47 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	f3	Coagulation factor IIIa. (290 aa)
	F3	Coagulation factor III, tissue factor. (293 aa)
	Htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (467 aa)
	LOC103031234	Prokineticin 2. (110 aa)
	LOC103021727	Vasoactive intestinal peptide. (153 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (802 aa)
	LOC103037777	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
	LOC103041996	ADAM metallopeptidase domain 17b. (841 aa)
	LOC103040838	Vascular endothelial growth factor Ba; Belongs to the PDGF/VEGF growth factor family. (243 aa)
	W5KGH6_ASTMX	Neurofibromin 1b. (2733 aa)
	LOC103025573	Vasoactive intestinal peptide b. (231 aa)
	W5KHG8_ASTMX	Regulatory associated protein of MTOR, complex 1. (1305 aa)
	W5KT32_ASTMX	Neurofibromin 1a. (2744 aa)
	W5KXA4_ASTMX	Secretogranin II (chromogranin C), b. (581 aa)
	Jcad	Junctional cadherin 5 associated a. (1554 aa)
	W5LD95_ASTMX	ADAM metallopeptidase domain 17a. (675 aa)
	ecm1	Extracellular matrix protein 1b. (490 aa)
	LOC103025241	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	LOC103027843	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	W5LSB9_ASTMX	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	LOC103027188	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	LOC103021920	JunE proto-oncogene, AP-1 transcription factor subunit. (353 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	ENSAMXP00000030711	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (179 aa)
	Vegfc	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (339 aa)
	ENSAMXP00000034094	Insulin-like growth factor 2a. (176 aa)
	LOC103032641	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
	LOC103042873	Midkine a. (145 aa)
	scg2	Uncharacterized protein. (676 aa)
	LOC103029324	Bone morphogenetic protein 16. (430 aa)
	LOC103038514	LRRCT domain-containing protein. (327 aa)
	aggf1	Angiogenic factor with G patch and FHA domains 1. (823 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
	ENSAMXP00000040109	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (144 aa)
	LOC103035447	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (265 aa)
	mydgf	Myeloid-derived growth factor. (169 aa)
	ENSAMXP00000040946	C-C motif chemokine. (133 aa)
	ENSAMXP00000042098	Midkine b. (157 aa)
	sirt6	Sirtuin 6. (396 aa)
	bmp4	TGF_BETA_2 domain-containing protein. (481 aa)
	ENSAMXP00000046398	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (270 aa)
	apela	Uncharacterized protein. (55 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	il10	Interleukin 10. (182 aa)
	sp1	Uncharacterized protein. (678 aa)
	ENSAMXP00000053597	Uncharacterized protein. (1310 aa)
	Prok1	Prokineticin 1. (107 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmpr2	LOC103029324	ENSAMXP00000030317	ENSAMXP00000037650	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 16.	0.970
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
Bmpr2	bmp4	ENSAMXP00000030317	ENSAMXP00000046234	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF_BETA_2 domain-containing protein.	0.970
ENSAMXP00000040109	Vegfc	ENSAMXP00000040109	ENSAMXP00000033799	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.585
ENSAMXP00000040946	il10	ENSAMXP00000040946	ENSAMXP00000049622	C-C motif chemokine.	Interleukin 10.	0.547
ENSAMXP00000046398	LOC103035447	ENSAMXP00000046398	ENSAMXP00000040217	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.517
ENSAMXP00000046398	Vegfc	ENSAMXP00000046398	ENSAMXP00000033799	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.408
LOC103021727	LOC103025573	ENSAMXP00000003641	ENSAMXP00000006866	Vasoactive intestinal peptide.	Vasoactive intestinal peptide b.	0.903
LOC103021920	Sirt1	ENSAMXP00000026691	ENSAMXP00000003809	JunE proto-oncogene, AP-1 transcription factor subunit.	Deacetylase sirtuin-type domain-containing protein.	0.776
LOC103021920	il10	ENSAMXP00000026691	ENSAMXP00000049622	JunE proto-oncogene, AP-1 transcription factor subunit.	Interleukin 10.	0.407
LOC103021920	sirt6	ENSAMXP00000026691	ENSAMXP00000042837	JunE proto-oncogene, AP-1 transcription factor subunit.	Sirtuin 6.	0.502
LOC103021920	sp1	ENSAMXP00000026691	ENSAMXP00000051043	JunE proto-oncogene, AP-1 transcription factor subunit.	Uncharacterized protein.	0.813
LOC103025241	LOC103027188	ENSAMXP00000025540	ENSAMXP00000026634	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.	0.603
LOC103025241	LOC103027843	ENSAMXP00000025540	ENSAMXP00000025711	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.	0.603
LOC103025241	W5LSB9_ASTMX	ENSAMXP00000025540	ENSAMXP00000025817	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family.	0.909
LOC103025241	apela	ENSAMXP00000025540	ENSAMXP00000049544	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.886
LOC103025573	LOC103021727	ENSAMXP00000006866	ENSAMXP00000003641	Vasoactive intestinal peptide b.	Vasoactive intestinal peptide.	0.903
LOC103027188	LOC103025241	ENSAMXP00000026634	ENSAMXP00000025540	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	0.603
LOC103027188	LOC103027843	ENSAMXP00000026634	ENSAMXP00000025711	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103027188	W5LSB9_ASTMX	ENSAMXP00000026634	ENSAMXP00000025817	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family.	0.603