(99 nodes) Neuron migration network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111193679	Uncharacterized protein. (210 aa)
	bbs1	Bardet-Biedl syndrome 1. (588 aa)
	gpm6a	Glycoprotein M6Aa. (281 aa)
	LOC103040710	Activator of transcription and developmental regulator AUTS2 b. (769 aa)
	bbs4	Bardet-Biedl syndrome 4. (604 aa)
	tubgcp2	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (883 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	ENSAMXP00000031283	Fork-head domain-containing protein. (312 aa)
	ENSAMXP00000031130	Uncharacterized protein. (112 aa)
	dab1	DAB adaptor protein 1a. (595 aa)
	Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1439 aa)
	ENSAMXP00000029520	Fork-head domain-containing protein. (286 aa)
	ENSAMXP00000029353	Scribble planar cell polarity protein. (1804 aa)
	SRF	Serum response factor. (527 aa)
	ENSAMXP00000028655	Uncharacterized protein. (438 aa)
	ASTN2	Astrotactin 2. (892 aa)
	ENSAMXP00000027932	Uncharacterized protein. (278 aa)
	ENSAMXP00000027688	Uncharacterized protein. (124 aa)
	LOC103039018	Cyclin-dependent kinase 5 activator. (311 aa)
	W5LU00_ASTMX	Forkhead box G1a. (337 aa)
	W5LTK0_ASTMX	Forkhead box G1b. (323 aa)
	Pomgnt2	Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-). (590 aa)
	W5LQK0_ASTMX	Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family. (1272 aa)
	ADGRL3	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1231 aa)
	kiaa0319l	Si:ch211-193k19.1. (982 aa)
	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2. (943 aa)
	Mdga2	MAM domain containing glycosylphosphatidylinositol anchor 2a. (944 aa)
	GPM6A	Glycoprotein M6A. (255 aa)
	W5LIV1_ASTMX	Neogenin 1b. (1382 aa)
	W5LFE6_ASTMX	Rap guanine nucleotide exchange factor (GEF) 6. (801 aa)
	cep85l	Centrosomal protein 85, like. (762 aa)
	W5L940_ASTMX	Doublecortin-like kinase 1a. (736 aa)
	LOC103032002	Integrin, alpha 3a; Belongs to the integrin alpha chain family. (995 aa)
	RELN	Reelin. (3447 aa)
	Dcc	DCC netrin 1 receptor. (1425 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	W5KXE3_ASTMX	Doublecortin-like kinase 1b. (716 aa)
	sh3rf1	SH3 domain containing ring finger 1. (884 aa)
	pex13	Peroxisomal biogenesis factor 13. (401 aa)
	cdk5r1	Cyclin-dependent kinase 5 activator. (304 aa)
	Cntn2	Contactin 2. (996 aa)
	LOC103040803	Cadherin EGF LAG seven-pass G-type receptor 1b; Belongs to the G-protein coupled receptor 2 family. (3031 aa)
	supt5h	Transcription elongation factor SPT5. (1082 aa)
	pcm1	Pericentriolar material 1. (2032 aa)
	W5KN59_ASTMX	FAT atypical cadherin 3b. (4028 aa)
	W5KN35_ASTMX	Cadherin, EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2674 aa)
	LOC103023032	Cyclin-dependent kinase-like 5. (1111 aa)
	LOC103031419	Neogenin 1a. (1407 aa)
	lrrc1	Leucine rich repeat containing 1. (662 aa)
	Bax	BCL2 associated X, apoptosis regulator a. (190 aa)
	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1. (937 aa)
	adgra3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1394 aa)
	Fat3	FAT atypical cadherin 3a. (4535 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	W5JZB9_ASTMX	Neuron navigator 1b. (1441 aa)
	LOC103040573	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1040 aa)
	ENSAMXP00000054660	BarH-like homeobox 1a. (215 aa)
	CRK	CRK proto-oncogene, adaptor protein. (315 aa)
	ENSAMXP00000054208	Uncharacterized protein. (740 aa)
	ENSAMXP00000053585	Uncharacterized protein. (641 aa)
	ENSAMXP00000053551	Uncharacterized protein. (825 aa)
	LOC103037830	GATA binding protein 2a. (469 aa)
	vangl2	Vang-like protein. (524 aa)
	ENSAMXP00000035360	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family. (3051 aa)
	ndnf	Neuron-derived neurotrophic factor. (577 aa)
	ENSAMXP00000036116	Uncharacterized protein. (229 aa)
	LOC111193902	Cholecystokinin b. (147 aa)
	ENSAMXP00000037535	SUEL-type lectin domain-containing protein. (124 aa)
	LOC103029482	Uncharacterized protein. (271 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	astn1	Astrotactin 1. (1315 aa)
	LOC103023003	AAA domain-containing protein. (1537 aa)
	gas6	Uncharacterized protein. (659 aa)
	ENSAMXP00000041272	Latrophilin domain-containing protein. (204 aa)
	dnaaf4	Dynein axonemal assembly factor 4. (416 aa)
	ENSAMXP00000042404	Cyclin-dependent kinase 5 activator. (319 aa)
	vax1	Ventral anterior homeobox 1. (325 aa)
	LOC103025442	LIM homeobox 1a. (405 aa)
	Crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (312 aa)
	LOC103037310	Homeobox domain-containing protein. (323 aa)
	LOC103047622	Neuropilin; Belongs to the neuropilin family. (920 aa)
	LOC103036464	Si:ch73-215d9.1. (1050 aa)
	ENSAMXP00000045148	Uncharacterized protein. (86 aa)
	barhl2	BarH-like homeobox 2. (365 aa)
	ENSAMXP00000046398	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (270 aa)
	ENSAMXP00000046402	Latrophilin domain-containing protein. (175 aa)
	LOC103030680	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
	Rest	RE1-silencing transcription factor. (1235 aa)
	pex7	Peroxisomal biogenesis factor 7. (319 aa)
	ENSAMXP00000048359	Si:dkey-253i9.4. (1139 aa)
	crk	V-crk avian sarcoma virus CT10 oncogene homolog. (307 aa)
	Celsr3	Cadherin, EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3076 aa)
	ENSAMXP00000050380	Uncharacterized protein. (250 aa)
	phox2b	Paired like homeobox 2Bb. (284 aa)
	alkbh1	AlkB homolog 1, histone H2A dioxygenase. (381 aa)
	ENSAMXP00000052303	Uncharacterized protein. (399 aa)
	ENSAMXP00000052447	Cholecystokinin a. (135 aa)
	dcx	Uncharacterized protein. (691 aa)
	ENSAMXP00000052670	Protein kinase domain-containing protein. (246 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL3	ENSAMXP00000029353	ENSAMXP00000021904	ENSAMXP00000029353	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Scribble planar cell polarity protein.	0.598
ADGRL3	ENSAMXP00000046398	ENSAMXP00000021904	ENSAMXP00000046398	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.894
ADGRL3	ENSAMXP00000046402	ENSAMXP00000021904	ENSAMXP00000046402	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Latrophilin domain-containing protein.	0.715
ADGRL3	adgra3	ENSAMXP00000021904	ENSAMXP00000002503	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	0.605
ADGRL3	lrrc1	ENSAMXP00000021904	ENSAMXP00000005404	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 1.	0.598
CDH2	LOC103030680	ENSAMXP00000031306	ENSAMXP00000046775	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.901
CRK	Crkl	ENSAMXP00000054310	ENSAMXP00000042943	CRK proto-oncogene, adaptor protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.913
CRK	ENSAMXP00000046398	ENSAMXP00000054310	ENSAMXP00000046398	CRK proto-oncogene, adaptor protein.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.450
CRK	LOC103032002	ENSAMXP00000054310	ENSAMXP00000015904	CRK proto-oncogene, adaptor protein.	Integrin, alpha 3a; Belongs to the integrin alpha chain family.	0.757
CRK	LOC103040573	ENSAMXP00000054310	ENSAMXP00000055079	CRK proto-oncogene, adaptor protein.	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	0.757
CRK	crk	ENSAMXP00000054310	ENSAMXP00000048997	CRK proto-oncogene, adaptor protein.	V-crk avian sarcoma virus CT10 oncogene homolog.	0.902
CRK	dab1	ENSAMXP00000054310	ENSAMXP00000031083	CRK proto-oncogene, adaptor protein.	DAB adaptor protein 1a.	0.485
Celsr3	W5KN35_ASTMX	ENSAMXP00000049533	ENSAMXP00000008997	Cadherin, EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	Cadherin, EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.402
Celsr3	vangl2	ENSAMXP00000049533	ENSAMXP00000035179	Cadherin, EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	Vang-like protein.	0.589
Crkl	CRK	ENSAMXP00000042943	ENSAMXP00000054310	V-crk avian sarcoma virus CT10 oncogene homolog-like.	CRK proto-oncogene, adaptor protein.	0.913
Crkl	ENSAMXP00000046398	ENSAMXP00000042943	ENSAMXP00000046398	V-crk avian sarcoma virus CT10 oncogene homolog-like.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.450
Crkl	LOC103032002	ENSAMXP00000042943	ENSAMXP00000015904	V-crk avian sarcoma virus CT10 oncogene homolog-like.	Integrin, alpha 3a; Belongs to the integrin alpha chain family.	0.757
Crkl	LOC103040573	ENSAMXP00000042943	ENSAMXP00000055079	V-crk avian sarcoma virus CT10 oncogene homolog-like.	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	0.757
Crkl	crk	ENSAMXP00000042943	ENSAMXP00000048997	V-crk avian sarcoma virus CT10 oncogene homolog-like.	V-crk avian sarcoma virus CT10 oncogene homolog.	0.913
Crkl	dab1	ENSAMXP00000042943	ENSAMXP00000031083	V-crk avian sarcoma virus CT10 oncogene homolog-like.	DAB adaptor protein 1a.	0.485