86 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	efnb2	Ephrin-B2a; Belongs to the ephrin family. (342 aa)
	W5JXX2_ASTMX	Uncharacterized protein. (125 aa)
	crim1	Uncharacterized protein. (1024 aa)
	LOC103032217	Dickkopf_N domain-containing protein. (277 aa)
	W5K4M9_ASTMX	Lysine (K)-specific demethylase 6A. (1252 aa)
	pofut1	Protein O-fucosyltransferase 1. (396 aa)
	pdlim7	PDZ and LIM domain 7. (509 aa)
	axin1	Axin 1. (866 aa)
	chuk	Component of inhibitor of nuclear factor kappa B kinase complex. (755 aa)
	kif22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (637 aa)
	XRCC2	X-ray repair cross complementing 2. (305 aa)
	W5KJA8_ASTMX	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa)
	LOC103044365	E1A binding protein p300 a. (2671 aa)
	LOC103031030	Hairy-related 11. (286 aa)
	LOC103022868	RAP1A, member of RAS oncogene family b. (185 aa)
	W5KPS9_ASTMX	T-box transcription factor 6. (895 aa)
	naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit. (725 aa)
	LOC103024223	Secreted frizzled-related protein 2 like. (312 aa)
	chrd	Chordin; Belongs to the chordin family. (945 aa)
	LOC103044660	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (492 aa)
	LOC103030717	Uncharacterized protein. (750 aa)
	Prrc1	Proline-rich coiled-coil 1. (458 aa)
	W5L1S1_ASTMX	Lysine (K)-specific demethylase 6A, like. (1314 aa)
	ep300	E1A binding protein p300 b. (2652 aa)
	LOC103038161	T-box transcription factor Ta. (422 aa)
	LOC103034623	Notch receptor 1a. (2450 aa)
	dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	ENSAMXP00000027280	Abl-interactor 1a. (461 aa)
	ENSAMXP00000027320	Uncharacterized protein. (805 aa)
	LOC103043286	Forkhead box H1. (533 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	LOC103028370	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ENSAMXP00000029283	DUF4174 domain-containing protein. (116 aa)
	nle1	Notchless homolog 1 (Drosophila). (476 aa)
	LOC103041353	Mesenchyme homeobox 2b. (300 aa)
	ENSAMXP00000030961	DUF4174 domain-containing protein. (1189 aa)
	ENSAMXP00000031097	Ephrin-B2b. (229 aa)
	XRCC2-2	X-ray repair cross complementing 2. (248 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	ENSAMXP00000032319	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (298 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	vangl2	Vang-like protein. (524 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (743 aa)
	poglut1	Protein O-glucosyltransferase 1. (396 aa)
	Mib1	Mindbomb E3 ubiquitin protein ligase 1. (1027 aa)
	ENSAMXP00000039525	MAM domain-containing protein. (66 aa)
	ENSAMXP00000039539	Hairy-related 1. (280 aa)
	LOC103043375	Titin-cap (telethonin). (179 aa)
	churc1	Churchill domain containing 1. (112 aa)
	LOC103043517	Abl-interactor 1b. (465 aa)
	LOC103040229	Protein tyrosine phosphatase receptor type Ub. (1415 aa)
	ENSAMXP00000042910	Uncharacterized protein. (248 aa)
	ENSAMXP00000042986	Eph receptor B4b. (931 aa)
	LOC103036102	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	rap1b	RAP1B, member of RAS oncogene family. (184 aa)
	Atm	Non-specific serine/threonine protein kinase. (3056 aa)
	lef1	Lymphoid enhancer-binding factor 1. (384 aa)
	ENSAMXP00000044743	G_PROTEIN_RECEP_F2_3 domain-containing protein. (88 aa)
	ENSAMXP00000045405	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (437 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (210 aa)
	Ripply1	Ripply transcriptional repressor 1. (176 aa)
	efna5	Ephrin-A5b; Belongs to the ephrin family. (230 aa)
	LOC103030680	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
	taf10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (192 aa)
	LOC111194998	Transmembrane p24 trafficking protein 2. (202 aa)
	ENSAMXP00000049034	RRM domain-containing protein. (82 aa)
	LOC107197240	BHLH domain-containing protein. (244 aa)
	naa50	N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
	supt6h	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1743 aa)
	ENSAMXP00000050439	Calcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family. (415 aa)
	ENSAMXP00000050565	Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
	Dll3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	LOC103025197	Notch receptor 1b. (2477 aa)
	LOC103028810	Ephrin-A5a; Belongs to the ephrin family. (234 aa)
	LOC103043594	Hairy-related 1. (307 aa)
	rbm24	RNA binding motif protein 24a. (250 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	rap1a	RAP1A, member of RAS oncogene family a. (195 aa)
	ENSAMXP00000054649	Signal peptide, CUB domain, EGF-like 2. (976 aa)
	meox2	Mesenchyme homeobox 2a. (291 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	LOC103044365	ENSAMXP00000044423	ENSAMXP00000007693	Non-specific serine/threonine protein kinase.	E1A binding protein p300 a.	0.446
Atm	XRCC2	ENSAMXP00000044423	ENSAMXP00000006707	Non-specific serine/threonine protein kinase.	X-ray repair cross complementing 2.	0.693
Atm	XRCC2-2	ENSAMXP00000044423	ENSAMXP00000031221	Non-specific serine/threonine protein kinase.	X-ray repair cross complementing 2.	0.693
Atm	chuk	ENSAMXP00000044423	ENSAMXP00000004889	Non-specific serine/threonine protein kinase.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.419
Atm	ep300	ENSAMXP00000044423	ENSAMXP00000014014	Non-specific serine/threonine protein kinase.	E1A binding protein p300 b.	0.446
CDH2	LOC103030680	ENSAMXP00000031306	ENSAMXP00000046775	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.901
Dll3	LOC103025197	ENSAMXP00000050702	ENSAMXP00000051793	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1b.	0.976
Dll3	LOC103034623	ENSAMXP00000050702	ENSAMXP00000015021	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1a.	0.976
Dll3	Mib1	ENSAMXP00000050702	ENSAMXP00000037923	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb E3 ubiquitin protein ligase 1.	0.588
Dll3	dll1	ENSAMXP00000050702	ENSAMXP00000015776	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.915
ENSAMXP00000027280	vangl2	ENSAMXP00000027280	ENSAMXP00000035179	Abl-interactor 1a.	Vang-like protein.	0.451
ENSAMXP00000028486	LOC103043286	ENSAMXP00000028486	ENSAMXP00000028165	Mothers against decapentaplegic homolog.	Forkhead box H1.	0.644
ENSAMXP00000028486	LOC103044365	ENSAMXP00000028486	ENSAMXP00000007693	Mothers against decapentaplegic homolog.	E1A binding protein p300 a.	0.567
ENSAMXP00000028486	ep300	ENSAMXP00000028486	ENSAMXP00000014014	Mothers against decapentaplegic homolog.	E1A binding protein p300 b.	0.567
ENSAMXP00000028486	lef1	ENSAMXP00000028486	ENSAMXP00000044691	Mothers against decapentaplegic homolog.	Lymphoid enhancer-binding factor 1.	0.470
ENSAMXP00000029283	ENSAMXP00000030961	ENSAMXP00000029283	ENSAMXP00000030961	DUF4174 domain-containing protein.	DUF4174 domain-containing protein.	0.603
ENSAMXP00000030961	ENSAMXP00000029283	ENSAMXP00000030961	ENSAMXP00000029283	DUF4174 domain-containing protein.	DUF4174 domain-containing protein.	0.603
ENSAMXP00000031097	ENSAMXP00000042986	ENSAMXP00000031097	ENSAMXP00000042986	Ephrin-B2b.	Eph receptor B4b.	0.573
ENSAMXP00000031097	LOC103028810	ENSAMXP00000031097	ENSAMXP00000052157	Ephrin-B2b.	Ephrin-A5a; Belongs to the ephrin family.	0.478
ENSAMXP00000031097	LOC103030680	ENSAMXP00000031097	ENSAMXP00000046775	Ephrin-B2b.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.421