48 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccdc85b	Coiled-coil domain containing 85B. (200 aa)
	sall4	Spalt-like transcription factor 4. (1107 aa)
	abl2	Tyrosine-protein kinase. (1149 aa)
	W5K4M9_ASTMX	Lysine (K)-specific demethylase 6A. (1252 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	Cthrc1	Collagen triple helix repeat containing 1a. (268 aa)
	LOC103034112	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
	W5KIU0_ASTMX	MKS transition zone complex subunit 1. (528 aa)
	Hectd1	HECT domain containing 1. (2595 aa)
	W5KMM6_ASTMX	TSC complex subunit 1b. (1211 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	W5KTH2_ASTMX	TSC complex subunit 2. (1705 aa)
	LOC103024223	Secreted frizzled-related protein 2 like. (312 aa)
	fuz	Fuzzy planar cell polarity protein. (448 aa)
	mthfd1	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
	LOC103027200	Bromo domain-containing protein. (1529 aa)
	dvl2	Dishevelled segment polarity protein 2. (752 aa)
	LOC103035729	Dishevelled segment polarity protein 1a. (731 aa)
	W5L1S1_ASTMX	Lysine (K)-specific demethylase 6A, like. (1314 aa)
	W5L3R0_ASTMX	Dishevelled segment polarity protein 3b. (662 aa)
	mthfr	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (657 aa)
	tsc1	TSC complex subunit 1a. (1148 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (395 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2886 aa)
	bbs4	Bardet-Biedl syndrome 4. (604 aa)
	PHACTR1	Phosphatase and actin regulator. (603 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa)
	LOC103045871	Collagen triple helix repeat containing 1b. (257 aa)
	LOC103041872	Phosphatase and actin regulator. (919 aa)
	LOC103042896	Dishevelled segment polarity protein 3a. (676 aa)
	LOC103046091	Phosphatase and actin regulator 4a. (1040 aa)
	LOC103024868	Serine peptidase inhibitor, Kunitz type 1 b. (470 aa)
	ENSAMXP00000037031	MKS transition zone complex subunit 1. (534 aa)
	abl1	Tyrosine-protein kinase. (1107 aa)
	deaf1	DEAF1 transcription factor. (527 aa)
	ENSAMXP00000041303	Uncharacterized protein. (196 aa)
	ENSAMXP00000041588	Protein kinase domain-containing protein. (117 aa)
	LOC103047885	Serine peptidase inhibitor, Kunitz type, 2. (423 aa)
	LOC103024963	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (419 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (210 aa)
	LOC103023241	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
	LOC111194998	Transmembrane p24 trafficking protein 2. (202 aa)
	sdc4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (244 aa)
	Bcl10	BCL10 immune signaling adaptor. (239 aa)
	spint1	Serine peptidase inhibitor, Kunitz type 1 a. (506 aa)
	LOC103046093	Dishevelled segment polarity protein 1b. (726 aa)
	mthfd1l	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (978 aa)
	glmn	Glomulin, FKBP associated protein a. (590 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000041588	W5L3R0_ASTMX	ENSAMXP00000041588	ENSAMXP00000014472	Protein kinase domain-containing protein.	Dishevelled segment polarity protein 3b.	0.407
ENSAMXP00000041588	dvl2	ENSAMXP00000041588	ENSAMXP00000013503	Protein kinase domain-containing protein.	Dishevelled segment polarity protein 2.	0.402
LOC103023241	LOC103024963	ENSAMXP00000046396	ENSAMXP00000042699	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.900
LOC103023241	LOC103034112	ENSAMXP00000046396	ENSAMXP00000006381	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.905
LOC103023241	prkacb	ENSAMXP00000046396	ENSAMXP00000027261	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC103024223	LOC103035729	ENSAMXP00000011888	ENSAMXP00000013711	Secreted frizzled-related protein 2 like.	Dishevelled segment polarity protein 1a.	0.483
LOC103024223	LOC103042896	ENSAMXP00000011888	ENSAMXP00000034903	Secreted frizzled-related protein 2 like.	Dishevelled segment polarity protein 3a.	0.483
LOC103024223	LOC103046093	ENSAMXP00000011888	ENSAMXP00000051676	Secreted frizzled-related protein 2 like.	Dishevelled segment polarity protein 1b.	0.483
LOC103024223	W5L3R0_ASTMX	ENSAMXP00000011888	ENSAMXP00000014472	Secreted frizzled-related protein 2 like.	Dishevelled segment polarity protein 3b.	0.483
LOC103024223	dvl2	ENSAMXP00000011888	ENSAMXP00000013503	Secreted frizzled-related protein 2 like.	Dishevelled segment polarity protein 2.	0.483
LOC103024607	sdc4	ENSAMXP00000010023	ENSAMXP00000049860	Transforming growth factor beta; Belongs to the TGF-beta family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.643
LOC103024607	tgfb1	ENSAMXP00000010023	ENSAMXP00000002667	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
LOC103024963	LOC103023241	ENSAMXP00000042699	ENSAMXP00000046396	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.900
LOC103024963	LOC103034112	ENSAMXP00000042699	ENSAMXP00000006381	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.905
LOC103024963	prkacb	ENSAMXP00000042699	ENSAMXP00000027261	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.901
LOC103027200	setd2	ENSAMXP00000013499	ENSAMXP00000029975	Bromo domain-containing protein.	SET domain containing 2, histone lysine methyltransferase.	0.520
LOC103034112	LOC103023241	ENSAMXP00000006381	ENSAMXP00000046396	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.905
LOC103034112	LOC103024963	ENSAMXP00000006381	ENSAMXP00000042699	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.905
LOC103034112	prkacb	ENSAMXP00000006381	ENSAMXP00000027261	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC103035729	LOC103024223	ENSAMXP00000013711	ENSAMXP00000011888	Dishevelled segment polarity protein 1a.	Secreted frizzled-related protein 2 like.	0.483