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W5JYR7_ASTMX W5JYR7_ASTMX LOC103034175 LOC103034175 Gdf3 Gdf3 LOC103021856 LOC103021856 tgfb1 tgfb1 smad6 smad6 LOC103026097 LOC103026097 LOC103027845 LOC103027845 W5KF46_ASTMX W5KF46_ASTMX W5KFJ0_ASTMX W5KFJ0_ASTMX LOC103040899 LOC103040899 LOC103024607 LOC103024607 gdf5 gdf5 ACVR1 ACVR1 smad5 smad5 chrd chrd Gdf7 Gdf7 LOC103046211 LOC103046211 tgfb3 tgfb3 SMURF2 SMURF2 nodal nodal LOC103027116 LOC103027116 W5LD66_ASTMX W5LD66_ASTMX LOC103022359 LOC103022359 W5LH80_ASTMX W5LH80_ASTMX mstn mstn LOC103029394 LOC103029394 W5LJ85_ASTMX W5LJ85_ASTMX W5LJD2_ASTMX W5LJD2_ASTMX tgfbr2 tgfbr2 LOC103023108 LOC103023108 acvr2b acvr2b LOC103026512 LOC103026512 Grem2 Grem2 LOC103029721 LOC103029721 NBL1 NBL1 LOC103035375 LOC103035375 ENSAMXP00000028486 ENSAMXP00000028486 LOC103032572 LOC103032572 LOC103042113 LOC103042113 LOC103038302 LOC103038302 Bmpr2 Bmpr2 bmp6 bmp6 LOC103031474 LOC103031474 bmp5 bmp5 bmpr1b bmpr1b LOC103027004 LOC103027004 LOC103035751 LOC103035751 LOC103035022 LOC103035022 LOC103031084 LOC103031084 ENSAMXP00000033251 ENSAMXP00000033251 ENSAMXP00000033639 ENSAMXP00000033639 INHBC INHBC smad2 smad2 LOC103028976 LOC103028976 ENSAMXP00000035854 ENSAMXP00000035854 LOC103029324 LOC103029324 LOC103030936 LOC103030936 LOC103025287 LOC103025287 LOC103044553 LOC103044553 smad1 smad1 ENSAMXP00000040747 ENSAMXP00000040747 LOC103040263 LOC103040263 smurf1 smurf1 gdf11 gdf11 LOC103033691 LOC103033691 LOC103042559 LOC103042559 INHBB INHBB LOC103025122 LOC103025122 bmp4 bmp4 LOC103041954 LOC103041954 LOC103027811 LOC103027811 skil skil ENSAMXP00000047553 ENSAMXP00000047553 LOC103035745 LOC103035745 LOC103041475 LOC103041475 ENSAMXP00000050348 ENSAMXP00000050348 LOC103025967 LOC103025967 ENSAMXP00000050414 ENSAMXP00000050414 bmp10 bmp10 fst fst ENSAMXP00000050762 ENSAMXP00000050762 smad7 smad7 ACVR1C ACVR1C ENSAMXP00000053345 ENSAMXP00000053345 Bmp7 Bmp7 fstl3 fstl3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5JYR7_ASTMXLeft-right determination factor. (381 aa)
LOC103034175Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
Gdf3Growth differentiation factor 3. (360 aa)
LOC103021856Bone morphogenetic protein 2a. (405 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
smad6Mothers against decapentaplegic homolog. (480 aa)
LOC103026097Inhibin subunit beta B. (387 aa)
LOC103027845SKI-like proto-oncogene b. (715 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
W5KFJ0_ASTMXMothers against decapentaplegic homolog. (468 aa)
LOC103040899Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
gdf5Growth differentiation factor 5. (431 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (679 aa)
smad5Mothers against decapentaplegic homolog. (464 aa)
chrdChordin; Belongs to the chordin family. (945 aa)
Gdf7Growth differentiation factor 7. (429 aa)
LOC103046211V-ski avian sarcoma viral oncogene homolog a. (790 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
SMURF2E3 ubiquitin-protein ligase. (761 aa)
nodalNodal-related 2. (373 aa)
LOC103027116Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
W5LH80_ASTMXZinc finger, FYVE domain containing 9b. (760 aa)
mstnMyostatin b. (435 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
W5LJ85_ASTMXZinc finger, FYVE domain containing 9a. (1227 aa)
W5LJD2_ASTMXReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LOC103023108Southpaw. (418 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC103026512Gremlin 2, DAN family BMP antagonist a. (195 aa)
Grem2Gremlin 2, DAN family BMP antagonist b. (166 aa)
LOC103029721BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (276 aa)
NBL1NBL1, DAN family BMP antagonist. (271 aa)
LOC103035375Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (519 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
LOC103032572Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
LOC103042113Bone morphogenetic protein 7a. (403 aa)
LOC103038302Inhibin subunit beta Ab. (431 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
bmp6Bone morphogenetic protein 6. (427 aa)
LOC103031474V-ski avian sarcoma viral oncogene homolog b. (964 aa)
bmp5Bone morphogenetic protein 5. (445 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
LOC103035751Follistatin b. (362 aa)
LOC103035022Growth differentiation factor 6a. (406 aa)
LOC103031084Bone morphogenetic protein 10, like. (462 aa)
ENSAMXP00000033251Bone morphogenetic protein 8a. (450 aa)
ENSAMXP00000033639Mothers against decapentaplegic homolog. (425 aa)
INHBCInhibin subunit beta C. (389 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
LOC103028976Bone morphogenetic protein 2b. (445 aa)
ENSAMXP00000035854Noggin; Belongs to the noggin family. (209 aa)
LOC103029324Bone morphogenetic protein 16. (430 aa)
LOC103030936BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (265 aa)
LOC103025287Myostatin a. (348 aa)
LOC103044553Gremlin 1a, DAN family BMP antagonist. (171 aa)
smad1Mothers against decapentaplegic homolog. (488 aa)
ENSAMXP00000040747Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (578 aa)
LOC103040263Growth differentiation factor 2. (404 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
gdf11Growth differentiation factor 11. (409 aa)
LOC103033691Inhibin subunit beta Aa. (392 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
INHBBInhibin subunit beta B. (389 aa)
LOC103025122Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
bmp4TGF_BETA_2 domain-containing protein. (481 aa)
LOC103041954Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
skilSKI-like proto-oncogene a. (681 aa)
ENSAMXP00000047553Nodal-related 1. (115 aa)
LOC103035745Growth differentiation factor 6b. (398 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ENSAMXP00000050348Zinc finger, FYVE domain containing 16. (1404 aa)
LOC103025967Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
ENSAMXP00000050414E3 ubiquitin-protein ligase. (752 aa)
bmp10Bone morphogenetic protein 10. (492 aa)
fstFollistatin a. (347 aa)
ENSAMXP00000050762Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (495 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
Bmp7Bone morphogenetic protein 7b. (416 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (244 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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