24 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Atm	Non-specific serine/threonine protein kinase. (3056 aa)
	W5JZ29_ASTMX	S-phase cyclin A-associated protein in the ER. (1312 aa)
	W5K1S4_ASTMX	MutS homolog 4. (783 aa)
	Bax	BCL2 associated X, apoptosis regulator a. (190 aa)
	W5KDL0_ASTMX	Phospholipase A2. (748 aa)
	W5KMS1_ASTMX	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (287 aa)
	LOC103034242	Phospholipase A2. (756 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (264 aa)
	LOC103023164	Bone morphogenetic protein 15. (397 aa)
	ube3a	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (873 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	Eif2b4	Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (516 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	LOC103041992	Pentraxin 3, long b. (409 aa)
	ZNF830	Zinc finger protein 830. (379 aa)
	gas2	Growth arrest-specific 2a. (319 aa)
	ptx3	Pentraxin 3, long a. (452 aa)
	spo11	SPO11 initiator of meiotic double stranded breaks. (383 aa)
	GPR149	G protein-coupled receptor 149. (748 aa)
	Amh	Anti-Mullerian hormone. (551 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	eif2b5	Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (731 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amh	LOC103023164	ENSAMXP00000046378	ENSAMXP00000011645	Anti-Mullerian hormone.	Bone morphogenetic protein 15.	0.698
Atm	W5K1S4_ASTMX	ENSAMXP00000044423	ENSAMXP00000001534	Non-specific serine/threonine protein kinase.	MutS homolog 4.	0.721
Atm	W5KMS1_ASTMX	ENSAMXP00000044423	ENSAMXP00000008883	Non-specific serine/threonine protein kinase.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.778
Atm	spo11	ENSAMXP00000044423	ENSAMXP00000045391	Non-specific serine/threonine protein kinase.	SPO11 initiator of meiotic double stranded breaks.	0.795
Eif2b4	eif2b5	ENSAMXP00000019859	ENSAMXP00000054221	Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family.	Eukaryotic translation initiation factor 2B, subunit 5 epsilon.	0.999
LOC103022359	LOC103029394	ENSAMXP00000018891	ENSAMXP00000019787	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103022359	W5LD66_ASTMX	ENSAMXP00000018891	ENSAMXP00000017778	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103023164	Amh	ENSAMXP00000011645	ENSAMXP00000046378	Bone morphogenetic protein 15.	Anti-Mullerian hormone.	0.698
LOC103029394	LOC103022359	ENSAMXP00000019787	ENSAMXP00000018891	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103029394	W5LD66_ASTMX	ENSAMXP00000019787	ENSAMXP00000017778	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103034242	W5KDL0_ASTMX	ENSAMXP00000010514	ENSAMXP00000005671	Phospholipase A2.	Phospholipase A2.	0.434
LOC103041992	tnfaip6	ENSAMXP00000034242	ENSAMXP00000011191	Pentraxin 3, long b.	Tumor necrosis factor, alpha-induced protein 6.	0.798
W5K1S4_ASTMX	Atm	ENSAMXP00000001534	ENSAMXP00000044423	MutS homolog 4.	Non-specific serine/threonine protein kinase.	0.721
W5K1S4_ASTMX	W5KMS1_ASTMX	ENSAMXP00000001534	ENSAMXP00000008883	MutS homolog 4.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.722
W5K1S4_ASTMX	spo11	ENSAMXP00000001534	ENSAMXP00000045391	MutS homolog 4.	SPO11 initiator of meiotic double stranded breaks.	0.722
W5KDL0_ASTMX	LOC103034242	ENSAMXP00000005671	ENSAMXP00000010514	Phospholipase A2.	Phospholipase A2.	0.434
W5KMS1_ASTMX	Atm	ENSAMXP00000008883	ENSAMXP00000044423	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	Non-specific serine/threonine protein kinase.	0.778
W5KMS1_ASTMX	W5K1S4_ASTMX	ENSAMXP00000008883	ENSAMXP00000001534	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	MutS homolog 4.	0.722
W5KMS1_ASTMX	spo11	ENSAMXP00000008883	ENSAMXP00000045391	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	SPO11 initiator of meiotic double stranded breaks.	0.894
W5LD66_ASTMX	LOC103022359	ENSAMXP00000017778	ENSAMXP00000018891	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901