STRINGSTRING
LOC103034175 LOC103034175 tgfb1 tgfb1 smad6 smad6 LOC103027845 LOC103027845 W5KF46_ASTMX W5KF46_ASTMX W5KFJ0_ASTMX W5KFJ0_ASTMX LOC103024607 LOC103024607 LOC103046211 LOC103046211 tgfb3 tgfb3 SMURF2 SMURF2 W5LD66_ASTMX W5LD66_ASTMX LOC103022359 LOC103022359 LOC103029394 LOC103029394 W5LJ85_ASTMX W5LJ85_ASTMX tgfbr2 tgfbr2 ENSAMXP00000028486 ENSAMXP00000028486 LOC103031474 LOC103031474 LOC103027004 LOC103027004 ENSAMXP00000033639 ENSAMXP00000033639 smad2 smad2 smurf1 smurf1 LOC103042559 LOC103042559 LOC103027811 LOC103027811 skil skil ENSAMXP00000050348 ENSAMXP00000050348 ENSAMXP00000050414 ENSAMXP00000050414 ENSAMXP00000050762 ENSAMXP00000050762 smad7 smad7 ENSAMXP00000053345 ENSAMXP00000053345
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103034175Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
smad6Mothers against decapentaplegic homolog. (480 aa)
LOC103027845SKI-like proto-oncogene b. (715 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
W5KFJ0_ASTMXMothers against decapentaplegic homolog. (468 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
LOC103046211V-ski avian sarcoma viral oncogene homolog a. (790 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
SMURF2E3 ubiquitin-protein ligase. (761 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
W5LJ85_ASTMXZinc finger, FYVE domain containing 9a. (1227 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
LOC103031474V-ski avian sarcoma viral oncogene homolog b. (964 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
ENSAMXP00000033639Mothers against decapentaplegic homolog. (425 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
skilSKI-like proto-oncogene a. (681 aa)
ENSAMXP00000050348Zinc finger, FYVE domain containing 16. (1404 aa)
ENSAMXP00000050414E3 ubiquitin-protein ligase. (752 aa)
ENSAMXP00000050762Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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