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W5KF46_ASTMX W5KF46_ASTMX Npy2r Npy2r LOC103024223 LOC103024223 LOC103044660 LOC103044660 LOC103026238 LOC103026238 W5LD66_ASTMX W5LD66_ASTMX LOC103022359 LOC103022359 LOC103029394 LOC103029394 tgfbr2 tgfbr2 LOC103044922 LOC103044922 LOC103027015 LOC103027015 LOC103021920 LOC103021920 LOC103037035 LOC103037035 ENSAMXP00000028486 ENSAMXP00000028486 LOC103025318 LOC103025318 sfrp5 sfrp5 Bmpr2 Bmpr2 LOC107197257 LOC107197257 ENSAMXP00000033131 ENSAMXP00000033131 dhrs3 dhrs3 sema3c sema3c LOC103033399 LOC103033399 zfpm2 zfpm2 LOC103042559 LOC103042559 nkx2-6 nkx2-6 W5K9M8_ASTMX W5K9M8_ASTMX LOC103047622 LOC103047622 tbx3 tbx3 ENSAMXP00000047894 ENSAMXP00000047894 LOC103047056 LOC103047056 LOC103041475 LOC103041475 ENSAMXP00000049934 ENSAMXP00000049934 ilk ilk ENSAMXP00000053345 ENSAMXP00000053345
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
Npy2rNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
LOC103024223Secreted frizzled-related protein 2 like. (312 aa)
LOC103044660Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (492 aa)
LOC103026238Zinc finger protein, FOG family member 2b. (1118 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LOC103044922Dehydrogenase/reductase (SDR family) member 3a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (303 aa)
LOC103027015Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (393 aa)
LOC103021920JunE proto-oncogene, AP-1 transcription factor subunit. (353 aa)
LOC103037035Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (371 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
LOC103025318NK2 homeobox 5. (313 aa)
sfrp5Secreted frizzled-related protein 5. (313 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
LOC107197257Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
ENSAMXP00000033131G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3b. (321 aa)
sema3cSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (743 aa)
LOC103033399Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (419 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1151 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
nkx2-6Homeobox domain-containing protein. (294 aa)
W5K9M8_ASTMXUncharacterized protein. (174 aa)
LOC103047622Neuropilin; Belongs to the neuropilin family. (920 aa)
tbx3T-box transcription factor 3a. (706 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
LOC103047056Neuropeptide Y receptor Y2, like; Belongs to the G-protein coupled receptor 1 family. (376 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ENSAMXP00000049934Uncharacterized protein. (772 aa)
ilkIntegrin-linked kinase. (452 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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