(12 nodes) Extrinsic Pathway of Fibrin Clot Formation, and Coagulation factor 5/8-like network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103033862	Coagulation factor IXa. (510 aa)
	f3	Coagulation factor IIIa. (290 aa)
	F3	Coagulation factor III, tissue factor. (293 aa)
	W5K8Z0_ASTMX	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family. (1720 aa)
	LOC103025270	Tissue factor pathway inhibitor. (270 aa)
	f9	Coagulation factor IXb. (494 aa)
	proc	Uncharacterized protein; Belongs to the peptidase S1 family. (443 aa)
	LOC103041525	Uncharacterized protein. (486 aa)
	LOC103046381	Coagulation factor VII. (442 aa)
	LOC103042318	Si:ch1073-416d2.3; Belongs to the serpin family. (403 aa)
	thbd	Thrombomodulin. (536 aa)
	ENSAMXP00000051116	Coagulation factor VIIi. (463 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000051116	F3	ENSAMXP00000051116	ENSAMXP00000000772	Coagulation factor VIIi.	Coagulation factor III, tissue factor.	0.674
ENSAMXP00000051116	LOC103025270	ENSAMXP00000051116	ENSAMXP00000015806	Coagulation factor VIIi.	Tissue factor pathway inhibitor.	0.593
ENSAMXP00000051116	LOC103033862	ENSAMXP00000051116	ENSAMXP00000000045	Coagulation factor VIIi.	Coagulation factor IXa.	0.423
ENSAMXP00000051116	LOC103042318	ENSAMXP00000051116	ENSAMXP00000048152	Coagulation factor VIIi.	Si:ch1073-416d2.3; Belongs to the serpin family.	0.602
ENSAMXP00000051116	LOC103046381	ENSAMXP00000051116	ENSAMXP00000046443	Coagulation factor VIIi.	Coagulation factor VII.	0.410
ENSAMXP00000051116	W5K8Z0_ASTMX	ENSAMXP00000051116	ENSAMXP00000004051	Coagulation factor VIIi.	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	0.623
ENSAMXP00000051116	f3	ENSAMXP00000051116	ENSAMXP00000000119	Coagulation factor VIIi.	Coagulation factor IIIa.	0.674
ENSAMXP00000051116	f9	ENSAMXP00000051116	ENSAMXP00000034646	Coagulation factor VIIi.	Coagulation factor IXb.	0.434
ENSAMXP00000051116	proc	ENSAMXP00000051116	ENSAMXP00000041155	Coagulation factor VIIi.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.559
ENSAMXP00000051116	thbd	ENSAMXP00000051116	ENSAMXP00000048988	Coagulation factor VIIi.	Thrombomodulin.	0.437
F3	ENSAMXP00000051116	ENSAMXP00000000772	ENSAMXP00000051116	Coagulation factor III, tissue factor.	Coagulation factor VIIi.	0.674
F3	LOC103025270	ENSAMXP00000000772	ENSAMXP00000015806	Coagulation factor III, tissue factor.	Tissue factor pathway inhibitor.	0.698
F3	LOC103033862	ENSAMXP00000000772	ENSAMXP00000000045	Coagulation factor III, tissue factor.	Coagulation factor IXa.	0.677
F3	LOC103041525	ENSAMXP00000000772	ENSAMXP00000043155	Coagulation factor III, tissue factor.	Uncharacterized protein.	0.674
F3	LOC103046381	ENSAMXP00000000772	ENSAMXP00000046443	Coagulation factor III, tissue factor.	Coagulation factor VII.	0.823
F3	f9	ENSAMXP00000000772	ENSAMXP00000034646	Coagulation factor III, tissue factor.	Coagulation factor IXb.	0.684
F3	proc	ENSAMXP00000000772	ENSAMXP00000041155	Coagulation factor III, tissue factor.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.524
F3	thbd	ENSAMXP00000000772	ENSAMXP00000048988	Coagulation factor III, tissue factor.	Thrombomodulin.	0.522
LOC103025270	ENSAMXP00000051116	ENSAMXP00000015806	ENSAMXP00000051116	Tissue factor pathway inhibitor.	Coagulation factor VIIi.	0.593
LOC103025270	F3	ENSAMXP00000015806	ENSAMXP00000000772	Tissue factor pathway inhibitor.	Coagulation factor III, tissue factor.	0.698