16 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	greb1	Growth regulating estrogen receptor binding 1. (1821 aa)
	LOC103031663	Transcription factor 21. (182 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	ilk	Integrin-linked kinase. (452 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	wt1	WT1 transcription factor a. (415 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	LOC103038135	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (169 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (245 aa)
	LOC103027348	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (146 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	tmem59l	Transmembrane protein 59-like. (339 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	ENSAMXP00000030591	WT1 transcription factor b. (391 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000030591	LOC103031663	ENSAMXP00000030591	ENSAMXP00000053939	WT1 transcription factor b.	Transcription factor 21.	0.479
LOC103022359	LOC103029394	ENSAMXP00000018891	ENSAMXP00000019787	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103022359	W5LD66_ASTMX	ENSAMXP00000018891	ENSAMXP00000017778	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103029394	LOC103022359	ENSAMXP00000019787	ENSAMXP00000018891	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103029394	W5LD66_ASTMX	ENSAMXP00000019787	ENSAMXP00000017778	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103031663	ENSAMXP00000030591	ENSAMXP00000053939	ENSAMXP00000030591	Transcription factor 21.	WT1 transcription factor b.	0.479
LOC103031663	wt1	ENSAMXP00000053939	ENSAMXP00000048185	Transcription factor 21.	WT1 transcription factor a.	0.595
W5LD66_ASTMX	LOC103022359	ENSAMXP00000017778	ENSAMXP00000018891	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
W5LD66_ASTMX	LOC103029394	ENSAMXP00000017778	ENSAMXP00000019787	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
wt1	LOC103031663	ENSAMXP00000048185	ENSAMXP00000053939	WT1 transcription factor a.	Transcription factor 21.	0.595