57 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tll1	Metalloendopeptidase. (1022 aa)
	W5JXX2_ASTMX	Uncharacterized protein. (125 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (157 aa)
	LOC103021856	Bone morphogenetic protein 2a. (405 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	LOC103032217	Dickkopf_N domain-containing protein. (277 aa)
	W5K4M9_ASTMX	Lysine (K)-specific demethylase 6A. (1252 aa)
	LOC103024888	Metalloendopeptidase. (976 aa)
	W5K922_ASTMX	T-box transcription factor Tb. (416 aa)
	LOC103033509	T-box transcription factor 19. (430 aa)
	W5KJA8_ASTMX	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa)
	LOC103024223	Secreted frizzled-related protein 2 like. (312 aa)
	W5L1S1_ASTMX	Lysine (K)-specific demethylase 6A, like. (1314 aa)
	LOC103038161	T-box transcription factor Ta. (422 aa)
	itgb4	Integrin beta. (1986 aa)
	Exoc4	Exocyst complex component 4. (961 aa)
	LOC103032002	Integrin, alpha 3a; Belongs to the integrin alpha chain family. (995 aa)
	nodal	Nodal-related 2. (373 aa)
	LOC103031298	Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
	LOC103045069	Metalloendopeptidase. (1044 aa)
	LOC103023108	Southpaw. (418 aa)
	msgn1	Mesogenin 1. (157 aa)
	LOC103043286	Forkhead box H1. (533 aa)
	SRF	Serum response factor. (527 aa)
	pofut2	Protein O-fucosyltransferase 2. (449 aa)
	LOC103046695	Neurofibromin 2b (merlin). (587 aa)
	LOC111193684	Si:ch211-161c3.6. (114 aa)
	sfrp5	Secreted frizzled-related protein 5. (313 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	ENSAMXP00000034556	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
	LOC103028976	Bone morphogenetic protein 2b. (445 aa)
	LOC103028490	Lysine (K)-specific demethylase 6B, b. (1798 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	armc5	Armadillo repeat containing 5. (1233 aa)
	ENSAMXP00000041224	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
	Lclat1	Lysocardiolipin acyltransferase 1. (364 aa)
	LOC103036102	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	lef1	Lymphoid enhancer-binding factor 1. (384 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (720 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	kdm6b	Lysine (K)-specific demethylase 6B, a. (1983 aa)
	efna5	Ephrin-A5b; Belongs to the ephrin family. (230 aa)
	taf10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (192 aa)
	ENSAMXP00000047553	Nodal-related 1. (115 aa)
	ENSAMXP00000049285	T-box transcription factor 16, like. (425 aa)
	LOC107197240	BHLH domain-containing protein. (244 aa)
	apela	Uncharacterized protein. (55 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	LOC103029061	Uncharacterized protein. (331 aa)
	nf2	Neurofibromin 2a (merlin). (591 aa)
	ENSAMXP00000050565	Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
	LOC103028810	Ephrin-A5a; Belongs to the ephrin family. (234 aa)
	ENSAMXP00000053702	Uncharacterized protein. (283 aa)
	Tal1	T-cell acute lymphocytic leukemia 1. (371 aa)
	LOC103040573	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1040 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmpr2	LOC103021856	ENSAMXP00000030317	ENSAMXP00000000963	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2a.	0.970
Bmpr2	LOC103028976	ENSAMXP00000030317	ENSAMXP00000035663	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2b.	0.970
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
ENSAMXP00000034556	ENSAMXP00000049285	ENSAMXP00000034556	ENSAMXP00000049285	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor 16, like.	0.565
ENSAMXP00000034556	LOC103024223	ENSAMXP00000034556	ENSAMXP00000011888	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2 like.	0.860
ENSAMXP00000034556	LOC103036102	ENSAMXP00000034556	ENSAMXP00000043261	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.473
ENSAMXP00000034556	LOC103038161	ENSAMXP00000034556	ENSAMXP00000014052	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Ta.	0.537
ENSAMXP00000034556	W5K922_ASTMX	ENSAMXP00000034556	ENSAMXP00000004083	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Tb.	0.555
ENSAMXP00000034556	W5KJA8_ASTMX	ENSAMXP00000034556	ENSAMXP00000007670	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.481
ENSAMXP00000034556	dkk1	ENSAMXP00000034556	ENSAMXP00000018708	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Dickkopf WNT signaling pathway inhibitor 1b.	0.596
ENSAMXP00000034556	lef1	ENSAMXP00000034556	ENSAMXP00000044691	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Lymphoid enhancer-binding factor 1.	0.617
ENSAMXP00000034556	sfrp5	ENSAMXP00000034556	ENSAMXP00000030242	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 5.	0.834
ENSAMXP00000041224	LOC103024223	ENSAMXP00000041224	ENSAMXP00000011888	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2 like.	0.616
ENSAMXP00000041224	LOC103036102	ENSAMXP00000041224	ENSAMXP00000043261	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.469
ENSAMXP00000041224	LOC103038161	ENSAMXP00000041224	ENSAMXP00000014052	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Ta.	0.513
ENSAMXP00000041224	W5K922_ASTMX	ENSAMXP00000041224	ENSAMXP00000004083	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Tb.	0.420
ENSAMXP00000041224	W5KJA8_ASTMX	ENSAMXP00000041224	ENSAMXP00000007670	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.469
ENSAMXP00000041224	dkk1	ENSAMXP00000041224	ENSAMXP00000018708	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Dickkopf WNT signaling pathway inhibitor 1b.	0.438
ENSAMXP00000041224	lef1	ENSAMXP00000041224	ENSAMXP00000044691	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Lymphoid enhancer-binding factor 1.	0.480
ENSAMXP00000041224	sfrp5	ENSAMXP00000041224	ENSAMXP00000030242	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 5.	0.547