12 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000029247	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
	MAFB	MAF bZIP transcription factor B. (420 aa)
	wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	W5LNH3_ASTMX	EGF-like domain-containing protein. (290 aa)
	W5K189_ASTMX	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1307 aa)
	W5KM20_ASTMX	Collagen and calcium binding EGF domains 1. (381 aa)
	PTPN14	Protein tyrosine phosphatase non-receptor type 14. (1229 aa)
	LOC103047839	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (460 aa)
	e2f8	E2F transcription factor 8. (898 aa)
	pkd2	Polycystic kidney disease 2. (903 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
ENSAMXP00000029247	wnt5a	ENSAMXP00000029247	ENSAMXP00000044616	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912
LOC103041475	Bmpr2	ENSAMXP00000049576	ENSAMXP00000030317	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
PTPN14	W5KM20_ASTMX	ENSAMXP00000010018	ENSAMXP00000008632	Protein tyrosine phosphatase non-receptor type 14.	Collagen and calcium binding EGF domains 1.	0.413
PTPN14	W5LNH3_ASTMX	ENSAMXP00000010018	ENSAMXP00000021385	Protein tyrosine phosphatase non-receptor type 14.	EGF-like domain-containing protein.	0.413
W5K189_ASTMX	W5KM20_ASTMX	ENSAMXP00000001349	ENSAMXP00000008632	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Collagen and calcium binding EGF domains 1.	0.564
W5KM20_ASTMX	PTPN14	ENSAMXP00000008632	ENSAMXP00000010018	Collagen and calcium binding EGF domains 1.	Protein tyrosine phosphatase non-receptor type 14.	0.413
W5KM20_ASTMX	W5K189_ASTMX	ENSAMXP00000008632	ENSAMXP00000001349	Collagen and calcium binding EGF domains 1.	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.564
W5LNH3_ASTMX	PTPN14	ENSAMXP00000021385	ENSAMXP00000010018	EGF-like domain-containing protein.	Protein tyrosine phosphatase non-receptor type 14.	0.413
wnt5a	ENSAMXP00000029247	ENSAMXP00000044616	ENSAMXP00000029247	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912