35 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5LKH9_ASTMX	CD226 molecule. (348 aa)
	hmces	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (358 aa)
	parp3	Poly [ADP-ribose] polymerase. (631 aa)
	ENSAMXP00000037285	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (689 aa)
	ENSAMXP00000035313	SET domain-containing protein. (2185 aa)
	W5LFE7_ASTMX	Tumor protein p53 binding protein, 1. (1622 aa)
	LOC103025343	SET domain-containing protein. (876 aa)
	W5LD04_ASTMX	Uncharacterized protein. (328 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (939 aa)
	LOC103035380	Uncharacterized protein. (444 aa)
	W5KSM1_ASTMX	ATPase family AAA domain containing 5a. (1807 aa)
	ENSAMXP00000052711	ATPase family AAA domain containing 5b. (772 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	clcf1	Cardiotrophin-like cytokine factor 1. (375 aa)
	ENSAMXP00000047619	CD40 molecule, TNF receptor superfamily member 5. (353 aa)
	LOC103037523	Uncharacterized protein. (377 aa)
	kmt5b	Lysine methyltransferase 5B. (829 aa)
	exosc3	Exosome component 3. (245 aa)
	ENSAMXP00000043107	TNF superfamily member 13; Belongs to the tumor necrosis factor family. (170 aa)
	ENSAMXP00000042552	Uncharacterized protein. (809 aa)
	LOC111190374	Uncharacterized protein. (256 aa)
	shld2	Si:ch211-134m17.9. (855 aa)
	W5LTF5_ASTMX	Zgc:101664. (247 aa)
	LOC107197146	Uncharacterized protein. (567 aa)
	ENSAMXP00000030600	Uncharacterized protein. (69 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (809 aa)
	LOC103044392	Uncharacterized protein. (300 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC103021873	Uncharacterized protein. (575 aa)
	LOC103041009	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	W5L5M7_ASTMX	THO complex 1. (613 aa)
	Nsd2	Nuclear receptor binding SET domain protein 2. (1468 aa)
	rif1	Replication timing regulatory factor 1. (2429 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	Tbx21	T-box transcription factor 21. (577 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000035313	W5LFE7_ASTMX	ENSAMXP00000035313	ENSAMXP00000018559	SET domain-containing protein.	Tumor protein p53 binding protein, 1.	0.422
ENSAMXP00000037285	msh2	ENSAMXP00000037285	ENSAMXP00000016339	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.995
ENSAMXP00000042552	LOC103041009	ENSAMXP00000042552	ENSAMXP00000005247	Uncharacterized protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.438
ENSAMXP00000047619	LOC103041009	ENSAMXP00000047619	ENSAMXP00000005247	CD40 molecule, TNF receptor superfamily member 5.	Tumor necrosis factor b (TNF superfamily, member 2).	0.696
ENSAMXP00000052711	msh2	ENSAMXP00000052711	ENSAMXP00000016339	ATPase family AAA domain containing 5b.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.433
LOC103024607	LOC103041009	ENSAMXP00000010023	ENSAMXP00000005247	Transforming growth factor beta; Belongs to the TGF-beta family.	Tumor necrosis factor b (TNF superfamily, member 2).	0.526
LOC103024607	tgfb1	ENSAMXP00000010023	ENSAMXP00000002667	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
LOC103025343	W5LFE7_ASTMX	ENSAMXP00000017767	ENSAMXP00000018559	SET domain-containing protein.	Tumor protein p53 binding protein, 1.	0.422
LOC103041009	ENSAMXP00000042552	ENSAMXP00000005247	ENSAMXP00000042552	Tumor necrosis factor b (TNF superfamily, member 2).	Uncharacterized protein.	0.438
LOC103041009	ENSAMXP00000047619	ENSAMXP00000005247	ENSAMXP00000047619	Tumor necrosis factor b (TNF superfamily, member 2).	CD40 molecule, TNF receptor superfamily member 5.	0.696
LOC103041009	LOC103024607	ENSAMXP00000005247	ENSAMXP00000010023	Tumor necrosis factor b (TNF superfamily, member 2).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.526
LOC103041009	LOC103044392	ENSAMXP00000005247	ENSAMXP00000033888	Tumor necrosis factor b (TNF superfamily, member 2).	Uncharacterized protein.	0.644
LOC103041009	LOC111190374	ENSAMXP00000005247	ENSAMXP00000040622	Tumor necrosis factor b (TNF superfamily, member 2).	Uncharacterized protein.	0.644
LOC103041009	PTPRC	ENSAMXP00000005247	ENSAMXP00000032906	Tumor necrosis factor b (TNF superfamily, member 2).	Protein tyrosine phosphatase receptor type C.	0.438
LOC103041009	Tbx21	ENSAMXP00000005247	ENSAMXP00000010803	Tumor necrosis factor b (TNF superfamily, member 2).	T-box transcription factor 21.	0.515
LOC103041009	tgfb1	ENSAMXP00000005247	ENSAMXP00000002667	Tumor necrosis factor b (TNF superfamily, member 2).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.526
LOC103041009	tgfb2	ENSAMXP00000005247	ENSAMXP00000052607	Tumor necrosis factor b (TNF superfamily, member 2).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.440
LOC103044392	LOC103041009	ENSAMXP00000033888	ENSAMXP00000005247	Uncharacterized protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.644
LOC111190374	LOC103041009	ENSAMXP00000040622	ENSAMXP00000005247	Uncharacterized protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.644
Nsd2	W5LFE7_ASTMX	ENSAMXP00000012840	ENSAMXP00000018559	Nuclear receptor binding SET domain protein 2.	Tumor protein p53 binding protein, 1.	0.726