STRINGSTRING
cdk12 cdk12 ice1 ice1 LOC103040586 LOC103040586 ddx21 ddx21 ssu72 ssu72 setd2 setd2 plac8 plac8 gtf2b gtf2b gtf2a1 gtf2a1 Xbp1 Xbp1 med1 med1 eny2 eny2 SRF SRF LOC103025318 LOC103025318 ENSAMXP00000028486 ENSAMXP00000028486 gtf2e1 gtf2e1 LOC103026155 LOC103026155 LOC103029354 LOC103029354 LOC103029048 LOC103029048 W5LTQ8_ASTMX W5LTQ8_ASTMX zbtb1 zbtb1 taf13 taf13 LOC103029013 LOC103029013 LOC103042992 LOC103042992 W5LS26_ASTMX W5LS26_ASTMX nfil3 nfil3 polr2j polr2j snapc4 snapc4 wdr61 wdr61 polr2d polr2d ercc2 ercc2 supt5h supt5h LOC103025545 LOC103025545 LOC103022779 LOC103022779 Scaf1 Scaf1 ctr9 ctr9 W5KU27_ASTMX W5KU27_ASTMX taf11 taf11 ar ar W5KW74_ASTMX W5KW74_ASTMX Rpap1 Rpap1 LOC103043413 LOC103043413 LOC103023591 LOC103023591 bcl9 bcl9 W5KZQ7_ASTMX W5KZQ7_ASTMX polr2c polr2c POLR2F POLR2F W5L1C8_ASTMX W5L1C8_ASTMX ep300 ep300 W5L3I5_ASTMX W5L3I5_ASTMX SETX SETX ccnh ccnh LOC103036607 LOC103036607 W5LAU2_ASTMX W5LAU2_ASTMX adrm1 adrm1 LOC103031807 LOC103031807 W5LD23_ASTMX W5LD23_ASTMX W5LD66_ASTMX W5LD66_ASTMX ell ell gtf2h4 gtf2h4 snapc3 snapc3 LOC103025442 LOC103025442 prdm4 prdm4 etv1 etv1 ELOB ELOB polr2g polr2g gsx2 gsx2 nmi nmi ENSAMXP00000044352 ENSAMXP00000044352 LOC103030550 LOC103030550 ENSAMXP00000044772 ENSAMXP00000044772 Hltf Hltf ENSAMXP00000044959 ENSAMXP00000044959 LOC103030467 LOC103030467 fndc10 fndc10 ENSAMXP00000045626 ENSAMXP00000045626 atxn1l atxn1l taf7l taf7l Eloa Eloa LOC103044950 LOC103044950 ENSAMXP00000046363 ENSAMXP00000046363 gtf2h3 gtf2h3 elob elob taf10 taf10 taf2 taf2 ENSAMXP00000047894 ENSAMXP00000047894 ELOF1 ELOF1 elf3 elf3 ENSAMXP00000048556 ENSAMXP00000048556 ehf ehf pcid2 pcid2 LOC111193433 LOC111193433 ENSAMXP00000050157 ENSAMXP00000050157 supt6h supt6h Phrf1 Phrf1 Dr1 Dr1 ENSAMXP00000050895 ENSAMXP00000050895 drap1 drap1 LOC103032741 LOC103032741 ENSAMXP00000051962 ENSAMXP00000051962 gtf2h5 gtf2h5 gtf2h2c gtf2h2c ENSAMXP00000053049 ENSAMXP00000053049 LOC103030866 LOC103030866 ENSAMXP00000053345 ENSAMXP00000053345 nkx2-3 nkx2-3 snapc1 snapc1 LOC103046220 LOC103046220 ENSAMXP00000053637 ENSAMXP00000053637 med18 med18 polr2k polr2k ENSAMXP00000054367 ENSAMXP00000054367 nfatc2 nfatc2 tcea1 tcea1 LOC103022359 LOC103022359 gtf2h1 gtf2h1 POLR2E POLR2E W5LI45_ASTMX W5LI45_ASTMX cdk13 cdk13 LOC103029394 LOC103029394 LOC103031530 LOC103031530 rbmx rbmx Gtf2a1l Gtf2a1l nr1h4 nr1h4 paf1 paf1 W5LP72_ASTMX W5LP72_ASTMX Gtf2e2 Gtf2e2 supt16h supt16h W5JXX2_ASTMX W5JXX2_ASTMX W5JYC4_ASTMX W5JYC4_ASTMX ice2 ice2 W5K0L4_ASTMX W5K0L4_ASTMX W5K1S8_ASTMX W5K1S8_ASTMX Nfatc4 Nfatc4 polr2h polr2h Cdc73 Cdc73 W5K3P2_ASTMX W5K3P2_ASTMX Tcea2 Tcea2 TAF4 TAF4 POLR2B POLR2B pcf11 pcf11 Rb1 Rb1 taf3 taf3 taf6l taf6l gcm2 gcm2 W5KGB2_ASTMX W5KGB2_ASTMX ell2 ell2 W5KIT2_ASTMX W5KIT2_ASTMX W5KJ62_ASTMX W5KJ62_ASTMX ccdc124 ccdc124 polr2i polr2i ENSAMXP00000040725 ENSAMXP00000040725 ercc3 ercc3 ELOB-2 ELOB-2 gtf2ird1 gtf2ird1 LOC103044365 LOC103044365 ENSAMXP00000039272 ENSAMXP00000039272 polr2a polr2a ENSAMXP00000038736 ENSAMXP00000038736 LOC103044436 LOC103044436 MYOCD MYOCD ENSAMXP00000037899 ENSAMXP00000037899 ENSAMXP00000037494 ENSAMXP00000037494 taf12 taf12 ENSAMXP00000035178 ENSAMXP00000035178 taf8 taf8 ENSAMXP00000034843 ENSAMXP00000034843 MSX1 MSX1 supt3h supt3h LOC103037830 LOC103037830 ENSAMXP00000033395 ENSAMXP00000033395 polr2l polr2l ENSAMXP00000031926 ENSAMXP00000031926 ENSAMXP00000031886 ENSAMXP00000031886 ENSAMXP00000031013 ENSAMXP00000031013
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdk12Cyclin-dependent kinase 12. (1311 aa)
ice1KIAA0947-like (H. sapiens). (1623 aa)
LOC103040586Ets variant 5b. (531 aa)
ddx21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (784 aa)
ssu72SSU72 homolog, RNA polymerase II CTD phosphatase. (194 aa)
setd2SET domain containing 2, histone lysine methyltransferase. (2886 aa)
plac8Placenta associated 8, tandem duplicate 1. (111 aa)
gtf2bGeneral transcription factor IIB. (222 aa)
gtf2a1General transcription factor IIA, 1. (390 aa)
Xbp1X-box binding protein 1. (264 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1801 aa)
eny2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (118 aa)
SRFSerum response factor. (527 aa)
LOC103025318NK2 homeobox 5. (313 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
gtf2e1General transcription factor IIE, polypeptide 1, alpha. (440 aa)
LOC103026155Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (530 aa)
LOC103029354Nuclear factor, interleukin 3 regulated, member 6. (415 aa)
LOC103029048BZIP domain-containing protein. (570 aa)
W5LTQ8_ASTMXNuclear factor, interleukin 3 regulated, member 4. (256 aa)
zbtb1Zinc finger and BTB domain containing 1. (680 aa)
taf13TATA-box binding protein associated factor 13. (124 aa)
LOC103029013Nuclear factor, interleukin 3 regulated, member 5. (591 aa)
LOC103042992General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (265 aa)
W5LS26_ASTMXSi:dkey-29b11.3. (152 aa)
nfil3Nuclear factor, interleukin 3 regulated. (467 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
snapc4Small nuclear RNA activating complex, polypeptide 4. (1560 aa)
wdr61WD repeat domain 61. (305 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (143 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
supt5hTranscription elongation factor SPT5. (1082 aa)
LOC103025545Actin binding Rho activating protein a. (354 aa)
LOC103022779Ash1 (absent, small, or homeotic)-like (Drosophila). (2955 aa)
Scaf1SR-related CTD-associated factor 1. (1489 aa)
ctr9CTR9 homolog, Paf1/RNA polymerase II complex component. (1162 aa)
W5KU27_ASTMXTranscription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (541 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (202 aa)
arAndrogen receptor. (839 aa)
W5KW74_ASTMXSequestosome 1. (427 aa)
Rpap1RNA polymerase II associated protein 1. (1389 aa)
LOC103043413Nuclear receptor subfamily 1, group H, member 5. (495 aa)
LOC103023591Transmembrane protein 240a. (175 aa)
bcl9BCL9 transcription coactivator. (1594 aa)
W5KZQ7_ASTMXElongin A, like. (521 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
W5L1C8_ASTMXUncharacterized protein. (350 aa)
ep300E1A binding protein p300 b. (2652 aa)
W5L3I5_ASTMXATRX chromatin remodeler. (1989 aa)
SETXSenataxin. (2327 aa)
ccnhCyclin H; Belongs to the cyclin family. (321 aa)
LOC103036607Bromo domain-containing protein. (1917 aa)
W5LAU2_ASTMXTAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (804 aa)
adrm1Adhesion regulating molecule 1. (414 aa)
LOC103031807Uncharacterized protein. (427 aa)
W5LD23_ASTMXUncharacterized protein. (691 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
ellElongation factor RNA polymerase II. (636 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (467 aa)
snapc3Small nuclear RNA activating complex, polypeptide 3. (379 aa)
LOC103025442LIM homeobox 1a. (405 aa)
prdm4PR domain containing 4. (830 aa)
etv1Ets variant 1. (476 aa)
ELOBElongin B. (114 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
gsx2GS homeobox 2. (260 aa)
nmiUncharacterized protein. (376 aa)
ENSAMXP00000044352Uncharacterized protein. (197 aa)
LOC103030550Nuclear factor of activated T cells 5a. (1452 aa)
ENSAMXP00000044772CBFD_NFYB_HMF domain-containing protein. (184 aa)
HltfHelicase-like transcription factor. (958 aa)
ENSAMXP00000044959ATRX chromatin remodeler, like. (1613 aa)
LOC103030467General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (255 aa)
fndc10Uncharacterized protein. (413 aa)
ENSAMXP00000045626Uncharacterized protein. (97 aa)
atxn1lAtaxin 1-like. (870 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (427 aa)
EloaElongin A. (190 aa)
LOC103044950Protein S100; Belongs to the S-100 family. (101 aa)
ENSAMXP00000046363Uncharacterized protein. (211 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (307 aa)
elobUbiquitin-like domain-containing protein. (119 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (192 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1204 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
ELOF1Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
elf3E74-like factor 3 (ets domain transcription factor, epithelial-specific ). (367 aa)
ENSAMXP00000048556TATA box binding protein. (248 aa)
ehfEts homologous factor. (301 aa)
pcid2PCI domain containing 2. (399 aa)
LOC111193433Protein S100; Belongs to the S-100 family. (98 aa)
ENSAMXP00000050157Uncharacterized protein. (1647 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1743 aa)
Phrf1PHD and ring finger domains 1. (1568 aa)
Dr1Down-regulator of transcription 1. (179 aa)
ENSAMXP00000050895MNAT1 component of CDK activating kinase. (283 aa)
drap1DR1-associated protein 1 (negative cofactor 2 alpha). (228 aa)
LOC103032741Actin binding Rho activating protein b. (373 aa)
ENSAMXP00000051962LEO1 homolog, Paf1/RNA polymerase II complex component. (584 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
gtf2h2cGeneral transcription factor IIH subunit. (393 aa)
ENSAMXP00000053049TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (710 aa)
LOC103030866TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (249 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
nkx2-3NK2 homeobox 3. (328 aa)
snapc1Small nuclear RNA activating complex, polypeptide 1b. (363 aa)
LOC103046220Thioredoxin_11 domain-containing protein. (619 aa)
ENSAMXP00000053637ELL domain-containing protein. (64 aa)
med18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
polr2kUncharacterized protein. (109 aa)
ENSAMXP00000054367Transcription initiation factor TFIID subunit. (1854 aa)
nfatc2Nuclear factor of activated T cells 2a. (902 aa)
tcea1Transcription elongation factor A (SII), 1. (315 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (547 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
W5LI45_ASTMXTumor necrosis factor receptor superfamily, member 1a. (398 aa)
cdk13Cyclin-dependent kinase 13. (1426 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
LOC103031530TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor. (863 aa)
rbmxRNA binding motif protein X-linked. (384 aa)
Gtf2a1lUncharacterized protein. (62 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (486 aa)
paf1PAF1 homolog, Paf1/RNA polymerase II complex component. (521 aa)
W5LP72_ASTMXRTF1 homolog, Paf1/RNA polymerase II complex component. (685 aa)
Gtf2e2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (288 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1031 aa)
W5JXX2_ASTMXUncharacterized protein. (125 aa)
W5JYC4_ASTMXTATA box binding protein like 2. (313 aa)
ice2Interactor of little elongator complex ELL subunit 2. (973 aa)
W5K0L4_ASTMXMADS-box domain-containing protein. (479 aa)
W5K1S8_ASTMXSi:dkey-219c3.2. (1042 aa)
Nfatc4Nuclear factor of activated T cells 4. (812 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)
W5K3P2_ASTMXHomeobox domain-containing protein. (152 aa)
Tcea2Transcription elongation factor A (SII), 2. (318 aa)
TAF4TATA-box binding protein associated factor 4. (839 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1053 aa)
pcf11PCF11 cleavage and polyadenylation factor subunit. (1499 aa)
Rb1Retinoblastoma 1. (882 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (909 aa)
taf6lTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (642 aa)
gcm2Glial cells missing transcription factor 2. (493 aa)
W5KGB2_ASTMXNuclear factor of activated T cells 5b. (1450 aa)
ell2Elongation factor, RNA polymerase II, 2. (648 aa)
W5KIT2_ASTMXActin binding LIM protein family, member 3. (550 aa)
W5KJ62_ASTMXSi:ch211-13k12.2. (555 aa)
ccdc124Coiled-coil domain containing 124. (215 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
ENSAMXP00000040725Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (99 aa)
ercc3Excision repair cross-complementation group 3. (781 aa)
ELOB-2Elongin B. (114 aa)
gtf2ird1GTF2I repeat domain containing 1. (976 aa)
LOC103044365E1A binding protein p300 a. (2671 aa)
ENSAMXP00000039272Uncharacterized protein. (274 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
ENSAMXP00000038736Ets variant 7. (242 aa)
LOC103044436Transcription elongation factor A (SII), 3. (656 aa)
MYOCDMyocardin. (999 aa)
ENSAMXP00000037899MADS-box domain-containing protein. (356 aa)
ENSAMXP00000037494Uncharacterized protein. (448 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (162 aa)
ENSAMXP00000035178Uncharacterized protein. (379 aa)
taf8TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (297 aa)
ENSAMXP00000034843Uncharacterized protein. (55 aa)
MSX1Msh homeobox 1. (201 aa)
supt3hSPT3 homolog, SAGA and STAGA complex component. (387 aa)
LOC103037830GATA binding protein 2a. (469 aa)
ENSAMXP00000033395GATA binding protein 1a. (372 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
ENSAMXP00000031926TAFH domain-containing protein. (965 aa)
ENSAMXP00000031886Small nuclear RNA activating complex, polypeptide 5. (119 aa)
ENSAMXP00000031013AAA domain-containing protein. (491 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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