STRINGSTRING
sall4 sall4 tgfb1 tgfb1 W5K5H8_ASTMX W5K5H8_ASTMX smad6 smad6 prdm1 prdm1 W5KFJ0_ASTMX W5KFJ0_ASTMX Npy2r Npy2r Hectd1 Hectd1 Tbx5 Tbx5 LOC103024607 LOC103024607 LOC103024223 LOC103024223 Nsd2 Nsd2 W5LD66_ASTMX W5LD66_ASTMX LOC103022359 LOC103022359 mstn mstn LOC103029394 LOC103029394 TMEM65 TMEM65 W5LL98_ASTMX W5LL98_ASTMX tgfbr2 tgfbr2 Trip11 Trip11 W5LRA5_ASTMX W5LRA5_ASTMX LOC103027015 LOC103027015 LOC103037035 LOC103037035 ENSAMXP00000028486 ENSAMXP00000028486 LOC103025318 LOC103025318 med1 med1 ccn1 ccn1 Bmpr2 Bmpr2 greb1 greb1 LOC107197257 LOC107197257 fgf8 fgf8 PTK7 PTK7 ENSAMXP00000033131 ENSAMXP00000033131 zmpste24 zmpste24 TNNC1 TNNC1 sema3c sema3c sav1 sav1 Cpe Cpe LOC103047410 LOC103047410 hace1 hace1 LOC103033399 LOC103033399 ENSAMXP00000040763 ENSAMXP00000040763 zfpm2 zfpm2 ENSAMXP00000041588 ENSAMXP00000041588 tmem65 tmem65 Cntrl Cntrl dctn5 dctn5 LOC103042559 LOC103042559 nprl3 nprl3 Tnni1 Tnni1 LOC103021519 LOC103021519 LOC103047056 LOC103047056 LOC107197240 LOC107197240 LOC103041475 LOC103041475 ptcd2 ptcd2 smad7 smad7 ENSAMXP00000053345 ENSAMXP00000053345 HAND1 HAND1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sall4Spalt-like transcription factor 4. (1107 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
W5K5H8_ASTMXPR domain containing 1b, with ZNF domain. (499 aa)
smad6Mothers against decapentaplegic homolog. (480 aa)
prdm1PR domain containing 1a, with ZNF domain. (755 aa)
W5KFJ0_ASTMXMothers against decapentaplegic homolog. (468 aa)
Npy2rNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
Hectd1HECT domain containing 1. (2595 aa)
Tbx5T-box transcription factor 5a. (522 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
LOC103024223Secreted frizzled-related protein 2 like. (312 aa)
Nsd2Nuclear receptor binding SET domain protein 2. (1468 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
mstnMyostatin b. (435 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
TMEM65Transmembrane protein 65. (233 aa)
W5LL98_ASTMXAryl-hydrocarbon receptor nuclear translocator 2. (630 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
Trip11Thyroid hormone receptor interactor 11. (1949 aa)
W5LRA5_ASTMXUncharacterized protein. (157 aa)
LOC103027015Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (393 aa)
LOC103037035Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (371 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
LOC103025318NK2 homeobox 5. (313 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1801 aa)
ccn1Cellular communication network factor 1. (372 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
greb1Growth regulating estrogen receptor binding 1. (1821 aa)
LOC107197257Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa)
ENSAMXP00000033131G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
TNNC1Uncharacterized protein. (161 aa)
sema3cSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (743 aa)
sav1Salvador family WW domain containing protein 1. (405 aa)
CpeCarboxypeptidase E. (454 aa)
LOC103047410Aryl hydrocarbon receptor nuclear translocator. (778 aa)
hace1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (932 aa)
LOC103033399Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (419 aa)
ENSAMXP00000040763Uncharacterized protein. (233 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1151 aa)
ENSAMXP00000041588Protein kinase domain-containing protein. (117 aa)
tmem65Transmembrane protein 65. (256 aa)
CntrlUncharacterized protein. (880 aa)
dctn5Dynactin 5. (182 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
nprl3NPR3-like, GATOR1 complex subunit. (655 aa)
Tnni1Troponin I type 1b (skeletal, slow). (170 aa)
LOC103021519Troponin C type 1b (slow). (214 aa)
LOC103047056Neuropeptide Y receptor Y2, like; Belongs to the G-protein coupled receptor 1 family. (376 aa)
LOC107197240BHLH domain-containing protein. (244 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ptcd2Pentatricopeptide repeat domain 2. (370 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
HAND1Heart and neural crest derivatives expressed 1. (157 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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