20 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000047894	Endothelin 1. (162 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (780 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	Nfatc4	Nuclear factor of activated T cells 4. (812 aa)
	Gbx2	Gastrulation brain homeobox 2. (336 aa)
	LOC103024223	Secreted frizzled-related protein 2 like. (312 aa)
	sars1	Seryl-tRNA synthetase. (520 aa)
	tgfbr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
	nrarp	NOTCH regulated ankyrin repeat protein a. (112 aa)
	SRF	Serum response factor. (527 aa)
	hs6st2	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (475 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	NRARP	NOTCH regulated ankyrin repeat protein b. (107 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	LOC103035447	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (265 aa)
	LOC103042847	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa)
	LOC103042559	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	lef1	Lymphoid enhancer-binding factor 1. (384 aa)
	LOC103037384	Uncharacterized protein. (170 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.978
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.978
ENSAMXP00000047894	LOC107197257	ENSAMXP00000047894	ENSAMXP00000032052	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.971
LOC103024223	lef1	ENSAMXP00000011888	ENSAMXP00000044691	Secreted frizzled-related protein 2 like.	Lymphoid enhancer-binding factor 1.	0.565
LOC103037384	Nfatc4	ENSAMXP00000052062	ENSAMXP00000001822	Uncharacterized protein.	Nuclear factor of activated T cells 4.	0.786
LOC103042559	tgfbr2	ENSAMXP00000043824	ENSAMXP00000021003	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902
LOC103042847	Nfatc4	ENSAMXP00000041471	ENSAMXP00000001822	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.	Nuclear factor of activated T cells 4.	0.786
LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	ENSAMXP00000033131	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC107197257	ENSAMXP00000047894	ENSAMXP00000032052	ENSAMXP00000047894	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.971
Nfatc4	LOC103037384	ENSAMXP00000001822	ENSAMXP00000052062	Nuclear factor of activated T cells 4.	Uncharacterized protein.	0.786
Nfatc4	LOC103042847	ENSAMXP00000001822	ENSAMXP00000041471	Nuclear factor of activated T cells 4.	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.	0.786
lef1	LOC103024223	ENSAMXP00000044691	ENSAMXP00000011888	Lymphoid enhancer-binding factor 1.	Secreted frizzled-related protein 2 like.	0.565
tgfbr2	LOC103042559	ENSAMXP00000021003	ENSAMXP00000043824	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902