7Putative F-box/LRR-repeat-like protein. (557 aa)
Gyc88E-5Soluble guanylate cyclase 88E. (687 aa)
CSKR_8584sAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (516 aa)
PDE7AHigh affinity cAMP-specific 3' 5'-cyclic phosphodiesterase 7A; Belongs to the cyclic nucleotide phosphodiesterase family. (670 aa)
CLF_105967Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa)
Hint2Histidine triad nucleotide-binding protein 2 mitochondrial. (165 aa)
mggBTrifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family. (596 aa)
Papss2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (617 aa)
nft-1Bis(5'-adenosyl)-triphosphatase. (493 aa)
ADCY9-2Adenylate cyclase type 9. (1198 aa)
PDE2A-2Phosphodiesterase. (944 aa)
PGM2Phosphoglucomutase-2; Belongs to the phosphohexose mutase family. (529 aa)
Nudt9-2ADP-ribose pyrophosphatase. (299 aa)
PNP-2Purine nucleoside phosphorylase. (330 aa)
CLF_109024Adenylate kinase; Belongs to the adenylate kinase family. (198 aa)
AK3GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (228 aa)
CSKR_9377sSCHIP-1 domain-containing protein. (674 aa)
PDE8BHigh affinity cAMP-specific and IBMX-insensitive 3. (482 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (293 aa)
AK6Adenylate kinase isoenzyme 6. (131 aa)
aptAdenine phosphoribosyltransferase. (137 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (399 aa)
Pde4d-2Phosphodiesterase. (574 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (354 aa)
Ampd2AMP deaminase 2. (655 aa)
dlg1Disks large 1 tumor suppressor protein. (552 aa)
slc37a3Sugar phosphate exchanger 3. (478 aa)
Enpp5-2Ectonucleotide pyrophosphatase/phosphodiesterase family member 5. (525 aa)
AK9Adenylate kinase 9. (1835 aa)
GMPSGMP synthase [glutamine-hydrolyzing]. (563 aa)
Prps1Ribose-phosphate pyrophosphokinase 1. (695 aa)
slc37a2Sugar phosphate exchanger 2. (482 aa)
Smarca1Putative global transcription activator SNF2L1. (1001 aa)
CSKR_13342sUncharacterized protein. (290 aa)
Rrm1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (840 aa)
adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1125 aa)
Pde4dPhosphodiesterase. (502 aa)
ADKAdenosine kinase. (369 aa)
yfkNTrifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family. (563 aa)
TTLL5Tubulin polyglutamylase TTLL5. (1506 aa)
Adcy1Adenylate cyclase type 1. (1083 aa)
pde-5Phosphodiesterase. (797 aa)
rutCa(2+)/calmodulin-responsive adenylate cyclase. (3335 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (1152 aa)
PDE2APhosphodiesterase. (656 aa)
NME1Nucleoside diphosphate kinase A; Belongs to the NDK family. (118 aa)
AK7Adenylate kinase 7. (672 aa)
Gyc88ESoluble guanylate cyclase 88E. (936 aa)
NME7Nucleoside diphosphate kinase 7. (286 aa)
HGPRTHypoxanthine-guanine phosphoribosyltransferase. (406 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (618 aa)
PDE6DRetinal rod rhodopsin-sensitive cGMP 3. (66 aa)
RepRab proteins geranylgeranyltransferase component A. (958 aa)
Pde9aHigh affinity cGMP-specific 3; Belongs to the cyclic nucleotide phosphodiesterase family. (308 aa)
ADCY9Adenylate cyclase type 9. (1119 aa)
CSKR_4115sF-box domain-containing protein. (901 aa)
Gyc88E-2Soluble guanylate cyclase 88E. (670 aa)
enpp4Bis(5'-adenosyl)-triphosphatase enpp4. (713 aa)
PUS1tRNA pseudouridine synthase A. (432 aa)
Nudt9ADP-ribose pyrophosphatase. (247 aa)
dlg1-2Disks large 1 tumor suppressor protein. (367 aa)
Kdm1bLysine-specific histone demethylase 1B. (1314 aa)
PGM1Phosphoglucomutase-1. (615 aa)
ntp-1Nucleoside-triphosphatase ntp-1; Belongs to the GDA1/CD39 NTPase family. (414 aa)
Nudt16U8 snoRNA-decapping enzyme. (171 aa)
Mpp2MAGUK p55 subfamily member 2. (939 aa)
MPP6MAGUK p55 subfamily member 6; Belongs to the MAGUK family. (519 aa)
rrm2Ribonucleoside-diphosphate reductase subunit M2. (366 aa)
dncPhosphodiesterase. (460 aa)
Gyc88E-3Soluble guanylate cyclase 88E. (877 aa)
Cnnm2Metal transporter CNNM2. (725 aa)
Gucy2fGuanylate cyclase. (2232 aa)
AK9-2Adenylate kinase 9. (207 aa)
AK7-2Adenylate kinase 7. (816 aa)
ADCY3Adenylate cyclase type 3. (1105 aa)
NTPCRCancer-related nucleoside-triphosphatase-like protein. (230 aa)
PyKPyruvate kinase; Belongs to the pyruvate kinase family. (570 aa)
Pde11Phosphodiesterase. (870 aa)
Ampd2-2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (833 aa)
ADAAdenosine deaminase. (127 aa)
ADA-2Adenosine deaminase. (340 aa)
PUS3tRNA pseudouridine(38/39) synthase. (506 aa)
slc37a2-2Sugar phosphate exchanger 2. (322 aa)
Ppp1r8Nuclear inhibitor of protein phosphatase 1. (403 aa)
CSKR_13842sObg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (555 aa)
Guk1Guanylate kinase. (256 aa)
CSKR_3180sUncharacterized protein. (371 aa)
dom-2Helicase domino. (3123 aa)
HGPRT-2Hypoxanthine-guanine phosphoribosyltransferase. (249 aa)
Ak5Adenylate kinase isoenzyme 5. (757 aa)
Gyc32EGuanylate cyclase. (1825 aa)
ttll3Tubulin monoglycylase TTLL3. (1287 aa)
SVOPSynaptic vesicle 2-related protein. (451 aa)
gcy-28Receptor-type guanylate cyclase gcy-28. (854 aa)
Npr1Atrial natriuretic peptide receptor 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (306 aa)
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2. (377 aa)
CSKR_8834sUncharacterized protein. (303 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (549 aa)
AK8Adenylate kinase 8; Belongs to the adenylate kinase family. (484 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (1428 aa)
ADALAdenosine deaminase-like protein. (312 aa)
nme6Nucleoside diphosphate kinase 6; Belongs to the NDK family. (203 aa)
punAPurine nucleoside phosphorylase 1. (211 aa)
FBXL2F-box/LRR-repeat protein 2. (569 aa)
NME5Nucleoside diphosphate kinase-like protein 5; Belongs to the NDK family. (379 aa)
Pde1cPhosphodiesterase. (603 aa)
SVOP-2Synaptic vesicle 2-related protein. (418 aa)
Pde4bcAMP-specific 3. (224 aa)
PDE9APhosphodiesterase. (786 aa)
HGPRT-3Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (291 aa)
IPO13Importin-13. (1176 aa)
TTLL1Putative tubulin polyglutamylase TTLL1. (507 aa)
Cnnm2-2Metal transporter CNNM2. (622 aa)
PRUNEProtein prune-like protein. (785 aa)
CSKR_1558sUncharacterized protein. (159 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase 2. (344 aa)
Gyc88E-4Soluble guanylate cyclase 88E. (508 aa)
adkAdenylate kinase. (370 aa)
Ttll10Protein polyglycylase TTLL10. (767 aa)
NT5C3A-2Cytosolic 5'-nucleotidase 3A. (292 aa)
Nt5c2Cytosolic purine 5'-nucleotidase. (792 aa)
CaskPeripheral plasma membrane protein CASK. (401 aa)
Ampd2-3AMP deaminase 2. (232 aa)
Mpp7MAGUK p55 subfamily member 7; Belongs to the MAGUK family. (600 aa)
dlg1-3Disks large-like protein 1. (311 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (619 aa)
NPR1Guanylate cyclase. (583 aa)
Pde9a-2High affinity cGMP-specific 3; Belongs to the cyclic nucleotide phosphodiesterase family. (385 aa)
HellsLymphocyte-specific helicase. (1556 aa)
Guk1-2Guanylate kinase. (200 aa)
CSKR_6392sPDZ domain-containing protein. (498 aa)
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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