(152 nodes) Exocytosis, and Dopamine Neurotransmitter Release Cycle network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	syt1	Synaptotagmin Ia. (418 aa)
	W5JYK0_ASTMX	RIMS binding protein 2. (1040 aa)
	mpp6	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (549 aa)
	W5JZI3_ASTMX	C2 domain-containing protein. (267 aa)
	stxbp3	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (591 aa)
	LOC103031680	Synapsin I. (632 aa)
	LOC103028624	Membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4); Belongs to the MAGUK family. (622 aa)
	Tspo	Translocator protein. (170 aa)
	W5K587_ASTMX	Uncharacterized protein. (956 aa)
	Ppfia3	Uncharacterized protein. (232 aa)
	LOC103046737	Synaptotagmin-like 2b. (1815 aa)
	W5K6K5_ASTMX	Phosphatase and actin regulator 3b. (414 aa)
	W5K6R5_ASTMX	PPFIA binding protein 2a. (279 aa)
	syt7	Synaptotagmin VIIb. (655 aa)
	W5K7E2_ASTMX	Pleckstrin homology-like domain, family B, member 1a. (1456 aa)
	W5K9J0_ASTMX	Synaptotagmin Ib. (419 aa)
	W5KA92_ASTMX	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1806 aa)
	W5KAI8_ASTMX	Solute carrier family 17 member 5. (448 aa)
	W5KCW8_ASTMX	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (786 aa)
	LOC103038197	RAB3D, member RAS oncogene family, b. (233 aa)
	Ppfia2	PTPRF interacting protein alpha 2. (1137 aa)
	Lin7c	Lin-7 homolog C (C. elegans). (248 aa)
	W5KFS7_ASTMX	MAP-kinase activating death domain. (1531 aa)
	Apba1	Amyloid beta (A4) precursor protein-binding, family A, member 1a. (885 aa)
	LOC103045701	Aa_trans domain-containing protein. (468 aa)
	mlph	Melanophilin a. (580 aa)
	W5KQZ9_ASTMX	Protein tyrosine phosphatase receptor type T. (1369 aa)
	snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (204 aa)
	W5KSW2_ASTMX	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (193 aa)
	LOC107196972	Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (547 aa)
	stxbp1	Syntaxin binding protein 1a; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
	LOC103042251	Synaptotagmin IIa. (431 aa)
	W5KUX5_ASTMX	Lin-7 homolog B (C. elegans). (207 aa)
	sytl2	Uncharacterized protein. (943 aa)
	rims1	Regulating synaptic membrane exocytosis 1a. (1587 aa)
	LOC103028270	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (561 aa)
	syt9	Synaptotagmin IXb. (518 aa)
	W5L1R1_ASTMX	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (854 aa)
	LOC103047010	Synaptotagmin VIb. (541 aa)
	LOC103044978	Syntaxin binding protein 5a (tomosyn). (1122 aa)
	W5L849_ASTMX	Retinol saturase (all-trans-retinol 13,14-reductase) like. (560 aa)
	W5L8D5_ASTMX	Syntaxin binding protein 1b; Belongs to the STXBP/unc-18/SEC1 family. (544 aa)
	LOC103032219	Solute carrier family 18 member 2. (512 aa)
	LOC103039832	Amyloid beta precursor protein binding family A member 3. (711 aa)
	LOC103026901	RAB3A, member RAS oncogene family, a. (227 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1264 aa)
	LOC103035847	Uncharacterized protein. (426 aa)
	stxbp2	Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	LOC103024303	Taxilin gamma. (457 aa)
	UNC13C	Unc-13 homolog C. (2005 aa)
	snap47	Synaptosome associated protein 47. (431 aa)
	SLC18A1	Solute carrier family 18 member A1. (518 aa)
	RAB3C	RAB3C, member RAS oncogene family. (215 aa)
	HECTD4	HECT domain E3 ubiquitin protein ligase 4. (4273 aa)
	kiaa0319l	Si:ch211-193k19.1. (982 aa)
	LOC103042153	Si:ch1073-513e17.1. (506 aa)
	stx11	Syntaxin 11a; Belongs to the syntaxin family. (294 aa)
	W5LT97_ASTMX	Solute carrier family 18 member 3b. (490 aa)
	W5LU88_ASTMX	C2 domain-containing protein. (137 aa)
	LOC103029345	C2 domain-containing protein. (387 aa)
	stx1a	Syntaxin 1A (brain); Belongs to the syntaxin family. (324 aa)
	LOC103027359	RAB3B, member RAS oncogene family. (217 aa)
	ENSAMXP00000028619	Uncharacterized protein. (1911 aa)
	LOC103036084	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (201 aa)
	gmip	GEM interacting protein. (994 aa)
	Cask	Calcium/calmodulin-dependent serine protein kinase a; Belongs to the MAGUK family. (886 aa)
	ENSAMXP00000031958	Synaptotagmin VIIa. (791 aa)
	ppfia4	PTPRF interacting protein alpha 4. (1195 aa)
	LOC103029374	Synaptotagmin-like 1. (536 aa)
	SYN3	Synapsin III. (530 aa)
	sytl4	Synaptotagmin-like 4. (727 aa)
	LOC103044545	RabBD domain-containing protein. (591 aa)
	ENSAMXP00000034301	Uncharacterized protein. (184 aa)
	ENSAMXP00000034378	Zgc:92912. (124 aa)
	LOC103031721	Synapsin IIb. (732 aa)
	ENSAMXP00000034544	C2 domain-containing protein. (277 aa)
	ENSAMXP00000034546	Uncharacterized protein. (299 aa)
	vamp2	Vesicle-associated membrane protein 2. (120 aa)
	vamp3	Vesicle-associated membrane protein 3 (cellubrevin). (102 aa)
	ENSAMXP00000034950	Uncharacterized protein. (459 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (321 aa)
	ENSAMXP00000035150	Unc-13 homolog Ba (C. elegans). (1152 aa)
	rims4	Regulating synaptic membrane exocytosis 4. (269 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (290 aa)
	ENSAMXP00000036297	Uncharacterized protein. (404 aa)
	LOC103029888	Synaptotagmin Vb. (443 aa)
	txlna	Taxilin alpha. (533 aa)
	LOC103021300	Synaptotagmin XIb. (465 aa)
	ENSAMXP00000038348	Uncharacterized protein. (297 aa)
	ENSAMXP00000038550	C2 domain-containing protein. (131 aa)
	RIMS2-2	Regulating synaptic membrane exocytosis 2. (1414 aa)
	Rab3c	RAB3C, member RAS oncogene family. (217 aa)
	ENSAMXP00000039084	Uncharacterized protein. (291 aa)
	ENSAMXP00000039525	MAM domain-containing protein. (66 aa)
	ENSAMXP00000039622	Uncharacterized protein. (110 aa)
	ENSAMXP00000040379	Synaptotagmin XVI. (537 aa)
	syt4	Synaptotagmin IV. (444 aa)
	rab3a	RAB3A, member RAS oncogene family, b. (220 aa)
	ENSAMXP00000040902	RabBD domain-containing protein. (286 aa)
	ENSAMXP00000041201	Uncharacterized protein. (74 aa)
	LOC107197223	C2 domain-containing protein. (3580 aa)
	LOC103040229	Protein tyrosine phosphatase receptor type Ub. (1415 aa)
	ENSAMXP00000042526	Uncharacterized protein. (236 aa)
	ENSAMXP00000042620	Uncharacterized protein. (104 aa)
	ENSAMXP00000042722	Uncharacterized protein; Belongs to the MAGUK family. (540 aa)
	LOC103027827	Synaptotagmin Va. (409 aa)
	LOC103042206	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1055 aa)
	ENSAMXP00000043594	Uncharacterized protein. (264 aa)
	LOC103033225	Synaptotagmin XIa. (449 aa)
	Mpp1	Membrane protein, palmitoylated 1; Belongs to the MAGUK family. (551 aa)
	Edrf1	Uncharacterized protein. (330 aa)
	LOC103045253	PPFIA binding protein 1b. (1013 aa)
	ENSAMXP00000044323	Si:ch211-240l19.5. (134 aa)
	LOC103031140	Unc-13 homolog A. (1891 aa)
	sytl5	Synaptotagmin-like 5. (693 aa)
	ENSAMXP00000045000	Rabphilin 3A homolog (mouse), b. (539 aa)
	ENSAMXP00000045306	C2 domain-containing protein. (146 aa)
	rab27b	RAB27B, member RAS oncogene family. (217 aa)
	Tspoap1	Uncharacterized protein. (1521 aa)
	Tmx3	Thioredoxin domain-containing protein. (79 aa)
	LOC103022099	PPFIA binding protein 1a. (910 aa)
	ENSAMXP00000046843	Uncharacterized protein. (683 aa)
	slc17a6	Solute carrier family 17 member 6a. (589 aa)
	ENSAMXP00000047589	Uncharacterized protein. (71 aa)
	syt12	Synaptotagmin XII. (420 aa)
	LOC103044022	Synaptotagmin XIVa. (607 aa)
	LOC103023237	Syntaxin 2b; Belongs to the syntaxin family. (317 aa)
	LOC103046345	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (268 aa)
	LOC103026481	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	LOC103042529	Syntaxin 1B; Belongs to the syntaxin family. (288 aa)
	ENSAMXP00000048553	Synaptotagmin IXa. (499 aa)
	ENSAMXP00000049215	Uncharacterized protein. (157 aa)
	mpp4	Membrane protein, palmitoylated 4-like; Belongs to the MAGUK family. (627 aa)
	LOC103032718	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (203 aa)
	LOC103024379	Solute carrier family 17 member 7a. (582 aa)
	LOC103021971	Syntaxin binding protein 5b (tomosyn). (1210 aa)
	Lin7a	Lin-7 homolog A (C. elegans). (232 aa)
	ENSAMXP00000050742	Uncharacterized protein. (67 aa)
	ENSAMXP00000050763	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (292 aa)
	ENSAMXP00000050820	Uncharacterized protein. (360 aa)
	scgn	Secretagogin, EF-hand calcium binding protein. (272 aa)
	rab27a	RAB27A, member RAS oncogene family. (222 aa)
	ENSAMXP00000051785	Phosphatase and actin regulator. (494 aa)
	ppfia1	PTPRF interacting protein alpha 1. (1254 aa)
	c2h16orf89	Si:ch211-76l23.7. (378 aa)
	LOC103041393	Synaptotagmin VIa. (542 aa)
	ENSAMXP00000052960	Phosphatase and actin regulator. (142 aa)
	LOC103025380	Complexin 2. (134 aa)
	ENSAMXP00000053563	Uncharacterized protein. (1615 aa)
	LOC103030083	Vesicle-associated membrane protein 1. (120 aa)
	LOC103028541	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (939 aa)
	LOC103039585	LHFPL tetraspan subfamily member 2b. (221 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apba1	Cask	ENSAMXP00000008807	ENSAMXP00000029864	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Calcium/calmodulin-dependent serine protein kinase a; Belongs to the MAGUK family.	0.951
Apba1	ENSAMXP00000034378	ENSAMXP00000008807	ENSAMXP00000034378	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Zgc:92912.	0.417
Apba1	ENSAMXP00000034950	ENSAMXP00000008807	ENSAMXP00000034950	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein.	0.455
Apba1	ENSAMXP00000042620	ENSAMXP00000008807	ENSAMXP00000042620	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein.	0.581
Apba1	ENSAMXP00000042722	ENSAMXP00000008807	ENSAMXP00000042722	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein; Belongs to the MAGUK family.	0.656
Apba1	ENSAMXP00000043594	ENSAMXP00000008807	ENSAMXP00000043594	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein.	0.455
Apba1	ENSAMXP00000050763	ENSAMXP00000008807	ENSAMXP00000050763	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.567
Apba1	ENSAMXP00000053563	ENSAMXP00000008807	ENSAMXP00000053563	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein.	0.427
Apba1	LOC103023237	ENSAMXP00000008807	ENSAMXP00000047841	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Syntaxin 2b; Belongs to the syntaxin family.	0.567
Apba1	LOC103025380	ENSAMXP00000008807	ENSAMXP00000053326	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Complexin 2.	0.416
Apba1	LOC103026481	ENSAMXP00000008807	ENSAMXP00000048210	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Syntaxin 4; Belongs to the syntaxin family.	0.536
Apba1	LOC103028270	ENSAMXP00000008807	ENSAMXP00000012458	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.656
Apba1	LOC103028624	ENSAMXP00000008807	ENSAMXP00000002248	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4); Belongs to the MAGUK family.	0.494
Apba1	LOC103030083	ENSAMXP00000008807	ENSAMXP00000053746	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Vesicle-associated membrane protein 1.	0.417
Apba1	LOC103032718	ENSAMXP00000008807	ENSAMXP00000049627	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.510
Apba1	LOC103042529	ENSAMXP00000008807	ENSAMXP00000048367	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Syntaxin 1B; Belongs to the syntaxin family.	0.567
Apba1	LOC107196972	ENSAMXP00000008807	ENSAMXP00000010835	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.656
Apba1	Lin7a	ENSAMXP00000008807	ENSAMXP00000050493	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Lin-7 homolog A (C. elegans).	0.581
Apba1	Lin7c	ENSAMXP00000008807	ENSAMXP00000006225	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Lin-7 homolog C (C. elegans).	0.581
Apba1	Mpp1	ENSAMXP00000008807	ENSAMXP00000043909	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Membrane protein, palmitoylated 1; Belongs to the MAGUK family.	0.784